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Biology and Biochemistry

D-Index
87
Citations
33326
World Ranking
2790
National Ranking
1438

Overview

Panos Roussos is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research work primarily spans biochemistry, genetics, and molecular biology, with significant contributions in molecular biology, genetics, neurology, physiology, and biological psychiatry.

The scientist's main areas of study include genetic associations and epidemiology, epigenetics and DNA methylation, single-cell and spatial transcriptomics, bioinformatics and genomic networks, neuroinflammation and neurodegeneration mechanisms, genomics and chromatin dynamics, and Alzheimer's disease research and treatments.

Among the diverse topics covered in their publications are:

  • Genetic Associations and Epidemiology
  • Epigenetics and DNA Methylation
  • Single-cell and spatial transcriptomics
  • Bioinformatics and Genomic Networks
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Genomics and Chromatin Dynamics
  • Alzheimer's disease research and treatments

Roussos has coauthored papers extensively with the following researchers:

  • John F. Fullard
  • Jaroslav Bendl
  • Gabriel E. Hoffman
  • Georgios Voloudakis
  • Kiran Girdhar

Their publishing record includes frequent contributions to several scientific journals, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • European Neuropsychopharmacology
  • Biological Psychiatry
  • Nature Communications
  • Nature Genetics

Recent notable publications by Panos Roussos include:

  • Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains, 2023, Nature Genetics
  • Dream: powerful differential expression analysis for repeated measures designs, 2020, Bioinformatics
  • Non-cell-autonomous disruption of nuclear architecture as a potential cause of COVID-19-induced anosmia, 2022, Cell
  • Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses, 2023, Nature Medicine
  • Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes, 2021, Nature Communications

Best Publications

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

    Ditte Demontis;Ditte Demontis;Raymond K Walters;Raymond K Walters;Joanna Martin;Joanna Martin;Joanna Martin;Manuel Mattheisen

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • De novo mutations in schizophrenia implicate synaptic networks

    Menachem Fromer;Andrew Pocklington;David Kavanagh;Hywel John Williams

  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    Eli A. Stahl;Eli A. Stahl;Gerome Breen;Andreas J. Forstner;Andrew McQuillin

  • A polygenic burden of rare disruptive mutations in schizophrenia

    Shaun M Purcell;Jennifer L Moran;Menachem Fromer;Douglas Ruderfer

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

    Niamh Mullins;Andreas J. Forstner;Andreas J. Forstner;Andreas J. Forstner;Kevin S. O'Connell;Kevin S. O'Connell;Brandon Coombes

  • Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

    Jeanne E Savage;Philip R Jansen;Philip R Jansen;Sven Stringer;Kyoko Watanabe

  • Gene expression elucidates functional impact of polygenic risk for schizophrenia

    Menachem Fromer;Panos Roussos;Solveig K. Sieberts;Jessica S. Johnson

  • Comprehensive functional genomic resource and integrative model for the human brain

    Daifeng Wang;Daifeng Wang;Shuang Liu;Jonathan Warrell;Hyejung Won

  • Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

    Christian R Marshall;Daniel P Howrigan;Daniel P Howrigan;Daniele Merico;Bhooma Thiruvahindrapuram

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

    Gail Davies;Max Lam;Sarah E. Harris;Joey W. Trampush

  • Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

    Alexander Gusev;S. Hong Lee;Gosia Trynka;Hilary Finucane

  • The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.

    Minghui Wang;Noam D. Beckmann;Panos Roussos;Erming Wang

  • Brain Cell Type Specific Gene Expression and Co-expression Network Architectures

    Andrew T. McKenzie;Minghui Wang;Mads E. Hauberg;John F. Fullard

  • The PsychENCODE project

    Schahram Akbarian;Chunyu Liu;James A Knowles;Flora M Vaccarino

  • Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases.

    Oscar Franzén;Raili Ermel;Raili Ermel;Ariella Cohain;Nicholas K. Akers

  • Myelination, Oligodendrocytes, and Serious Mental Illness

    V. Haroutunian;V. Haroutunian;P. Katsel;P. Roussos;P. Roussos;K. L. Davis

Frequent Co-Authors

Aarno Palotie
Aarno Palotie University of Helsinki
Ole A. Andreassen
Ole A. Andreassen Oslo University Hospital
Panos Bitsios
Panos Bitsios University of Crete
Ingrid Melle
Ingrid Melle University of Oslo
Vahram Haroutunian
Vahram Haroutunian Icahn School of Medicine at Mount Sinai
Srdjan Djurovic
Srdjan Djurovic Oslo University Hospital
Johan G. Eriksson
Johan G. Eriksson National University of Singapore
Katherine E. Burdick
Katherine E. Burdick Brigham and Women's Hospital
Derek W. Morris
Derek W. Morris University of Galway
Gary Donohoe
Gary Donohoe University of Galway

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