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D-Index & Metrics

Genetics

D-Index
70
Citations
20289
World Ranking
2260
National Ranking
166

Research.com Recognitions

  • 2005 - Fellow of Alfred P. Sloan Foundation

Overview

Uwe Ohler is affiliated with the Max Delbrück Center for Molecular Medicine in Germany. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a strong concentration in molecular biology among 139 publications. The subfields of interest also include immunology, plant science, cancer research, and biophysics.

The scientific topics that feature prominently in Ohler's work cover single-cell and spatial transcriptomics, RNA and protein synthesis mechanisms, RNA research and splicing, and RNA modifications related to cancer. Other areas include genomics and chromatin dynamics, genomics and phylogenetic studies, and cell image analysis techniques.

Ohler has contributed frequently to several major scientific publication venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature Structural & Molecular Biology
  • Cell Genomics
  • Developmental Cell

Recent papers reflect a range of topics and journals, such as:

  • A single-cell Arabidopsis root atlas reveals developmental trajectories in wild-type and cell identity mutants (2022, Developmental Cell)
  • Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes (2020, Nature Communications)
  • Standardized annotation of translated open reading frames (2022, Nature Biotechnology)
  • Brassinosteroid gene regulatory networks at cellular resolution in the Arabidopsis root (2023, Science)
  • Deep neural networks for interpreting RNA-binding protein target preferences (2020, Genome Research)

Ohler collaborates frequently with other researchers including Che-Wei Hsu, Markus Landthaler, Philip N. Benfey, Pia Rautenstrauch, and Remo Monti.

Additionally, Ohler was awarded the fellowship of the Alfred P. Sloan Foundation in 2005.

Best Publications

  • Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.

    Jonas Schulte-Schrepping;Nico Reusch;Daniela Paclik;Kevin Baßler

  • A High-Resolution Root Spatiotemporal Map Reveals Dominant Expression Patterns

    Siobhan M. Brady;David A. Orlando;Ji-Young Lee;Jean Y. Wang

  • FMRP targets distinct mRNA sequence elements to regulate protein expression

    Manuel Ascano;Neelanjan Mukherjee;Pradeep Bandaru;Jason B. Miller

  • A viral microRNA functions as an orthologue of cellular miR-155

    Eva Gottwein;Neelanjan Mukherjee;Christoph Sachse;Corina Frenzel

  • Integrative Regulatory Mapping Indicates that the RNA-Binding Protein HuR Couples Pre-mRNA Processing and mRNA Stability

    Neelanjan Mukherjee;David L. Corcoran;Jeffrey D. Nusbaum;Jeffrey D. Nusbaum;David W. Reid

  • Computational analysis of core promoters in the Drosophila genome

    Uwe Ohler;Uwe Ohler;Guo-chun Liao;Heinrich Niemann;Gerald M Rubin

  • The Translational Landscape of the Human Heart

    Sebastiaan van Heesch;Franziska Witte;Valentin Schneider-Lunitz;Jana F. Schulz

  • Gene expression divergence recapitulates the developmental hourglass model

    Alex T. Kalinka;Karolina M. Varga;Karolina M. Varga;Dave T. Gerrard;Stephan Preibisch

  • Detecting actively translated open reading frames in ribosome profiling data

    Lorenzo Calviello;Neelanjan Mukherjee;Emanuel Wyler;Henrik Zauber

  • The viral and cellular microRNA targetome in lymphoblastoid cell lines

    Rebecca L. Skalsky;David L Corcoran;Eva Gottwein;Christopher L. Frank

  • Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.

    Joana P. Bernardes;Neha Mishra;Florian Tran;Thomas Bahmer

  • PARalyzer: definition of RNA binding sites from PAR-CLIP short-read sequence data

    David L Corcoran;Stoyan Georgiev;Neelanjan Mukherjee;Eva Gottwein

  • Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms

    Takashi Mino;Yasuhiro Murakawa;Akira Fukao;Alexis Vandenbon

  • Viral MicroRNA Targetome of KSHV-Infected Primary Effusion Lymphoma Cell Lines

    Eva Gottwein;David L. Corcoran;Neelanjan Mukherjee;Rebecca L. Skalsky

  • Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots

    Ji-Young Lee;Juliette Colinas;Jean Y. Wang;Daniel Mace

  • Translocation of Sickle Cell Erythrocyte MicroRNAs into Plasmodium falciparum Inhibits Parasite Translation and Contributes to Malaria Resistance

    Gregory LaMonte;Nisha Philip;Joseph Reardon;Joshua R. Lacsina

  • The MTE, a new core promoter element for transcription by RNA polymerase II

    Chin Yan Lim;Buyung Santoso;Thomas Boulay;Emily Dong

  • Predicting cell-type-specific gene expression from regions of open chromatin.

    Anirudh Natarajan;Galip Gürkan Yardımcı;Nathan C. Sheffield;Gregory E. Crawford

  • Genome annotation assessment in Drosophila melanogaster

    Martin G. Reese;George Hartzell;Nomi L. Harris;Uwe Ohler

  • High-Resolution Expression Map of the Arabidopsis Root Reveals Alternative Splicing and lincRNA Regulation.

    Song Li;Masashi Yamada;Xinwei Han;Uwe Ohler;Uwe Ohler

Frequent Co-Authors

Philip N. Benfey
Philip N. Benfey Duke University
Markus Landthaler
Markus Landthaler Max Delbrück Center for Molecular Medicine
Matthias Selbach
Matthias Selbach Max Delbrück Center for Molecular Medicine
Thomas Tuschl
Thomas Tuschl Rockefeller University
Markus Hafner
Markus Hafner National Institutes of Health
Heinrich Niemann
Heinrich Niemann University of Erlangen-Nuremberg
Bryan R. Cullen
Bryan R. Cullen Duke University
Nikolaus Rajewsky
Nikolaus Rajewsky Max Delbrück Center for Molecular Medicine
Gregory E. Crawford
Gregory E. Crawford Duke University

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