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D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
48885
World Ranking
7601
National Ranking
3456

Overview

David A. Gewirtz is affiliated with Virginia Commonwealth University in the United States. Their research spans multiple fields, primarily focusing on medicine as well as biochemistry, genetics, and molecular biology. Within these broad areas, their work concentrates on molecular biology, physiology, oncology, epidemiology, and pharmacology.

Their research covers a range of topics, including:

  • Telomeres, Telomerase, and Senescence
  • Autophagy in Disease and Therapy
  • Cannabis and Cannabinoid Research
  • Protein Degradation and Inhibitors
  • Histone Deacetylase Inhibitors Research
  • Ubiquitin and Proteasome Pathways
  • Chemotherapy-Induced Organ Toxicity Mitigation

Gewirtz has contributed to scientific literature published in a variety of journals. Some of the frequent publication venues include:

  • Cancers
  • International Journal of Molecular Sciences
  • Advances in Cancer Research
  • Molecular Pharmacology
  • Journal of Pharmacology and Experimental Therapeutics

Their notable recent papers include:

  • "Autophagy in major human diseases," 2021, The EMBO Journal
  • "Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy," 2021, JNCI Journal of the National Cancer Institute
  • "Therapy-Induced Senescence: An "Old" Friend Becomes the Enemy," 2020, Cancers
  • "The lysosome as an imperative regulator of autophagy and cell death," 2021, Cellular and Molecular Life Sciences
  • "Clearance of therapy-induced senescent tumor cells by the senolytic ABT-263 via interference with BCL-XL-BAX interaction," 2020, Molecular Oncology

The scientist often collaborates with a core group of coauthors. Frequent co-authors include:

  • Tareq Saleh
  • Ahmed M. Elshazly
  • Valerie J. Carpenter
  • Hisashi Harada
  • Nipa Patel

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Molecular definitions of autophagy and related processes

    Lorenzo Galluzzi;Lorenzo Galluzzi;Eric H. Baehrecke;Andrea Ballabio;Patricia Boya

  • Autophagy in major human diseases

    Daniel J. Klionsky;Giulia Petroni;Ravi K. Amaravadi;Eric H. Baehrecke

  • Autophagy in malignant transformation and cancer progression

    Lorenzo Galluzzi;Federico Pietrocola;Federico Pietrocola;José Manuel Bravo-San Pedro;José Manuel Bravo-San Pedro;Ravi K. Amaravadi

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway.

    W D Jarvis;R N Kolesnick;F A Fornari;R S Traylor

  • Interference by doxorubicin with DNA unwinding in MCF-7 breast tumor cells

    F A Fornari;J K Randolph;J C Yalowich;M K Ritke

  • The Four Faces of Autophagy: Implications for Cancer Therapy

    David A. Gewirtz

  • A comprehensive glossary of autophagy-related molecules and processes (2nd edition)

    Daniel J Klionsky;Eric H. Baehrecke;John H. Brumell;Charleen T. Chu

  • Accelerated senescence: An emerging role in tumor cell response to chemotherapy and radiation

    David A. Gewirtz;Shawn E. Holt;Lynne W. Elmore

  • Adriamycin-induced Senescence in Breast Tumor Cells Involves Functional p53 and Telomere Dysfunction *

    Lynne W. Elmore;Catherine W. Rehder;Xu Di;Patricia A. McChesney

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • A comprehensive glossary of autophagy-related molecules and processes.

    Daniel J. Klionsky;Patrice Codogno;Ana Maria Cuervo;Vojo Deretic

  • Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells.

    W D Jarvis;F A Fornari;J L Browning;D A Gewirtz

  • Therapy-induced senescence: opportunities to improve anti-cancer therapy

    Pataje G Prasanna;Deborah E Citrin;Jeffrey Hildesheim;Mansoor M Ahmed

  • Therapy-Induced Senescence: An "Old" Friend Becomes the Enemy.

    Tareq Saleh;Sarah Bloukh;Valerie J. Carpenter;Enas Alwohoush

  • Autophagy and senescence: a partnership in search of definition.

    David A. Gewirtz

Frequent Co-Authors

Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Antonio Abbate
Antonio Abbate University of Virginia
David C. Rubinsztein
David C. Rubinsztein University of Cambridge
Guido Kroemer
Guido Kroemer Université Paris Cité
Sergio Lavandero
Sergio Lavandero University of Chile
Jayanta Debnath
Jayanta Debnath University of California, San Francisco
Sharon A. Tooze
Sharon A. Tooze The Francis Crick Institute
Francesco Cecconi
Francesco Cecconi Catholic University of the Sacred Heart
Vojo Deretic
Vojo Deretic University of New Mexico
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine

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