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Biology and Biochemistry

D-Index
63
Citations
22608
World Ranking
9996
National Ranking
4377

Overview

Patrick M.A. Sleiman is affiliated with the Children's Hospital of Philadelphia in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broad areas, their focus includes key subfields such as Genetics, Molecular Biology, Surgery, Physiology, and Immunology.

Their scientific contributions cover multiple topics, including Genetic Associations and Epidemiology, Asthma and Respiratory Diseases, Genomics and Rare Diseases, Pancreatic Function and Diabetes, IL-33, ST2, and ILC Pathways, Genomic Variations and Chromosomal Abnormalities, and Diabetes and Associated Disorders.

Patrick M.A. Sleiman has published extensively, with a notable presence in several scientific venues. The most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Genetics in Medicine Open
  • Nature Communications
  • Scientific Reports
  • Journal of Allergy and Clinical Immunology

Representative recent papers include:

  • Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups, 2020, The American Journal of Human Genetics
  • European and Multi-Ancestry Genome-Wide Association Meta-Analysis of Atopic Dermatitis Highlights Importance of Systemic Immune Regulation, 2023, Nature Communications
  • A Genome-Wide Association Study of Polycystic Ovary Syndrome Identified from Electronic Health Records, 2020, American Journal of Obstetrics and Gynecology
  • Rare Copy Number Variants in Over 100,000 European Ancestry Subjects Reveal Multiple Disease Associations, 2020, Nature Communications
  • Common Genetic Variants on 5p14.1 Associate with Autism Spectrum Disorders, 2020, UNC Libraries

Collaboration has been a significant aspect of Sleiman's research activity, with frequent co-authors including:

  • Hákon Hákonarson
  • Joseph Glessner
  • Hui-Qi Qu
  • Xiao Chang
  • Frank Mentch

Best Publications

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

    Joseph T. Glessner;Kai Wang;Guiqing Cai;Olena Korvatska

  • Common genetic variants on 5p14.1 associate with autism spectrum disorders

    Kai Wang;Haitao Zhang;Deqiong Ma;Maja Bucan

  • Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

    Günter U. Höglinger;Nadine M. Melhem;Dennis W. Dickson;Patrick M A Sleiman

  • Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

    Lavinia Paternoster;Marie Standl;Johannes Waage;Hansjoerg Baurecht

  • A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

    Klaus Bønnelykke;Patrick Sleiman;Kasper Nielsen;Eskil Kreiner-Møller

  • Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

    Vivianna M. Van Deerlin;Patrick M A Sleiman;Maria Martinez-Lage;Maria Martinez-Lage;Alice Chen-Plotkin

  • Neuroimaging of the Philadelphia neurodevelopmental cohort.

    Theodore D. Satterthwaite;Mark A. Elliott;Kosha Ruparel;James Loughead

  • Common variants at five new loci associated with early-onset inflammatory bowel disease.

    Marcin Imielinski;Robert N. Baldassano;Anne Griffiths;Richard K. Russell

  • Common variants at 5q22 associate with pediatric eosinophilic esophagitis.

    Marc E. Rothenberg;Jonathan M. Spergel;Jonathan M. Spergel;Joseph D. Sherrill;Kiran Annaiah

  • Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder

    Josephine Elia;Joseph T. Glessner;Kai Wang;Nagahide Takahashi

  • Thymic stromal lymphopoietin–elicited basophil responses promote eosinophilic esophagitis

    Mario Noti;Elia D.Tait Wojno;Brian S. Kim;Mark C. Siracusa

  • Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

    Subra Kugathasan;Robert N Baldassano;Jonathan P Bradfield;Patrick M A Sleiman

  • Variants of DENND1B Associated with Asthma in Children

    Patrick M. A. Sleiman;James Flory;Marcin Imielinski;Jonathan P. Bradfield

  • Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.

    Lavinia Paternoster;Marie Standl;Chih-Mei Chen;Adaikalavan Ramasamy

  • The Philadelphia Neurodevelopmental Cohort: A publicly available resource for the study of normal and abnormal brain development in youth.

    Theodore D. Satterthwaite;John J. Connolly;Kosha Ruparel;Monica E. Calkins

  • A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.

    Jonathan P. Bradfield;Hui Qi Qu;Kai Wang;Haitao Zhang

  • Genome-wide Association Analysis Identifies PDE4D as an Asthma-Susceptibility Gene

    Blanca E. Himes;Gary M. Hunninghake;James W. Baurley;Nicholas M. Rafaels

  • Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases

    Rong Chen;Lisong Shi;Jörg Hakenberg;Brian Naughton

  • A genome-wide association meta-analysis identifies new childhood obesity loci

    Bradfield Jp;Taal Hr;Timpson Nj;Scherag A

Frequent Co-Authors

Hakon Hakonarson
Hakon Hakonarson Children's Hospital of Philadelphia
Joseph T. Glessner
Joseph T. Glessner Children's Hospital of Philadelphia
Struan F.A. Grant
Struan F.A. Grant University of Pennsylvania
Jonathan P. Bradfield
Jonathan P. Bradfield Children's Hospital of Philadelphia
Rosetta M. Chiavacci
Rosetta M. Chiavacci Children's Hospital of Philadelphia
Jonathan M. Spergel
Jonathan M. Spergel University of Pennsylvania
Gail P. Jarvik
Gail P. Jarvik University of Washington
Hans Bisgaard
Hans Bisgaard University of Copenhagen
Erik Melén
Erik Melén Karolinska Institute
Brendan J. Keating
Brendan J. Keating University of Pennsylvania

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