World's Best Scientists 2026 revealed!
John A. Stamatoyannopoulos

John A. Stamatoyannopoulos

D-Index & Metrics

Genetics

D-Index
105
Citations
92671
World Ranking
613
National Ranking
309

Medicine

D-Index
105
Citations
92937
World Ranking
6632
National Ranking
3514

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genetics

His main research concerns Genetics, Computational biology, Human genome, Chromatin and Genome. His work on Genetics deals in particular with DNase-Seq, DNA methylation, Genomics, ENCODE and Epigenomics. As part of his studies on Computational biology, he often connects relevant areas like Pre-replication complex.

His Human genome research incorporates themes from Human mitochondrial genetics, Human disease, ATAC-seq and Mitochondrion. His research in Chromatin intersects with topics in Enhancer, Transcription factor, Chromatin immunoprecipitation and DNase I hypersensitive site. His Genome research focuses on subjects like Locus, which are linked to Chromatin Loop, Chromatin Fiber, Genomic organization, Chromosome Territory and Chromosome conformation capture.

His most cited work include:

  • Comprehensive mapping of long-range interactions reveals folding principles of the human genome. (4920 citations)
  • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project (4297 citations)
  • Integrative analysis of 111 reference human epigenomes (3776 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Genetics, Computational biology, Chromatin, Genome and Human genome. His research in Transcription factor, Gene, Enhancer, Regulatory sequence and Genomics are components of Genetics. The various areas that John A. Stamatoyannopoulos examines in his Computational biology study include Phenotype, ENCODE, DNA, Promoter and Regulation of gene expression.

His work deals with themes such as Epigenomics, DNA methylation and Cell biology, which intersect with Chromatin. As a part of the same scientific family, he mostly works in the field of Genome, focusing on Chromosome conformation capture and, on occasion, DNA Replication Timing. His study looks at the relationship between Human genome and topics such as DNase-Seq, which overlap with DNase I hypersensitive site.

He most often published in these fields:

  • Genetics (57.47%)
  • Computational biology (40.27%)
  • Chromatin (40.27%)

What were the highlights of his more recent work (between 2017-2021)?

  • Computational biology (40.27%)
  • Chromatin (40.27%)
  • Gene (23.98%)

In recent papers he was focusing on the following fields of study:

John A. Stamatoyannopoulos mostly deals with Computational biology, Chromatin, Gene, Genome and Transcription factor. His biological study spans a wide range of topics, including Human genome, Epigenomics, Allele, Genome editing and Regulation of gene expression. John A. Stamatoyannopoulos works mostly in the field of Human genome, limiting it down to topics relating to Regulatory sequence and, in certain cases, Human genetic variation.

The concepts of his Chromatin study are interwoven with issues in Proteome, Haematopoiesis, Promoter, Nuclear protein and Bromodomain. His Genome research incorporates elements of DNA, Effector, Cell biology, Chromosome conformation capture and Transcription. Tissue-Specific Gene Expression is a subfield of Genetics that John A. Stamatoyannopoulos tackles.

Between 2017 and 2021, his most popular works were:

  • Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics. (320 citations)
  • The GTEx Consortium atlas of genetic regulatory effects across human tissues (238 citations)
  • Expanded encyclopaedias of DNA elements in the human and mouse genomes (141 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genome

John A. Stamatoyannopoulos focuses on Computational biology, Gene, Genome, Chromatin and Regulation of gene expression. His Computational biology study integrates concerns from other disciplines, such as Disjunctive normal form, Human genetics and Functional genomics, Genomics. His research in Genome is mostly focused on Human genome.

John A. Stamatoyannopoulos usually deals with Human genome and limits it to topics linked to Regulatory sequence and Human genetic variation and Promoter. His work focuses on many connections between Chromatin and other disciplines, such as Epigenomics, that overlap with his field of interest in ENCODE. His Genetic variation study results in a more complete grasp of Genetics.

Best Publications

  • Comprehensive mapping of long-range interactions reveals folding principles of the human genome.

    Erez Lieberman-Aiden;Nynke L. van Berkum;Louise Williams;Maxim Imakaev

  • Integrative analysis of 111 reference human epigenomes

    Anshul Kundaje;Wouter Meuleman;Wouter Meuleman;Jason Ernst

  • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

    Ewan Birney;John A. Stamatoyannopoulos;Anindya Dutta;Roderic Guigó

  • The GTEx Consortium atlas of genetic regulatory effects across human tissues

    F Aguet;AN Barbeira;R Bonazzola;A Brown

  • Systematic localization of common disease-associated variation in regulatory DNA.

    Matthew T. Maurano;Richard Humbert;Eric Rynes;Robert E. Thurman

  • The ENCODE (ENCyclopedia of DNA elements) Project

    E. A. Feingold;P. J. Good;M. S. Guyer;S. Kamholz

  • The accessible chromatin landscape of the human genome

    Robert E. Thurman;Eric Rynes;Richard Humbert;Jeff Vierstra

  • An integrated encyclopedia of DNA elements in the human genome

    Ian Dunham;Anshul Kundaje;Shelley F. Aldred;Patrick J. Collins

  • Expanded encyclopaedias of DNA elements in the human and mouse genomes

    Jill E. Moore;Michael J. Purcaro;Henry E. Pratt;Charles B. Epstein

  • ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

    Stephen G. Landt;Georgi K. Marinov;Anshul Kundaje;Pouya Kheradpour

  • Quantifying similarity between motifs

    Shobhit Gupta;John A Stamatoyannopoulos;Timothy L Bailey;William Stafford Noble

  • A comparative encyclopedia of DNA elements in the mouse genome

    Feng Yue;Feng Yue;Yong Cheng;Alessandra Breschi;Jeff Vierstra

  • The NIH Roadmap Epigenomics Mapping Consortium

    Bradley E Bernstein;John A Stamatoyannopoulos;Joseph F Costello;Bing Ren

  • A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

    Richard M. Myers;John Stamatoyannopoulos;Michael Snyder;Ian Dunham

  • Guidelines for investigating causality of sequence variants in human disease

    D G MacArthur;T A Manolio;D P Dimmock;H L Rehm

  • Mapping and sequencing of structural variation from eight human genomes

    Jeffrey M. Kidd;Gregory M. Cooper;William F. Donahue;Hillary S. Hayden

  • Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics.

    Alvaro N. Barbeira;Scott P. Dickinson;Rodrigo Bonazzola;Jiamao Zheng

  • Chromatin accessibility pre-determines glucocorticoid receptor binding patterns

    Sam John;Peter J. Sabo;Robert E. Thurman;Myong Hee Sung

  • Comprehensive analysis of the chromatin landscape in Drosophila melanogaster

    Peter V. Kharchenko;Artyom A. Alekseyenko;Artyom A. Alekseyenko;Yuri B. Schwartz;Aki Minoda

  • BEDOPS: high-performance genomic feature operations.

    Shane J. Neph;Scott Kuehn;Alex P. Reynolds;Eric Haugen

Frequent Co-Authors

Richard Sandstrom
Richard Sandstrom University of Washington
Michael Snyder
Michael Snyder Stanford University
William Stafford Noble
William Stafford Noble University of Washington
Shamil R. Sunyaev
Shamil R. Sunyaev Harvard University
Roderic Guigó
Roderic Guigó Pompeu Fabra University
Job Dekker
Job Dekker University of Massachusetts Chan Medical School
Mark Groudine
Mark Groudine Fred Hutchinson Cancer Research Center
Rajinder Kaul
Rajinder Kaul University of Washington
Michael O. Dorschner
Michael O. Dorschner University of Washington

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