World's Best Scientists 2026 revealed!

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Genetics

D-Index
78
Citations
28583
World Ranking
1680
National Ranking
772

Overview

Jonathan P. Bradfield is affiliated with the Children's Hospital of Philadelphia in the United States. Their research spans multiple areas in biochemistry, genetics, molecular biology, and medicine, with a focus on subfields such as genetics, molecular biology, pediatrics, perinatology and child health, surgery, and epidemiology.

The scientist's recent publications demonstrate involvement in significant studies related to genetic and epidemiological research. Notable papers include "A saturated map of common genetic variants associated with human height" (2022, Nature), "GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture" (2023, Nature Genetics), "Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes" (2020, Diabetes), "Rare copy number variants in over 100,000 European ancestry subjects reveal multiple disease associations" (2020, Nature Communications), and "Genetic effects on the timing of parturition and links to fetal birth weight" (2023, Nature Genetics).

Frequent co-authors collaborating with Bradfield include:

  • Hákon Hákonarson (35 publications)
  • Struan F.A. Grant (23 publications)
  • Alessandra Chesi (13 publications)
  • Joseph Glessner (13 publications)
  • Matthew Allison (10 publications)

The most common publication venues for Bradfield's work are:

  • UNC Libraries (16 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (8 publications)
  • Nature Communications (4 publications)
  • Nature Genetics (3 publications)
  • Human Genetics and Genomics Advances (3 publications)

Bradfield's research covers several main topics including:

  • Genetic Associations and Epidemiology
  • Birth, Development, and Health
  • Diabetes and associated disorders
  • Pancreatic function and diabetes
  • Genetic and phenotypic traits in livestock
  • Genetics and Neurodevelopmental Disorders
  • Genomic variations and chromosomal abnormalities

With extensive published work in genetics and molecular biology, Bradfield's contributions provide data relevant to understanding developmental biology, disease risk factors, and genetic variation across populations.

Best Publications

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

    Joseph T. Glessner;Kai Wang;Guiqing Cai;Olena Korvatska

  • Common genetic variants on 5p14.1 associate with autism spectrum disorders

    Kai Wang;Haitao Zhang;Deqiong Ma;Maja Bucan

  • A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene

    Hakon Hakonarson;Struan F A Grant;Jonathan P. Bradfield;Luc Marchand

  • Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

    Nicole M Warrington;Robin N Beaumont;Momoko Horikoshi;Felix R Day

  • Common variants at five new loci associated with early-onset inflammatory bowel disease.

    Marcin Imielinski;Robert N. Baldassano;Anne Griffiths;Richard K. Russell

  • Genome-wide associations for birth weight and correlations with adult disease

    Momoko Horikoshi;Robin N. Beaumont;Felix R. Day;Nicole M. Warrington;Nicole M. Warrington

  • A genome-wide association meta-analysis identifies new childhood obesity loci

    JP Bradfield;HR Taal;NJ Timpson;A Scherag

  • Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes

    Maja Bucan;Brett S. Abrahams;Kai Wang;Joseph T. Glessner

  • Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

    Bassel Abou-Khalil;Pauls Auce;Andreja Avbersek;Melanie Bahlo

  • Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder

    Josephine Elia;Joseph T. Glessner;Kai Wang;Nagahide Takahashi

  • Copy number variation at 1q21.1 associated with neuroblastoma

    Sharon J. Diskin;Cuiping Hou;Joseph T. Glessner;Edward F. Attiyeh;Edward F. Attiyeh

  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Valérie Turcot;Yingchang Lu;Yingchang Lu;Heather M Highland;Heather M Highland;Claudia Schurmann

  • High-resolution mapping and analysis of copy number variations in the human genome: A data resource for clinical and research applications

    Tamim H. Shaikh;Xiaowu Gai;Juan C. Perin;Joseph T. Glessner

  • Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

    Subra Kugathasan;Robert N Baldassano;Jonathan P Bradfield;Patrick M A Sleiman

  • Variants of DENND1B Associated with Asthma in Children

    Patrick M. A. Sleiman;James Flory;Marcin Imielinski;Jonathan P. Bradfield

  • A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.

    Jonathan P. Bradfield;Hui Qi Qu;Kai Wang;Haitao Zhang

  • Common variations in BARD1 influence susceptibility to high-risk neuroblastoma

    Mario Capasso;Marcella Devoto;Cuiping Hou;Shahab Asgharzadeh

  • A genome-wide association meta-analysis identifies new childhood obesity loci

    Bradfield Jp;Taal Hr;Timpson Nj;Scherag A

Frequent Co-Authors

Hakon Hakonarson
Hakon Hakonarson Children's Hospital of Philadelphia
Struan F.A. Grant
Struan F.A. Grant University of Pennsylvania
Joseph T. Glessner
Joseph T. Glessner Children's Hospital of Philadelphia
Patrick M.A. Sleiman
Patrick M.A. Sleiman Children's Hospital of Philadelphia
Mads Melbye
Mads Melbye University of Copenhagen
Rosetta M. Chiavacci
Rosetta M. Chiavacci Children's Hospital of Philadelphia
Hans Bisgaard
Hans Bisgaard University of Copenhagen
Elina Hyppönen
Elina Hyppönen University of South Australia
Craig E. Pennell
Craig E. Pennell University of Newcastle Australia

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Exploring these pathways can complement a background in genetics and open doors to diverse and rewarding careers in healthcare and life sciences.

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