D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 74 Citations 16,938 231 World Ranking 977 National Ranking 446

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Organic chemistry

Dennis E. Kyle mostly deals with Plasmodium falciparum, Malaria, Pharmacology, Virology and Drug resistance. The Plasmodium falciparum study combines topics in areas such as Genetics, Chloroquine and Drug discovery. The study incorporates disciplines such as Internal medicine and Protozoa in addition to Malaria.

His studies deal with areas such as Artesunate, Artemisinin, Dihydroartemisinin and In vivo as well as Pharmacology. His Virology research is multidisciplinary, incorporating elements of Antibacterial agent, DHPS, Sulfadoxine/pyrimethamine, Sulfadoxine and Apicomplexa. His work on Halofantrine as part of general Mefloquine study is frequently connected to Resistance mutation, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.

His most cited work include:

  • Malaria: progress, perils, and prospects for eradication (544 citations)
  • Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. (519 citations)
  • Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance (454 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Plasmodium falciparum, Malaria, Pharmacology, Virology and Drug resistance. His Plasmodium falciparum research focuses on subjects like Chloroquine, which are linked to Verapamil. His work in Malaria addresses issues such as Drug discovery, which are connected to fields such as Naegleria fowleri and Microbiology.

His research in Pharmacology intersects with topics in Quinine, Artesunate and In vivo. His In vivo study incorporates themes from In vitro and Plasmodium berghei. As part of his studies on Virology, Dennis E. Kyle often connects relevant areas like Multiple drug resistance.

He most often published in these fields:

  • Plasmodium falciparum (51.50%)
  • Malaria (37.97%)
  • Pharmacology (34.21%)

What were the highlights of his more recent work (between 2017-2021)?

  • Microbiology (12.03%)
  • Malaria (37.97%)
  • Naegleria fowleri (6.02%)

In recent papers he was focusing on the following fields of study:

Microbiology, Malaria, Naegleria fowleri, Drug discovery and Virology are his primary areas of study. His research in Malaria focuses on subjects like Immune system, which are connected to Secretion. His study on Naegleria fowleri also encompasses disciplines like

  • Drug that connect with fields like Chloroquine, Chloroquine resistance and Malaria elimination,
  • Phenotypic screening together with Miltefosine.

His Virology research includes elements of Aquaporin 3, Parasitology, Plasmodium, Host and Plasmodium vivax. His Plasmodium vivax study is concerned with Plasmodium falciparum in general. Dennis E. Kyle merges Plasmodium falciparum with Geranylgeranyl pyrophosphate in his research.

Between 2017 and 2021, his most popular works were:

  • A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum (56 citations)
  • A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum (56 citations)
  • Open-source discovery of chemical leads for next-generation chemoprotective antimalarials (48 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Organic chemistry

Dennis E. Kyle mainly focuses on Malaria, Pharmacology, Plasmodium falciparum, Virology and Drug discovery. His work blends Malaria and Systematic evolution of ligands by exponential enrichment studies together. He interconnects Phenotype, Symptomatic relief, Parasitemia and Chemoprotective in the investigation of issues within Pharmacology.

The concepts of his Plasmodium falciparum study are interwoven with issues in Natural product, In vitro and In vivo. His study on Cryptosporidium parvum is often connected to LYSYL-tRNA SYNTHETASE as part of broader study in Virology. His Drug discovery study integrates concerns from other disciplines, such as Ion homeostasis, Parasite load, Immune system, Plasmodium vivax and Antibody.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Malaria: progress, perils, and prospects for eradication

Brian M. Greenwood;David A. Fidock;Dennis E. Kyle;Stefan H.I. Kappe.
Journal of Clinical Investigation (2008)

953 Citations

Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum.

S. J. Foote;D. E. Kyle;R. K. Martin;A. M. J. Oduola.
Nature (1990)

743 Citations

Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance

Donald J. Krogstad;Ilya Y. Gluzman;Dennis E. Kyle;Ayoade M. J. Oduola.
Science (1987)

731 Citations

Evidence for the shikimate pathway in apicomplexan parasites

Fiona Roberts;Fiona Roberts;Craig W. Roberts;Jennifer J. Johnson;Dennis E. Kyle.
Nature (1998)

618 Citations

Clinical Studies of Atovaquone, Alone or in Combination with other Antimalarial Drugs, for Treatment of Acute Uncomplicated Malaria in Thailand

S Looareesuwan;C Viravan;H K Webster;D E Kyle.
American Journal of Tropical Medicine and Hygiene (1996)

491 Citations

Amplification of pfmdr1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand

Craig M. Wilson;Sarah K. Volkman;Sodsri Thaithong;Roger K. Martin.
Molecular and Biochemical Parasitology (1993)

357 Citations

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Wesley C. Van Voorhis;John H. Adams;Roberto Adelfio;Roberto Adelfio;Vida Ahyong.
PLOS Pathogens (2016)

351 Citations

A novel multiple-stage antimalarial agent that inhibits protein synthesis

Beatriz Baragaña;Irene Hallyburton;Marcus C. S. Lee;Marcus C. S. Lee;Neil R. Norcross.
Nature (2015)

345 Citations

Cardiac effects of antimalarial treatment with halofantrine

F. Nosten;F. O. Ter Kuile;C. Luxemburger;C. Woodrow.
The Lancet (1993)

337 Citations

Genetic Diversity of Plasmodium falciparum Histidine-Rich Protein 2 (PfHRP2) and Its Effect on the Performance of PfHRP2-Based Rapid Diagnostic Tests

Joanne Baker;James McCarthy;Michelle Gatton;Dennis E. Kyle.
The Journal of Infectious Diseases (2005)

317 Citations

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