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Dominic Grün

Dominic Grün

D-Index & Metrics

Biology and Biochemistry

D-Index
45
Citations
21964
World Ranking
19022
National Ranking
1303

Overview

Dominic Grün is affiliated with the Max Planck Society in Germany. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, as well as medicine and immunology and microbiology. Their work spans various subfields, notably molecular biology, immunology, hematology, cancer research, and hepatology.

The scientist's research interests involve multiple interdisciplinary topics, including:

  • Single-cell and spatial transcriptomics
  • Immune cell function and interaction
  • T-cell and B-cell immunology
  • Epigenetics and DNA methylation
  • Gene regulatory network analysis
  • Cancer genomics and diagnostics
  • Hematopoietic stem cell transplantation

Dominic Grün has contributed to numerous recent publications, reflecting their active engagement in cutting-edge research. Some selected papers include:

  • "Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease," 2020, Nature Communications
  • "Benchmarking single-cell RNA-sequencing protocols for cell atlas projects," 2020, Nature Biotechnology
  • "Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids," 2021, Cell Stem Cell
  • "The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming," 2022, Cell Metabolism
  • "LifeTime and improving European healthcare through cell-based interceptive medicine," 2020, Nature

The researcher frequently publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • Nature Cell Biology
  • Nature
  • Immunity

Collaboration is a significant aspect of Dominic Grün's work. Frequent co-authors include:

  • Sagar Sagar
  • Josip S. Herman
  • Nina Cabezas-Wallscheid
  • Patrice Zeis
  • Nadim Aizarani

Best Publications

  • Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution.

    Takahiro Masuda;Roman Sankowski;Ori Staszewski;Chotima Böttcher

  • Single-cell messenger RNA sequencing reveals rare intestinal cell types

    Dominic Grün;Dominic Grün;Anna Lyubimova;Anna Lyubimova;Lennart Kester;Lennart Kester;Kay Wiebrands;Kay Wiebrands

  • A Single-Cell Transcriptome Atlas of the Human Pancreas

    Mauro J. Muraro;Gitanjali Dharmadhikari;Dominic Grün;Dominic Grün;Nathalie Groen

  • A human liver cell atlas reveals heterogeneity and epithelial progenitors.

    Nadim Aizarani;Nadim Aizarani;Antonio Saviano;Antonio Saviano;Sagar;Laurent Mailly;Laurent Mailly

  • Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation

    Marta Joana Costa Jordão;Roman Sankowski;Stefanie M. Brendecke;Sagar

  • Validation of noise models for single-cell transcriptomics

    Dominic Grün;Dominic Grün;Lennart Kester;Lennart Kester;Alexander van Oudenaarden;Alexander van Oudenaarden

  • Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

    Marta Olah;Vilas Menon;Naomi Habib;Naomi Habib;Mariko F. Taga

  • A Genome-Wide Map of Conserved MicroRNA Targets in C. elegans

    Sabbi Lall;Dominic Grün;Azra Krek;Kevin Chen;Kevin Chen

  • microRNA Target Predictions across Seven Drosophila Species and Comparison to Mammalian Targets

    Dominic Grün;Yi Lu Wang;David Langenberger;Kristin C. Gunsalus

  • De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data

    Dominic Grün;Dominic Grün;Dominic Grün;Mauro J. Muraro;Mauro J. Muraro;Jean Charles Boisset;Jean Charles Boisset;Kay Wiebrands;Kay Wiebrands

  • A new fate mapping system reveals context-dependent random or clonal expansion of microglia

    Tuan Leng Tay;Dominic Mai;Jana Dautzenberg;Francisco Fernández-Klett

  • Design and Analysis of Single-Cell Sequencing Experiments

    Dominic Grün;Dominic Grün;Dominic Grün;Alexander van Oudenaarden;Alexander van Oudenaarden

  • Single cell RNA sequencing of human microglia uncovers a subset that is associated with Alzheimer’s disease: Molecular and cell biology: Inflammatory and microglia‐mediated mechanisms in AD

    Marta Olah;Vilas Menon;Naomi Habib;Mariko Taga

  • Benchmarking Single-Cell RNA Sequencing Protocols for Cell Atlas Projects

    Elisabetta Mereu;Atefeh Lafzi;Catia Moutinho;Christoph Ziegenhain

  • Mapping microglia states in the human brain through the integration of high-dimensional techniques

    Roman Sankowski;Chotima Böttcher;Takahiro Masuda;Laufey Geirsdottir

  • FateID infers cell fate bias in multipotent progenitors from single-cell RNA-seq data.

    Josip S Herman;Josip S Herman;Sagar;Dominic Grün

  • Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart

    Hessel Honkoop;Dennis Em de Bakker;Alla Aharonov;Fabian Kruse

  • Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration

    Chi Chung Wu;Fabian Kruse;Mohankrishna Dalvoy Vasudevarao;Jan Philipp Junker

  • A Subset of Skin Macrophages Contributes to the Surveillance and Regeneration of Local Nerves

    Julia Kolter;Reinhild Feuerstein;Patrice Zeis;Patrice Zeis;Nora Hagemeyer

  • In vivo and transcriptome-wide identification of RNA binding protein target sites.

    Anna-Carina Jungkamp;Marlon Stoeckius;Desirea Mecenas;Dominic Grün

Frequent Co-Authors

Alexander van Oudenaarden
Alexander van Oudenaarden University Medical Center Utrecht
Asifa Akhtar
Asifa Akhtar Max Planck Society
Marco Prinz
Marco Prinz University of Freiburg
Nikolaus Rajewsky
Nikolaus Rajewsky Max Delbrück Center for Molecular Medicine
Josef Priller
Josef Priller Charité - University Medicine Berlin
Aviv Regev
Aviv Regev Genentech
Rolf Backofen
Rolf Backofen University of Freiburg
Rudolf Grosschedl
Rudolf Grosschedl Max Planck Society
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Oliver Stegle
Oliver Stegle German Cancer Research Center

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