World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
104
Citations
89973
World Ranking
635
National Ranking
321

Molecular Biology

D-Index
104
Citations
89973
World Ranking
454
National Ranking
255

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Job Dekker is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research predominantly focuses on biochemistry, genetics, and molecular biology, with particular emphasis on molecular biology as reflected by the majority of their publications.

The scientist's main areas of study include genomics and chromatin dynamics, RNA research and splicing, chromosomal and genetic variations, RNA and protein synthesis mechanisms, DNA repair mechanisms, epigenetics and DNA methylation, and RNA modifications related to cancer. These topics indicate a broad engagement with understanding genetic material organization, functional genomic processes, and cellular molecular mechanisms.

Regarding recent scientific contributions, Job Dekker has authored several papers in well-known journals, including:

  • Ultrastructural Details of Mammalian Chromosome Architecture, 2020, Molecular Cell
  • Mechanisms and Functions of Chromosome Compartmentalization, 2020, Trends in Biochemical Sciences
  • Systematic evaluation of chromosome conformation capture assays, 2021, Nature Methods
  • Perspectives on ENCODE, 2020, Nature
  • SPEN integrates transcriptional and epigenetic control of X-inactivation, 2020, Nature

Frequent co-authors collaborating with Dekker include Johan H. Gibcus, Sergey V. Venev, Liyan Yang, Leonid A. Mirny, and Ye Zhan. These ongoing collaborations reflect a network of researchers working on interconnected areas of chromosome biology, genomics, and molecular interactions.

The scientist has published extensively in several prominent venues. The primary outlets featuring their work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Nature Structural & Molecular Biology
  • Molecular Cell
  • Nature Genetics

Job Dekker's publication record includes 183 papers classified under biochemistry, genetics, and molecular biology. Subfields represented in their research more specifically include molecular biology, plant science, genetics, cell biology, and ecology, which shows a varied but focused research portfolio crossing multiple biological disciplines.

Best Publications

  • Comprehensive mapping of long-range interactions reveals folding principles of the human genome.

    Erez Lieberman-Aiden;Nynke L. van Berkum;Louise Williams;Maxim Imakaev

  • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

    Ewan Birney;John A. Stamatoyannopoulos;Anindya Dutta;Roderic Guigó

  • Capturing Chromosome Conformation

    Job Dekker;Karsten Rippe;Martijn Dekker;Nancy Kleckner

  • Spatial partitioning of the regulatory landscape of the X-inactivation centre

    Elphège P. Nora;Bryan R. Lajoie;Edda G. Schulz;Luca Giorgetti;Luca Giorgetti;Luca Giorgetti

  • The ENCODE (ENCyclopedia of DNA elements) Project

    E. A. Feingold;P. J. Good;M. S. Guyer;S. Kamholz

  • The accessible chromatin landscape of the human genome

    Robert E. Thurman;Eric Rynes;Richard Humbert;Jeff Vierstra

  • An integrated encyclopedia of DNA elements in the human genome

    Ian Dunham;Anshul Kundaje;Shelley F. Aldred;Patrick J. Collins

  • HiC-Pro: an optimized and flexible pipeline for Hi-C data processing

    Nicolas Servant;Nelle Varoquaux;Nelle Varoquaux;Nelle Varoquaux;Bryan R. Lajoie;Eric Viara

  • Expanded encyclopaedias of DNA elements in the human and mouse genomes

    Jill E. Moore;Michael J. Purcaro;Henry E. Pratt;Charles B. Epstein

  • Mediator and cohesin connect gene expression and chromatin architecture

    Michael H. Kagey;Jamie Jennifer Newman;Steve Bilodeau;Ye Zhan

  • A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

    Kevin C. Wang;Yul W. Yang;Bo Liu;Amartya Sanyal

  • The long-range interaction landscape of gene promoters

    Amartya Sanyal;Bryan R. Lajoie;Gaurav Jain;Job Dekker

  • Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization.

    Elphège P. Nora;Anton Goloborodko;Anne-Laure Valton;Johan H. Gibcus

  • A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

    Richard M. Myers;John Stamatoyannopoulos;Michael Snyder;Ian Dunham

  • Iterative correction of Hi-C data reveals hallmarks of chromosome organization

    Maxim Imakaev;Geoffrey Fudenberg;Rachel Patton McCord;Natalia Naumova

  • Chromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elements

    Josée Dostie;Todd A. Richmond;Ramy A. Arnaout;Rebecca R. Selzer

  • Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment

    Jennifer E. Phillips-Cremins;Michael E G Sauria;Amartya Sanyal;Tatiana I. Gerasimova

  • Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data

    Job Dekker;Marc A. Marti-Renom;Leonid A. Mirny

  • Hi-C: a comprehensive technique to capture the conformation of genomes

    Jon-Matthew Belton;Rachel Patton McCord;Johan Harmen Gibcus;Natalia Naumova

  • Activation of proto-oncogenes by disruption of chromosome neighborhoods

    Denes Hnisz;Abraham S. Weintraub;Daniel S. Day;Anne-Laure Valton

Frequent Co-Authors

Bryan R. Lajoie
Bryan R. Lajoie University of Massachusetts Chan Medical School
John A. Stamatoyannopoulos
John A. Stamatoyannopoulos University of Washington
Edith Heard
Edith Heard Collège de France
Zhiping Weng
Zhiping Weng University of Massachusetts Chan Medical School
William Stafford Noble
William Stafford Noble University of Washington
Ross C. Hardison
Ross C. Hardison Pennsylvania State University
Mark Gerstein
Mark Gerstein Yale University
Thomas R. Gingeras
Thomas R. Gingeras Cold Spring Harbor Laboratory
Anshul Kundaje
Anshul Kundaje Stanford University

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