World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
78
Citations
20289
World Ranking
1300
National Ranking
575

Overview

Dennis E. Kyle is affiliated with the University of Georgia in the United States and has a substantial research output focused primarily on the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Public Health, Environmental and Occupational Health, Endocrinology, Molecular Biology, Immunology, and Infectious Diseases.

Their research interests are concentrated on key topics such as:

  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Legionella and Acanthamoeba research
  • Vibrio bacteria research studies
  • Bacterial biofilms and quorum sensing
  • Heme Oxygenase-1 and Carbon Monoxide
  • Drug Transport and Resistance Mechanisms

Dennis E. Kyle has contributed extensively to scholarly publications in venues including:

  • bioRxiv (Cold Spring Harbor Laboratory), with 20 publications
  • Frontiers in Microbiology, with 4 publications
  • Antimicrobial Agents and Chemotherapy, with 3 publications
  • ACS Infectious Diseases, with 3 publications
  • Research Square (Research Square), with 3 publications

Their recent papers illustrate a focus on infectious diseases and parasitology, including:

  • "Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples" (2023), published in Wellcome Open Research
  • "Discovery of repurposing drug candidates for the treatment of diseases caused by pathogenic free-living amoebae" (2020), published in PLoS neglected tropical diseases
  • "Single-cell RNA profiling of Plasmodium vivax-infected hepatocytes reveals parasite- and host-specific transcriptomic signatures and therapeutic targets" (2022), published in Frontiers in Cellular and Infection Microbiology
  • "Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3" (2020), published in Cell chemical biology
  • "Discovery of Anti-Amoebic Inhibitors from Screening the MMV Pandemic Response Box on Balamuthia mandrillaris, Naegleria fowleri, and Acanthamoeba castellanii" (2020), published in Pathogens

Dennis E. Kyle frequently collaborates with a number of researchers, sharing multiple publications with:

  • Steven P. Maher, with 27 coauthored works
  • Amélie Vantaux, with 19 coauthored works
  • Benoît Witkowski, with 19 coauthored works
  • Justine C. Shiau, with 16 coauthored works
  • Christopher A. Rice, with 14 coauthored works

Best Publications

  • Malaria: progress, perils, and prospects for eradication

    Brian M. Greenwood;David A. Fidock;Dennis E. Kyle;Stefan H.I. Kappe

  • Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum.

    S. J. Foote;D. E. Kyle;R. K. Martin;A. M. J. Oduola

  • Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance

    Donald J. Krogstad;Ilya Y. Gluzman;Dennis E. Kyle;Ayoade M. J. Oduola

  • Evidence for the shikimate pathway in apicomplexan parasites

    Fiona Roberts;Fiona Roberts;Craig W. Roberts;Jennifer J. Johnson;Dennis E. Kyle

  • Clinical Studies of Atovaquone, Alone or in Combination with other Antimalarial Drugs, for Treatment of Acute Uncomplicated Malaria in Thailand

    S Looareesuwan;C Viravan;H K Webster;D E Kyle

  • A novel multiple-stage antimalarial agent that inhibits protein synthesis

    Beatriz Baragaña;Irene Hallyburton;Marcus C. S. Lee;Marcus C. S. Lee;Neil R. Norcross

  • Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

    Wesley C. Van Voorhis;John H. Adams;Roberto Adelfio;Roberto Adelfio;Vida Ahyong

  • Genetic Diversity of Plasmodium falciparum Histidine-Rich Protein 2 (PfHRP2) and Its Effect on the Performance of PfHRP2-Based Rapid Diagnostic Tests

    Joanne Baker;James McCarthy;Michelle Gatton;Dennis E. Kyle

  • Amplification of pfmdr1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand

    Craig M. Wilson;Sarah K. Volkman;Sodsri Thaithong;Roger K. Martin

  • Cardiac effects of antimalarial treatment with halofantrine

    F. Nosten;F. O. Ter Kuile;C. Luxemburger;C. Woodrow

  • Artemisone—A Highly Active Antimalarial Drug of the Artemisinin Class†

    Richard K. Haynes;Burkhard Fugmann;Jörg Stetter;Karl Rieckmann

  • Reversal of chloroquine resistance in malaria parasite Plasmodium falciparum by desipramine.

    Alan J. Bitonti;Albert Sjoerdsma;Peter P. McCann;Dennis E. Kyle

  • The epidemiology of malaria in a Karen population on the western border of Thailand

    C. Luxemburger;Kyaw Lay Thwai;N.J. White;H.K. Webster

  • Quinolone-3-Diarylethers: A New Class of Antimalarial Drug

    Aaron Nilsen;Alexis N. LaCrue;Karen L. White;Isaac P. Forquer

  • Artemisinin-induced dormancy in Plasmodium falciparum: duration, recovery rates, and implications in treatment failure.

    Franka Teuscher;Michelle L. Gatton;Nanhua Chen;Jennifer Peters

  • (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium

    María Belén Jiménez-Díaz;Daniel Ebert;Yandira Salinas;Anupam Pradhan

  • Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I.

    Rima McLeod;Stephen P Muench;John B Rafferty;Dennis E Kyle

  • Evolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South America.

    Rajeev K. Mehlotra;Hisashi Fujioka;Paul D. Roepe;Omar Janneh

  • The shikimate pathway and its branches in apicomplexan parasites.

    Craig W. Roberts;Fiona Roberts;Russell E. Lyons;Michael J. Kirisits

  • Randomised double-blind placebo-controlled trial of SPf66 malaria vaccine in children in northwestern Thailand

    F Nosten;C Luxemburger;D E Kyle;W R Ballou

Frequent Co-Authors

Wilbur K. Milhous
Wilbur K. Milhous Clemson University
Bill J. Baker
Bill J. Baker University of South Florida
Nicholas J. White
Nicholas J. White Mahidol University
François Nosten
François Nosten MORU Mahidol Oxford Tropical Medicine Research Unit
Dyann F. Wirth
Dyann F. Wirth Harvard University
Sornchai Looareesuwan
Sornchai Looareesuwan Mahidol University
Michelle L. Gatton
Michelle L. Gatton Queensland University of Technology
David A. Fidock
David A. Fidock Columbia University
Craig W. Roberts
Craig W. Roberts University of Strathclyde
Rima McLeod
Rima McLeod University of Chicago

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