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Genetics
Germany
2024

D-Index & Metrics

Genetics

D-Index
93
Citations
81312
World Ranking
946
National Ranking
80

Molecular Biology

D-Index
93
Citations
81312
World Ranking
661
National Ranking
56

Research.com Recognitions

  • 2024 - Research.com Genetics in Germany Leader Award
  • 2023 - Research.com Genetics in Germany Leader Award
  • 2019 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Biochemistry and Biophysics
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Nikolaus Rajewsky is affiliated with the Max Delbrück Center for Molecular Medicine in Germany. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a specialization in molecular biology. The areas of study extend to cancer research, immunology, biophysics, and infectious diseases.

The scientist's work covers a broad range of topics including single-cell and spatial transcriptomics, RNA research and splicing, circular RNAs in diseases, microRNA in disease regulation, RNA modifications and cancer, cell image analysis techniques, and mitochondrial function and pathology.

Rajewsky has contributed to numerous scientific publications, appearing frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), Zenodo (CERN European Organization for Nuclear Research), Nature Communications, Cell Reports, and the Journal of Visualized Experiments.

Recent papers include:

  • Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy, 2021, iScience
  • Single-cell and spatial transcriptomics: deciphering brain complexity in health and disease, 2023, Nature Reviews Neurology
  • Best practice standards for circular RNA research, 2022, Nature Methods
  • LifeTime and improving European healthcare through cell-based interceptive medicine, 2020, Nature
  • Open-ST: High-resolution spatial transcriptomics in 3D, 2024, Cell

Frequent collaborators include Nikos Karaiskos, Ivano Legnini, Anastasiya Boltengagen, Agnieszka Rybak-Wolf, and Tancredi Massimo Pentimalli. These collaborations highlight Rajewsky's engagement with a diverse network of researchers in related fields.

Among notable recognitions, Rajewsky was awarded membership in the German National Academy of Sciences Leopoldina in 2019, represented by the sections of Biochemistry and Biophysics. Additionally, they are a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Circular RNAs are a large class of animal RNAs with regulatory potency

    Sebastian Memczak;Marvin Jens;Antigoni Elefsinioti;Francesca Torti

  • Combinatorial microRNA target predictions.

    Azra Krek;Dominic Grün;Matthew N Poy;Rachel Wolf

  • Silencing of microRNAs in vivo with ‘antagomirs’

    Jan Krützfeldt;Nikolaus Rajewsky;Ravi Braich;Kallanthottathil G. Rajeev

  • Widespread changes in protein synthesis induced by microRNAs

    Matthias Selbach;Björn Schwanhäusser;Nadine Thierfelder;Zhuo Fang

  • circRNA Biogenesis Competes with Pre-mRNA Splicing

    Reut Ashwal-Fluss;Markus Meyer;Nagarjuna Reddy Pamudurti;Andranik Ivanov

  • miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades.

    Marc R. Friedländer;Sebastian D. Mackowiak;Na Li;Wei Chen

  • A pancreatic islet-specific microRNA regulates insulin secretion

    Matthew N. Poy;Lena Eliasson;Jan Krutzfeldt;Satoru Kuwajima

  • Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

    Agnieszka Rybak-Wolf;Christin Stottmeister;Petar Glažar;Marvin Jens

  • Regulation of the Germinal Center Response by MicroRNA-155

    To-Ha Thai;Dinis Pedro Calado;Stefano Casola;K. Mark Ansel

  • The evolution of gene regulation by transcription factors and microRNAs

    Kevin Chen;Nikolaus Rajewsky

  • Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

    Ivano Legnini;Gaia Di Timoteo;Francesca Rossi;Mariangela Morlando

  • circBase: a database for circular RNAs

    Petar Glažar;Panagiotis Papavasileiou;Nikolaus Rajewsky

  • Translation of CircRNAs

    Nagarjuna Reddy Pamudurti;Osnat Bartok;Marvin Jens;Reut Ashwal-Fluss

  • Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.

    Jonas Schulte-Schrepping;Nico Reusch;Daniela Paclik;Kevin Baßler

  • microRNA target predictions in animals.

    Nikolaus Rajewsky

  • Discovering microRNAs from deep sequencing data using miRDeep

    Marc R Friedländer;Wei Chen;Catherine Adamidi;Jonas Maaskola

  • MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb

    Changchun Xiao;Dinis Pedro Calado;Gunther Galler;To-Ha Thai

  • PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells

    F. Alexander Wolf;Fiona K. Hamey;Mireya Plass;Jordi Solana

  • Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project

    Mark B. Gerstein;Zhi John Lu;Eric L. Van Nostrand;Chao Cheng

  • Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

    Monika Piwecka;Petar Glažar;Luis R. Hernandez-Miranda;Sebastian Memczak

Frequent Co-Authors

Markus Landthaler
Markus Landthaler Max Delbrück Center for Molecular Medicine
Fabio Piano
Fabio Piano New York University
Julie Ahringer
Julie Ahringer University of Cambridge
Susan Strome
Susan Strome University of California, Santa Cruz
Michael J. MacCoss
Michael J. MacCoss University of Washington
Eran Segal
Eran Segal Weizmann Institute of Science
Lincoln Stein
Lincoln Stein Ontario Institute for Cancer Research
Steven Henikoff
Steven Henikoff Fred Hutchinson Cancer Research Center
Michael Snyder
Michael Snyder Stanford University
Chao Cheng
Chao Cheng Baylor College of Medicine

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