His Phenotype study focuses on Conditional gene knockout and Penetrance. His research brings together the fields of Phenotype and Conditional gene knockout. In his research, John L. Rinn undertakes multidisciplinary study on Penetrance and Gene. In his works, he conducts interdisciplinary research on Gene and Computational biology. John L. Rinn integrates many fields in his works, including Computational biology and Genetics. His study ties his expertise on CRISPR together with the subject of Genetics. John L. Rinn combines CRISPR and RNA in his studies. John L. Rinn undertakes interdisciplinary study in the fields of RNA and Long non-coding RNA through his works. He undertakes interdisciplinary study in the fields of Endocrinology and Pathology through his research.
John L. Rinn connects Biochemistry with Organic chemistry in his research. In his papers, he integrates diverse fields, such as Organic chemistry and Biochemistry. He performs multidisciplinary study in Genetics and Computational biology in his work. He integrates Computational biology and Gene in his studies. John L. Rinn performs multidisciplinary study in the fields of Gene and Regulation of gene expression via his papers. John L. Rinn undertakes multidisciplinary studies into Endocrinology and Internal medicine in his work. John L. Rinn combines Internal medicine and Endocrinology in his research. He undertakes multidisciplinary studies into Diabetes mellitus and Microangiopathy in his work. His work blends Microangiopathy and Diabetes mellitus studies together.
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Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks
Cole Trapnell;Adam Roberts;Loyal Goff;Loyal Goff;Loyal Goff;Geo Pertea.
Nature Protocols (2012)
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
Rajnish A. Gupta;Nilay R. Shah;Kevin C. Wang;Jeewon Kim.
Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs
John L. Rinn;Michael Kertesz;Jordon K. Wang;Sharon L. Squazzo.
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
Mitchell Guttman;Ido Amit;Manuel Garber;Courtney French.
Genome Regulation by Long Noncoding RNAs
John L. Rinn;Howard Y. Chang.
Annual Review of Biochemistry (2012)
The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
Cole Trapnell;Davide Cacchiarelli;Davide Cacchiarelli;Jonna L Grimsby;Prapti Pokharel.
Nature Biotechnology (2014)
Differential analysis of gene regulation at transcript resolution with RNA-seq
Cole Trapnell;David G Hendrickson;David G Hendrickson;Martin Sauvageau;Martin Sauvageau;Loyal Goff;Loyal Goff.
Nature Biotechnology (2013)
Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
Moran N. Cabili;Cole Trapnell;Cole Trapnell;Loyal Goff;Magdalena J. Koziol;Magdalena J. Koziol.
Genes & Development (2011)
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
Ahmad M. Khalil;Mitchell Guttman;Maite Huarte;Manuel Garber.
Proceedings of the National Academy of Sciences of the United States of America (2009)
The ENCODE (ENCyclopedia of DNA elements) Project
E. A. Feingold;P. J. Good;M. S. Guyer;S. Kamholz.
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