World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
69
Citations
18217
World Ranking
2343
National Ranking
1058

Overview

Brendan J. Keating is affiliated with the University of Pennsylvania in the United States and works primarily in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their research spans several subfields, including Surgery, Genetics, Transplantation, Molecular Biology, and Cardiology and Cardiovascular Medicine.

The scientist's research focuses on topics such as Renal Transplantation Outcomes and Treatments, Xenotransplantation and immune response, Genetic Associations and Epidemiology, Organ Transplantation Techniques and Outcomes, Transplantation Methods and Outcomes, Tissue Engineering and Regenerative Medicine, and Animal Genetics and Reproduction.

Among their recent papers are the following:

  • Results of Two Cases of Pig-to-Human Kidney Xenotransplantation (2022, New England Journal of Medicine)
  • Pig-to-human heart xenotransplantation in two recently deceased human recipients (2023, Nature Medicine)
  • Immune response after pig-to-human kidney xenotransplantation: a multimodal phenotyping study (2023, The Lancet)
  • Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23 (2021, European Heart Journal)
  • Rare copy number variants in over 100,000 European ancestry subjects reveal multiple disease associations (2020, Nature Communications)

Frequent coauthors collaborating with Brendan J. Keating include:

  • Adam Griesemer
  • Jeffrey Stern
  • Vasishta Tatapudi
  • David Ayares
  • Robert A. Montgomery

Common publication venues for their work are:

  • UNC Libraries
  • American Journal of Transplantation
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Transplantation
  • Nature Medicine

Best Publications

  • The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.

    D I Swerdlow;M V Holmes;K B Kuchenbaecker

  • Association between alcohol and cardiovascular disease:Mendelian randomisation analysis based on individual participant data

    Michael V Holmes;Michael V Holmes;Caroline E Dale;Luisa Zuccolo;Richard J Silverwood

  • HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.

    Daniel I Swerdlow;David Preiss;Karoline B Kuchenbaecker;Michael Holmes

  • Mendelian randomization of blood lipids for coronary heart disease

    Michael V. Holmes;Folkert W. Asselbergs;Tom M. Palmer;Fotios Drenos

  • Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies

    Brendan J. Keating;Sam Tischfield;Sam Tischfield;Sarah S. Murray;Tushar Bhangale

  • The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

    Georg B. Ehret;Georg B. Ehret;Teresa Ferreira;Daniel I. Chasman;Anne U. Jackson

  • Return of Genomic Results to Research Participants: The Floor, the Ceiling, and the Choices In Between

    Gail P. Jarvik;Laura M. Amendola;Jonathan S. Berg

  • Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project

    Guillaume Lettre;Cameron D. Palmer;Cameron D. Palmer;Taylor Young;Kenechi G. Ejebe

  • PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

    Amand F Schmidt;Daniel I Swerdlow;Daniel I Swerdlow;Michael V Holmes;Michael V Holmes;Riyaz S Patel;Riyaz S Patel

  • The landscape of recombination in African Americans

    Anjali G. Hinch;Arti Tandon;Arti Tandon;Nick Patterson;Yunli Song

  • The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration

    Silvia Paracchini;Ankur Thomas;Sandra Castro;Cecilia Lai

  • Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci

    Folkert W. Asselbergs;Yiran Guo;Yiran Guo;Erik P A Van Iperen;Suthesh Sivapalaratnam

  • Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease

    Adam S. Butterworth;Peter S. Braund;Martin Farrall;Robert J. Hardwick

  • A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

    Keri L. Monda;Keri L. Monda;Gary K. Chen;Kira C. Taylor;Kira C. Taylor;Cameron Palmer;Cameron Palmer

  • Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci

    Richa Saxena;Richa Saxena;Clara C. Elbers;Clara C. Elbers;Yiran Guo;Inga Peter

  • In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading.

    Julian C. Knight;Julian C. Knight;Brendan J. Keating;Kirk A. Rockett;Dominic P. Kwiatkowski;Dominic P. Kwiatkowski

  • Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

    Yun R Li;Jin Li;Sihai D Zhao;Sihai D Zhao;Jonathan P Bradfield

  • Association of Lipid Fractions With Risks for Coronary Artery Disease and Diabetes

    Jon White;Daniel I. Swerdlow;David Preiss;Zammy Fairhurst-Hunter

  • Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis.

    Michael V. Holmes;Michael V. Holmes;Leslie A. Lange;Tom M. Palmer;Matthew B. Lanktree

  • Trans-ethnic genome-wide association studies: advantages and challenges of mapping in diverse populations

    Yun R Li;Brendan J Keating

Frequent Co-Authors

Hakon Hakonarson
Hakon Hakonarson Children's Hospital of Philadelphia
Yun Li
Yun Li University of North Carolina at Chapel Hill
Alexander P. Reiner
Alexander P. Reiner University of Washington
Leslie A. Lange
Leslie A. Lange University of Colorado Anschutz Medical Campus
Paul I. W. de Bakker
Paul I. W. de Bakker Vertex Pharmaceuticals (United Kingdom)
Susan Redline
Susan Redline Brigham and Women's Hospital
Aroon D. Hingorani
Aroon D. Hingorani University College London
James G. Wilson
James G. Wilson University of Mississippi Medical Center
Bruce M. Psaty
Bruce M. Psaty University of Washington

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