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Medicine

D-Index
84
Citations
28470
World Ranking
15006
National Ranking
7585

Overview

Timothy L. Ratliff is affiliated with Purdue University West Lafayette in the United States. Their research primarily spans the fields of medicine, immunology and microbiology, and biochemistry, genetics and molecular biology, with a focus on immunology, molecular biology, surgery, pulmonary and respiratory medicine, and oncology.

The main topics covered in their work include immune cells in cancer, immune cell function and interaction, urinary bladder and prostate research, cancer immunotherapy and biomarkers, immunotherapy and immune responses, bladder and urothelial cancer treatments, and prostate cancer diagnosis and treatment.

Ratliff has published extensively, with notable recent papers including:

  • Naturally-Occurring Invasive Urothelial Carcinoma in Dogs, a Unique Model to Drive Advances in Managing Muscle Invasive Bladder Cancer in Humans, 2020, Frontiers in Oncology
  • TNF is a potential therapeutic target to suppress prostatic inflammation and hyperplasia in autoimmune disease, 2022, Nature Communications
  • Folate Receptor Beta Designates Immunosuppressive Tumor-Associated Myeloid Cells That Can Be Reprogrammed with Folate-Targeted Drugs, 2020, Cancer Research
  • Protein Arginine Methyltransferase 5 Promotes pICln-Dependent Androgen Receptor Transcription in Castration-Resistant Prostate Cancer, 2020, Cancer Research
  • Thrombin-PAR1 signaling in pancreatic cancer promotes an immunosuppressive microenvironment, 2020, Journal of Thrombosis and Haemostasis

Frequent collaborators include Gregory M. Cresswell, Meaghan M. Broman, Nadia A. Lanman, Renee E. Vickman, and Brian T. Helfand.

Ratliff's research is published often in venues such as Cancer Research, Frontiers in Immunology, bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Oncology, and Nature Communications. Their largest number of publications is found in Cancer Research and Frontiers in Immunology.

Best Publications

  • Measurement of prostate-specific antigen in serum as a screening test for prostate cancer.

    William J. Catalona;Deborah S. Smith;Timothy L. Ratliff;Kathy M. Dodds

  • Comparison of digital rectal examination and serum prostate specific antigen in the early detection of prostate cancer: results of a multicenter clinical trial of 6,630 men.

    William J. Catalona;Jerome P. Richie;Frederick R. Ahmann;M'Liss A. Hudson

  • Detection of organ-confined prostate cancer is increased through prostate-specific antigen-based screening.

    William J. Catalona;Deborah S. Smith;Timothy L. Ratliff;Joseph W. Basler

  • Evaluation of percentage of free serum prostate-specific antigen to improve specificity of prostate cancer screening.

    William J. Catalona;Deborah S. Smith;Robert L. Wolfert;Tang J. Wang

  • Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness

    Shuhua Yue;Junjie Li;Seung Young Lee;Hyeon Jeong Lee

  • Effect of Inflammation and Benign Prostatic Hyperplasia on Elevated Serum Prostate Specific Antigen Levels

    Robert B. Nadler;Peter A. Humphrey;Deborah S. Smith;William J. Catalona

  • Platelet-mediated modulation of adaptive immunity. A communication link between innate and adaptive immune compartments.

    Bennett D Elzey;Jun Tian;Robert J Jensen;Axel K Swanson

  • Hepatocyte growth factor and its receptor (c-MET) in prostatic carcinoma.

    Peter A. Humphrey;Xiaopei Zhu;Reza Zarnegar;Paul E. Swanson

  • Selection of Optimal Prostate Specific Antigen Cutoffs for Early Detection of Prostate Cancer: Receiver Operating Characteristic Curves

    W.J. Catalona;M.A. Hudson;P.T. Scardino;J.P. Richie

  • Risks and benefits of repeated courses of intravesical bacillus Calmette-Guerin therapy for superficial bladder cancer

    William J. Catalona;M’liss A. Hudson;Daniel P. Gillen;Gerald L. Andriole

  • T-Cell Subsets Required for Intravesical BCG Immunotherapy for Bladder Cancer

    Timothy L. Ratliff;Julie K. Ritchey;Jerry J.J. Yuan;Gerald L. Andriole

  • Comparison of prostate specific antigen concentration versus prostate specific antigen density in the early detection of prostate cancer: receiver operating characteristic curves.

    William J. Catalona;Jerome P. Richie;Jean B. deKernion;Frederick R. Ahmann

  • Characterization of fibronectin-binding antigens released by Mycobacterium tuberculosis and Mycobacterium bovis BCG.

    C. Abou-Zeid;T. L. Ratliff;H. G. Wiker;M. Harboe

  • Platelet-mediated modulation of adaptive immunity: unique delivery of CD154 signal by platelet-derived membrane vesicles.

    Daniel L. Sprague;Bennett D. Elzey;Scott A. Crist;Thomas J. Waldschmidt

  • Requirement of a Thymus Dependent Immune Response for Bcg-mediated Antitumor Activity

    Timothy L. Ratliff;Daniel Gillen;William J. Catalona

  • Effects of Rectal Examination, Prostatic Massage, Ultrasonography and Needle Biopsy on Serum Prostate Specific Antigen Levels

    Jerry J.J. Yuan;Douglas E. Coplen;John A. Petros;Robert S. Figenshau

  • Effect of patient age on early detection of prostate cancer with serum prostate-specific antigen and digital rectal examination

    Jerome P. Richie;William J. Catalona;Frederick R. Ahmann;M'Liss A. Hudson

  • NK cells are essential for effective BCG immunotherapy

    Sven Brandau;Josef Riemensberger;Marc Jacobsen;Don Kemp

  • TGF-Beta Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia

    Timothy L. Ratliff

  • Urine markers for bladder cancer surveillance: a systematic review.

    Timothy L. Ratliff

Frequent Co-Authors

William J. Catalona
William J. Catalona Northwestern University
Louis R. Kavoussi
Louis R. Kavoussi Northwell Health
Eric J. Brown
Eric J. Brown University of Pennsylvania
Thomas S. Griffith
Thomas S. Griffith University of Minnesota
Ji-Xin Cheng
Ji-Xin Cheng Boston University
Liang Cheng
Liang Cheng Brown University
Jerome P. Richie
Jerome P. Richie Brigham and Women's Hospital
Stephen F. Konieczny
Stephen F. Konieczny Purdue University West Lafayette
Peter T. Scardino
Peter T. Scardino Memorial Sloan Kettering Cancer Center
Shihuan Kuang
Shihuan Kuang Purdue University West Lafayette

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