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Neuroscience

D-Index
53
Citations
19213
World Ranking
5010
National Ranking
2245

Overview

Paola Arlotta is affiliated with Harvard University in the United States and specializes in research within biochemistry, genetics, molecular biology, and neuroscience. Their work spans specific subfields including molecular biology, developmental neuroscience, neurology, cellular and molecular neuroscience, and biophysics.

Their research covers a range of main topics, such as:

  • Single-cell and spatial transcriptomics
  • Pluripotent stem cells research
  • Neurogenesis and neuroplasticity mechanisms
  • Neuroinflammation and neurodegeneration mechanisms
  • RNA research and splicing
  • CRISPR and genetic engineering
  • Cell image analysis techniques

Arlotta's recent publications include:

  • Highly sensitive spatial transcriptomics at near-cellular resolution with Slide-seqV2, 2020, Nature Biotechnology
  • Molecular logic of cellular diversification in the mouse cerebral cortex, 2021, Nature
  • Autism genes converge on asynchronous development of shared neuron classes, 2022, Nature
  • In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes, 2020, Science
  • A nomenclature consensus for nervous system organoids and assembloids, 2022, Nature

Frequent co-authors collaborating with Arlotta include:

  • Joshua Z. Levin
  • Daniela J. Di Bella
  • Aviv Regev
  • Kwanho Kim
  • Juliana Brown

Their publications are often featured in prominent scientific journals. The most common venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Science
  • Nature Neuroscience
  • Development

Best Publications

  • Neuronal subtype specification in the cerebral cortex.

    Bradley J. Molyneaux;Paola Arlotta;Joao R. L. Menezes;Joao R. L. Menezes;Jeffrey D. Macklis

  • Neuronal Subtype-Specific Genes that Control Corticospinal Motor Neuron Development In Vivo

    Paola Arlotta;Bradley J. Molyneaux;Jinhui Chen;Jun Inoue

  • Cell diversity and network dynamics in photosensitive human brain organoids

    Giorgia Quadrato;Giorgia Quadrato;Tuan Nguyen;Tuan Nguyen;Evan Z. Macosko;Evan Z. Macosko;John L. Sherwood;John L. Sherwood

  • Highly sensitive spatial transcriptomics at near-cellular resolution with Slide-seqV2.

    Robert R. Stickels;Robert R. Stickels;Evan Murray;Pawan Kumar;Jilong Li

  • Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

    Feng Zhang;Le Cong;Le Cong;Simona Lodato;Sriram Kosuri;Sriram Kosuri

  • Individual brain organoids reproducibly form cell diversity of the human cerebral cortex

    Silvia Velasco;Amanda J. Kedaigle;Amanda J. Kedaigle;Sean K. Simmons;Allison Nash;Allison Nash

  • Multiple knockout mouse models reveal lincRNAs are required for life and brain development

    Martin Sauvageau;Martin Sauvageau;Loyal A Goff;Loyal A Goff;Loyal A Goff;Simona Lodato;Simona Lodato;Boyan Bonev;Boyan Bonev

  • Distinct profiles of myelin distribution along single axons of pyramidal neurons in the neocortex

    Giulio Srubek Tomassy;Daniel R. Berger;Daniel R. Berger;Hsu-Hsin Chen;Narayanan Kasthuri

  • Fezl Is Required for the Birth and Specification of Corticospinal Motor Neurons

    Bradley J. Molyneaux;Paola Arlotta;Tustomu Hirata;Masahiko Hibi

  • Molecular logic of cellular diversification in the mouse cerebral cortex.

    Daniela J. Di Bella;Daniela J. Di Bella;Ehsan Habibi;Ehsan Habibi;Robert R. Stickels;Gabriele Scalia

  • Ctip2 Controls the Differentiation of Medium Spiny Neurons and the Establishment of the Cellular Architecture of the Striatum

    Paola Arlotta;Bradley John Molyneaux;Denis Jabaudon;Yutaka Yoshida

  • Generating neuronal diversity in the mammalian cerebral cortex.

    Simona Lodato;Paola Arlotta

  • SOX5 Controls the Sequential Generation of Distinct Corticofugal Neuron Subtypes

    Tina Lai;Denis Jabaudon;Bradley J. Molyneaux;Eiman Azim

  • Voltage imaging and optogenetics reveal behaviour-dependent changes in hippocampal dynamics

    Yoav Adam;Jeong J. Kim;Shan Lou;Yongxin Zhao

  • DeCoN: Genome-wide Analysis of In Vivo Transcriptional Dynamics during Pyramidal Neuron Fate Selection in Neocortex

    Bradley J. Molyneaux;Loyal A. Goff;Loyal A. Goff;Loyal A. Goff;Andrea C. Brettler;Hsu Hsin Chen

  • The promises and challenges of human brain organoids as models of neuropsychiatric disease.

    Giorgia Quadrato;Juliana Brown;Paola Arlotta

  • In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes.

    Xin Jin;Sean K. Simmons;Amy Guo;Ashwin S. Shetty;Ashwin S. Shetty

  • Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo

    Caroline Rouaux;Paola Arlotta

  • Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission

    Ralda Nehme;Ralda Nehme;Emanuela Zuccaro;Emanuela Zuccaro;Sulagna Dia Ghosh;Sulagna Dia Ghosh;Chenchen Li

  • Excitatory Projection Neuron Subtypes Control the Distribution of Local Inhibitory Interneurons in the Cerebral Cortex

    Simona Lodato;Caroline Rouaux;Kathleen B. Quast;Chanati Jantrachotechatchawan

  • Novel Subtype-Specific Genes Identify Distinct Subpopulations of Callosal Projection Neurons

    Bradley John Molyneaux;Paola Arlotta;Ryan Marie Fame;Jessica Linn MacDonald

Frequent Co-Authors

Jeffrey D. Macklis
Jeffrey D. Macklis Harvard University
John L. Rinn
John L. Rinn University of Colorado Boulder
Joshua Z. Levin
Joshua Z. Levin Broad Institute
Aviv Regev
Aviv Regev Genentech
Alexander Meissner
Alexander Meissner Max Planck Institute for Molecular Genetics
Kasper Lage
Kasper Lage Harvard University
Elise B. Robinson
Elise B. Robinson Broad Institute

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