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Genetics and Molecular Biology
USA
2024

D-Index & Metrics

Genetics

D-Index
104
Citations
111644
World Ranking
633
National Ranking
319

Molecular Biology

D-Index
104
Citations
111644
World Ranking
453
National Ranking
254

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in United States Leader Award

Overview

John L. Rinn is affiliated with the University of Colorado Boulder in the United States. Their research work primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions to subfields such as molecular biology, cancer research, infectious diseases, immunology, and modeling and simulation.

Their work covers a range of topics, including:

  • Cancer-related molecular mechanisms research
  • RNA modifications and cancer
  • RNA research and splicing
  • RNA and protein synthesis mechanisms
  • CRISPR and genetic engineering
  • Genomics and chromatin dynamics
  • Epigenetics and DNA methylation

John L. Rinn has numerous publications, frequently contributing to venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature Genetics
  • Genome Biology
  • PLoS ONE

Frequent co-authors in their work include Michael J. Smallegan, Marta Melé, Chiara Gerhardinger, Taeyoung Hwang, and Thomas R. Cech, each collaborating on multiple projects.

Some of their recent papers include:

  • Long Noncoding RNAs: Molecular Modalities to Organismal Functions, 2020, Annual Review of Biochemistry
  • The Sox2 transcription factor binds RNA, 2020, Nature Communications
  • RNA is essential for PRC2 chromatin occupancy and function in human pluripotent stem cells, 2020, Nature Genetics
  • Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics, 2020, Cell
  • Long non-coding RNAs: definitions, functions, challenges and recommendations, 2023, Nature Reviews Molecular Cell Biology

Best Publications

  • Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

    Cole Trapnell;Adam Roberts;Loyal Goff;Loyal Goff;Loyal Goff;Geo Pertea

  • Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

    Rajnish A. Gupta;Nilay R. Shah;Kevin C. Wang;Jeewon Kim

  • The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

    Cole Trapnell;Davide Cacchiarelli;Davide Cacchiarelli;Jonna L Grimsby;Prapti Pokharel

  • Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs

    John L. Rinn;Michael Kertesz;Jordon K. Wang;Sharon L. Squazzo

  • Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

    Mitchell Guttman;Ido Amit;Manuel Garber;Courtney French

  • Genome Regulation by Long Noncoding RNAs

    John L. Rinn;Howard Y. Chang

  • Differential analysis of gene regulation at transcript resolution with RNA-seq

    Cole Trapnell;David G Hendrickson;David G Hendrickson;Martin Sauvageau;Martin Sauvageau;Loyal Goff;Loyal Goff

  • Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

    Moran N. Cabili;Cole Trapnell;Cole Trapnell;Loyal Goff;Magdalena J. Koziol;Magdalena J. Koziol

  • The multilayered complexity of ceRNA crosstalk and competition

    Yvonne Tay;John L Rinn;Pier Paolo Pandolfi

  • The ENCODE (ENCyclopedia of DNA elements) Project

    E. A. Feingold;P. J. Good;M. S. Guyer;S. Kamholz

  • Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

    Ahmad M. Khalil;Mitchell Guttman;Maite Huarte;Manuel Garber

  • Expanded encyclopaedias of DNA elements in the human and mouse genomes

    Jill E. Moore;Michael J. Purcaro;Henry E. Pratt;Charles B. Epstein

  • Modular regulatory principles of large non-coding RNAs

    Mitchell Guttman;John L. Rinn;John L. Rinn

  • A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

    Maite Huarte;Mitchell Guttman;Mitchell Guttman;David Feldser;Manuel Garber

  • lincRNAs act in the circuitry controlling pluripotency and differentiation

    Mitchell Guttman;Julie Donaghey;Bryce W. Carey;Manuel Garber

  • Improving RNA-Seq expression estimates by correcting for fragment bias

    Adam B Roberts;Cole Trapnell;Cole Trapnell;Julie Donaghey;John L Rinn;John L Rinn

  • Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs

    Mitchell Guttman;Manuel Garber;Joshua Z Levin;Julie Donaghey

  • Global Identification of Human Transcribed Sequences with Genome Tiling Arrays

    Paul Bertone;Viktor Stolc;Viktor Stolc;Thomas E. Royce;Joel S. Rozowsky

  • Basset: learning the regulatory code of the accessible genome with deep convolutional neural networks

    David R. Kelley;Jasper Snoek;John L. Rinn

  • Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

    Sabine Loewer;Moran N Cabili;Moran N Cabili;Mitchell Guttman;Yuin-Han Loh

Frequent Co-Authors

Loyal A. Goff
Loyal A. Goff Johns Hopkins University School of Medicine
Eric S. Lander
Eric S. Lander Broad Institute
Alexander Meissner
Alexander Meissner Max Planck Institute for Molecular Genetics
Howard Y. Chang
Howard Y. Chang Amgen (United States)
Aviv Regev
Aviv Regev Genentech
Cole Trapnell
Cole Trapnell University of Washington
Mitchell Guttman
Mitchell Guttman California Institute of Technology
James Lee
James Lee The Francis Crick Institute
Tarjei S. Mikkelsen
Tarjei S. Mikkelsen Arsenal Biosciences (United States)
Manuel Garber
Manuel Garber University of Massachusetts Chan Medical School

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