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Elizabeth A. Ashley

Elizabeth A. Ashley

University of Oxford
United Kingdom

Overview

What is she best known for?

The fields of study she is best known for:

  • Internal medicine
  • Malaria
  • Gene

Elizabeth A. Ashley focuses on Malaria, Plasmodium falciparum, Artemisinin, Artesunate and Drug resistance. Her Malaria study is related to the wider topic of Immunology. Her Plasmodium falciparum research includes elements of Virology, Selective sweep, Haplotype, Single-nucleotide polymorphism and Pharmacology.

Elizabeth A. Ashley works in the field of Artemisinin, namely Dihydroartemisinin/piperaquine. She has included themes like Artemether, Internal medicine, Piperaquine, Plasmodium vivax and Mefloquine in her Artesunate study. Her studies in Drug resistance integrate themes in fields like Genome, Combination therapy and Genotype.

Her most cited work include:

  • Spread of Artemisinin Resistance in Plasmodium falciparum Malaria (1263 citations)
  • Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study (709 citations)
  • Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study (709 citations)

What are the main themes of her work throughout her whole career to date?

Elizabeth A. Ashley mainly focuses on Malaria, Plasmodium falciparum, Artemisinin, Internal medicine and Artesunate. Her work investigates the relationship between Malaria and topics such as Pharmacology that intersect with problems in Dihydroartemisinin. Her work deals with themes such as Drug resistance and Virology, which intersect with Plasmodium falciparum.

Her Artemisinin study combines topics in areas such as Clearance rate, Multiple drug resistance, Parasite hosting and Combination therapy. Her biological study deals with issues like Surgery, which deal with fields such as Pregnancy. Her Artesunate research is multidisciplinary, relying on both Quinine and Mefloquine.

She most often published in these fields:

  • Malaria (86.85%)
  • Plasmodium falciparum (60.90%)
  • Artemisinin (51.21%)

What were the highlights of her more recent work (between 2018-2021)?

  • Malaria (86.85%)
  • Internal medicine (43.60%)
  • Plasmodium falciparum (60.90%)

In recent papers she was focusing on the following fields of study:

Malaria, Internal medicine, Plasmodium falciparum, Artemisinin and Antibiotic resistance are her primary areas of study. Her Malaria research incorporates elements of Algorithm, Feature and Genetic epidemiology. Her Plasmodium falciparum study incorporates themes from Drug resistance and Virology.

Her work carried out in the field of Drug resistance brings together such families of science as Single-nucleotide polymorphism, Genotype and Medical emergency. Elizabeth A. Ashley has researched Artemisinin in several fields, including Mefloquine, Tolerability, Parasitemia and Parasite hosting. Her biological study spans a wide range of topics, including Global health and Psychological intervention.

Between 2018 and 2021, her most popular works were:

  • Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study. (103 citations)
  • Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study. (103 citations)
  • Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance rates after artemisinin-based treatments : a WWARN individual patient data meta-analysis (93 citations)

In her most recent research, the most cited papers focused on:

  • Internal medicine
  • Malaria
  • Gene

Elizabeth A. Ashley spends much of her time researching Plasmodium falciparum, Malaria, Artemisinin, Internal medicine and Meta-analysis. The Plasmodium falciparum study combines topics in areas such as Drug resistance, Genotype and Virology. Her Malaria research focuses on Plasmodium vivax in particular.

Her studies deal with areas such as Parasitemia and Parasite hosting as well as Artemisinin. Elizabeth A. Ashley interconnects Antimicrobial susceptibility and Mefloquine in the investigation of issues within Internal medicine. Her Piperaquine research is multidisciplinary, incorporating elements of Global health and Dihydroartemisinin/piperaquine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

Ashley Ea;Dhorda M;Fairhurst Rm;Amaratunga C.
The New England Journal of Medicine (2014)

2019 Citations

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study

Aung Pyae Phyo;Standwell Nkhoma;Kasia Stepniewska;Kasia Stepniewska;Elizabeth A. Ashley;Elizabeth A. Ashley.
The Lancet (2012)

989 Citations

Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number.

Ric N. Price;Ric N. Price;Anne Catrin Uhlemann;Alan Brockman;Rose McGready.
The Lancet (2004)

965 Citations

Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: a systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic response using individual patient data

EA Ashley;F Aweeka;KI Barnes;Q Bassat.
BMC Medicine (2015)

647 Citations

Genetic architecture of artemisinin-resistant Plasmodium falciparum.

O Miotto;R Amato;E A Ashley;B MacInnis.
Nature Genetics (2015)

540 Citations

A Major Genome Region Underlying Artemisinin Resistance in Malaria

Ian H. Cheeseman;Becky A. Miller;Shalini Nair;Standwell Nkhoma.
Science (2012)

452 Citations

Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker

Kyaw M. Tun;Mallika Imwong;Khin M Lwin;Aye A. Win.
Lancet Infectious Diseases (2015)

445 Citations

Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

Sachel Mok;Elizabeth A. Ashley;Elizabeth A. Ashley;Pedro E. Ferreira;Lei Zhu.
Science (2015)

410 Citations

Changes in the Treatment Responses to Artesunate-Mefloquine on the Northwestern Border of Thailand during 13 Years of Continuous Deployment

Verena Ilona Carrara;Julien Zwang;Elizabeth A. Ashley;Elizabeth A. Ashley;Ric N. Price;Ric N. Price.
PLOS ONE (2009)

290 Citations

Genomic epidemiology of artemisinin resistant malaria

A. Amato;A. Amato;O. Miotto;O. Miotto;O. Miotto;C.J. Woodrow;C.J. Woodrow;J. Almagro-Garcia;J. Almagro-Garcia.
eLife (2016)

240 Citations

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