World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
43
Citations
17008
World Ranking
4272
National Ranking
1843

Overview

Lingyun Song is affiliated with Duke University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on molecular biology, artificial intelligence, genetics, infectious diseases, and epidemiology.

Their work concentrates on several main research topics, including:

  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • Tuberculosis Research and Epidemiology
  • Congenital heart defects research
  • RNA Research and Splicing
  • Gene expression and cancer classification
  • MicroRNA in disease regulation

Lingyun Song has contributed to publications in several venues, reflecting their multidisciplinary interests. Frequent publication venues include:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Development
  • Scientific Data

Notable recent papers authored or co-authored by Lingyun Song feature a range of topics related to gene regulation and brain disorders:

  • Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions, 2020, Scientific Data
  • Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders, 2021, Nature Communications
  • Identification and requirements of enhancers that direct gene expression during zebrafish fin regeneration, 2020, Development
  • Functional annotation of rare structural variation in the human brain, 2020, Nature Communications
  • Enhancer selection dictates gene expression responses in remote organs during tissue regeneration, 2022, Nature Cell Biology

Lingyun Song collaborates frequently with a select group of researchers, including:

  • Gregory E. Crawford
  • Alexias Safi
  • Yilin Zhang
  • Feng Sun
  • Shijia Ge

Best Publications

  • The accessible chromatin landscape of the human genome

    Robert E. Thurman;Eric Rynes;Richard Humbert;Jeff Vierstra

  • An integrated encyclopedia of DNA elements in the human genome

    Ian Dunham;Anshul Kundaje;Shelley F. Aldred;Patrick J. Collins

  • A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

    Richard M. Myers;John Stamatoyannopoulos;Michael Snyder;Ian Dunham

  • Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

    Pratiksha I Thakore;Anthony M D'Ippolito;Lingyun Song;Alexias Safi

  • DNase-seq: A High-Resolution Technique for Mapping Active Gene Regulatory Elements across the Genome from Mammalian Cells

    Lingyun Song;Gregory E. Crawford

  • Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity

    Lingyun Song;Zhancheng Zhang;Linda L. Grasfeder;Alan P. Boyle

  • Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

    Alexander Gusev;Alexander Gusev;Nicholas Mancuso;Hyejung Won;Maria Kousi

  • CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

    Tyler S Klann;Joshua B Black;Malathi Chellappan;Alexias Safi

  • High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells

    Alan P. Boyle;Lingyun Song;Bum Kyu Lee;Darin London

  • Heritable Individual-Specific and Allele-Specific Chromatin Signatures in Humans

    Ryan McDaniell;Bum Kyu Lee;Lingyun Song;Zheng Liu

  • Transcriptome and epigenome landscape of human cortical development modeled in organoids

    Anahita Amiri;Gianfilippo Coppola;Soraya Scuderi;Feinan Wu

  • Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns

    Michael P. Schnetz;Cynthia F. Bartels;Kuntal Shastri;Dheepa Balasubramanian

  • Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions

    Nathan C. Sheffield;Robert E. Thurman;Lingyun Song;Alexias Safi

  • CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder.

    Gabriel E. Hoffman;Jaroslav Bendl;Georgios Voloudakis;Kelsey S. Montgomery

  • Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci

    Michael L. Stitzel;Praveen Sethupathy;Daniel S. Pearson;Peter S. Chines

  • Site-specific silencing of regulatory elements as a mechanism of X-inactivation

    J. Mauro Calabrese;Wei Sun;Lingyun Song;Joshua W. Mugford

  • Effects of sequence variation on differential allelic transcription factor occupancy and gene expression

    Timothy E. Reddy;Jason Gertz;Florencia Pauli;Katerina S. Kucera

  • Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome.

    Christopher M. Vockley;Anthony M. D’Ippolito;Ian C. McDowell;William H. Majoros

  • Epigenomic comparison reveals activation of "seed" enhancers during transition from naive to primed pluripotency.

    Daniel C. Factor;Olivia Corradin;Gabriel E. Zentner;Alina Saiakhova

  • Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia

    Julien Bryois;Melanie E. Garrett;Lingyun Song;Alexias Safi

Frequent Co-Authors

Gregory E. Crawford
Gregory E. Crawford Duke University
Terrence S. Furey
Terrence S. Furey University of North Carolina at Chapel Hill
Charles A. Gersbach
Charles A. Gersbach Duke University
Vishwanath R. Iyer
Vishwanath R. Iyer The University of Texas at Austin
Allison E. Ashley-Koch
Allison E. Ashley-Koch Duke University
Patrick F. Sullivan
Patrick F. Sullivan University of North Carolina at Chapel Hill
Ewan Birney
Ewan Birney European Molecular Biology Laboratory
Jason D. Lieb
Jason D. Lieb University of Chicago
Vahram Haroutunian
Vahram Haroutunian Icahn School of Medicine at Mount Sinai
Melanie Ehrlich
Melanie Ehrlich Tulane University

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