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D-Index & Metrics

Biology and Biochemistry

D-Index
45
Citations
31681
World Ranking
19019
National Ranking
7763

Overview

Loyal A. Goff is affiliated with Johns Hopkins University School of Medicine in the United States. Their research predominantly falls within the fields of Biochemistry, Genetics, and Molecular Biology, with a significant focus on Molecular Biology, Immunology, Cellular and Molecular Neuroscience, Neurology, and Developmental Neuroscience.

The scientist's work covers several main topics, including:

  • Single-cell and spatial transcriptomics
  • Neurogenesis and neuroplasticity mechanisms
  • Cell image analysis techniques
  • Retinal development and disorders
  • Gene expression and cancer classification
  • RNA research and splicing
  • Congenital gastrointestinal and neural anomalies

Among the recent publications authored or coauthored by Loyal A. Goff are the following:

  • "Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development," 2020, Developmental Cell
  • "Psychedelics reopen the social reward learning critical period," 2023, Nature
  • "Universal prediction of cell-cycle position using transfer learning," 2022, Genome Biology
  • "Prenatal immune stress blunts microglia reactivity, impairing neurocircuitry," 2022, Nature
  • "projectR: an R/Bioconductor package for transfer learning via PCA, NMF, correlation and clustering," 2020, Bioinformatics

Frequent coauthors of Loyal A. Goff include:

  • Genevieve Stein-O'Brien
  • Jared Slosberg
  • Elizabeth Vincent
  • Elana J. Fertig
  • Gül Dölen

The scientist's publications are commonly found in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Genome Biology
  • Cell Reports
  • eLife

Best Publications

  • Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

    Cole Trapnell;Adam Roberts;Loyal Goff;Loyal Goff;Loyal Goff;Geo Pertea

  • Differential analysis of gene regulation at transcript resolution with RNA-seq

    Cole Trapnell;David G Hendrickson;David G Hendrickson;Martin Sauvageau;Martin Sauvageau;Loyal Goff;Loyal Goff

  • Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

    Moran N. Cabili;Cole Trapnell;Cole Trapnell;Loyal Goff;Magdalena J. Koziol;Magdalena J. Koziol

  • Multiple knockout mouse models reveal lincRNAs are required for life and brain development

    Martin Sauvageau;Martin Sauvageau;Loyal A Goff;Loyal A Goff;Loyal A Goff;Simona Lodato;Simona Lodato;Boyan Bonev;Boyan Bonev

  • Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre

    Ezgi Hacisuleyman;Loyal A Goff;Cole Trapnell;Adam Williams

  • Single cell RNA-Seq analysis of retinal development identifies NFI factors as regulating mitotic exit and late-born cell specification.

    Brian S. Clark;Genevieve L. Stein-O’Brien;Fion Shiau;Gabrielle H. Cannon

  • DNMT1-interacting RNAs block gene-specific DNA methylation

    Annalisa Di Ruscio;Alexander K. Ebralidze;Touati Benoukraf;Giovanni Amabile

  • Long noncoding RNAs regulate adipogenesis

    Lei Sun;Loyal A. Goff;Cole Trapnell;Ryan Alexander

  • Differential regulation of microRNA stability

    Sophie Bail;Mavis Swerdel;Hudan Liu;Xinfu Jiao

  • Linear models enable powerful differential activity analysis in massively parallel reporter assays.

    Leslie Myint;Dimitrios G. Avramopoulos;Loyal A. Goff;Kasper D. Hansen

  • DeCoN: Genome-wide Analysis of In Vivo Transcriptional Dynamics during Pyramidal Neuron Fate Selection in Neocortex

    Bradley J. Molyneaux;Loyal A. Goff;Loyal A. Goff;Loyal A. Goff;Andrea C. Brettler;Hsu Hsin Chen

  • Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development

    Yufeng Lu;Fion Shiau;Wenyang Yi;Suying Lu

  • The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan

    Jonathan J. Kotzin;Sean P. Spencer;Sean P. Spencer;Sam J. McCright;Dinesh B. Uthaya Kumar

  • The MicroRNA miR-181 Is a Critical Cellular Metabolic Rheostat Essential for NKT Cell Ontogenesis and Lymphocyte Development and Homeostasis

    Jorge Henao-Mejia;Adam Williams;Loyal A. Goff;Loyal A. Goff;Matthew Staron

  • Enter the Matrix: Factorization Uncovers Knowledge from Omics

    Genevieve L. Stein-O’Brien;Raman Arora;Aedin C. Culhane;Alexander V. Favorov

  • MicroRNA expression pattern of undifferentiated and differentiated human embryonic stem cells.

    Uma Lakshmipathy;Brad Love;Loyal A. Goff;Rebecka Jörnsten

  • Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells.

    Mark F Sabbagh;Jacob S Heng;Chongyuan Luo;Rosa G Castanon

  • Linking RNA biology to lncRNAs

    Loyal A. Goff;John L. Rinn

  • Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain.

    Loyal A. Goff;Loyal A. Goff;Abigail F. Groff;Abigail F. Groff;Martin Sauvageau;Martin Sauvageau;Zachary Trayes-Gibson

  • Decomposing Cell Identity for Transfer Learning across Cellular Measurements, Platforms, Tissues, and Species

    Genevieve L. Stein-O’Brien;Brian S. Clark;Thomas Sherman;Cristina Zibetti

Frequent Co-Authors

John L. Rinn
John L. Rinn University of Colorado Boulder
Ronald P. Hart
Ronald P. Hart Rutgers, The State University of New Jersey
Kasper D. Hansen
Kasper D. Hansen Johns Hopkins University
Cole Trapnell
Cole Trapnell University of Washington
Richard A. Flavell
Richard A. Flavell Yale University
Paola Arlotta
Paola Arlotta Harvard University
Jeremy Nathans
Jeremy Nathans Johns Hopkins University School of Medicine
Donald J. Zack
Donald J. Zack Johns Hopkins University School of Medicine
Jiang Qian
Jiang Qian Johns Hopkins University School of Medicine

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