What is he best known for?
The fields of study he is best known for:
Charles A. Gersbach spends much of his time researching Genetics, CRISPR, Genome editing, Cell biology and Regulation of gene expression.
His work deals with themes such as Chromatin, Transcription, Epigenetics and Computational biology, which intersect with CRISPR.
His study in Genome editing is interdisciplinary in nature, drawing from both Duchenne muscular dystrophy and Dystrophin.
His Cell biology study combines topics from a wide range of disciplines, such as Transcription factor, Transactivation, Cytoskeleton and Endogeny.
In Regulation of gene expression, Charles A. Gersbach works on issues like Enhancer, which are connected to STAT6.
While the research belongs to areas of Transcription activator-like effector nuclease, Charles A. Gersbach spends his time largely on the problem of Zinc finger nuclease, intersecting his research to questions surrounding Non-homologous end joining and DNA.
His most cited work include:
- ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering (2325 citations)
- Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers (1029 citations)
- RNA-guided gene activation by CRISPR-Cas9-based transcription factors (877 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include CRISPR, Cell biology, Computational biology, Genetics and Genome editing.
Charles A. Gersbach works mostly in the field of CRISPR, limiting it down to topics relating to Epigenome editing and, in certain cases, Epigenomics and Epigenome, as a part of the same area of interest.
Charles A. Gersbach has included themes like Transcription, Regulation of gene expression, Transcription factor and Gene expression in his Cell biology study.
His Computational biology research incorporates themes from Genome, Genetic enhancement and Guide RNA.
In general Genetics, his work in Human genome, Zinc finger, DNA and Gene targeting is often linked to Protein engineering linking many areas of study.
He combines subjects such as Duchenne muscular dystrophy and DNA repair with his study of Genome editing.
He most often published in these fields:
- CRISPR (36.52%)
- Cell biology (34.27%)
- Computational biology (33.71%)
What were the highlights of his more recent work (between 2018-2021)?
- CRISPR (36.52%)
- Computational biology (33.71%)
- Cell biology (34.27%)
In recent papers he was focusing on the following fields of study:
His main research concerns CRISPR, Computational biology, Cell biology, Genome editing and Gene.
Charles A. Gersbach connects CRISPR with Fusion protein in his study.
His Computational biology research incorporates elements of Genome engineering, Genome, Human genome, Cas9 and Transcription factor.
His Cas9 study combines topics in areas such as Epigenome editing, Epigenetics and DNA repair.
Charles A. Gersbach has researched Cell biology in several fields, including Cell, Transcription and Induced pluripotent stem cell.
His study explores the link between Genome editing and topics such as Duchenne muscular dystrophy that cross with problems in Pathology.
Between 2018 and 2021, his most popular works were:
- The next generation of CRISPR-Cas technologies and applications. (295 citations)
- Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy. (133 citations)
- Increasing the specificity of CRISPR systems with engineered RNA secondary structures. (103 citations)
In his most recent research, the most cited papers focused on:
CRISPR, Computational biology, Cell biology, Cas9 and Gene are his primary areas of study.
A large part of his CRISPR studies is devoted to Genome editing.
His Computational biology research includes themes of Duchenne muscular dystrophy and Genome.
His studies deal with areas such as Acetylation and Gene expression as well as Cell biology.
His Guide RNA and Genome engineering study in the realm of Cas9 interacts with subjects such as Computer science.
His research in Gene is mostly focused on Epigenetics.
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