World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
61371
World Ranking
6094
National Ranking
2865

Overview

Jayanta Debnath is affiliated with the University of California, San Francisco in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with extensive contributions to medicine. Within these broader fields, the main subfields addressed in their work include molecular biology, epidemiology, neurology, cell biology, and immunology.

The scientist's research topics cover several areas related to cellular and molecular mechanisms, prominently featuring autophagy in disease and therapy. Other significant topics include extracellular vesicles in disease, epigenetics and DNA methylation, endoplasmic reticulum stress and disease, RNA modifications and cancer, Parkinson's disease mechanisms and treatments, and Toxoplasma gondii research studies.

Jayanta Debnath has published numerous scholarly articles, frequently in journals such as Autophagy, Nature, Nature Cell Biology, Nature Reviews Molecular Cell Biology, and Cell. Some of the recent papers authored or coauthored by them are:

  • Autophagy and autophagy-related pathways in cancer, 2023, Nature Reviews Molecular Cell Biology
  • Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I, 2020, Nature
  • The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles, 2020, Nature Cell Biology
  • Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency, 2020, Nature
  • Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules, 2021, Cell

Their frequent coauthors include Andrew M. Leidal, Timothy Marsh, Tan Nguyen, Eric J. Huang, and Arun P. Wiita. Among these collaborators, Andrew M. Leidal has been involved in 14 joint publications, highlighting a significant partnership.

Jayanta Debnath's contributions span multiple high-impact journals with the largest number of publications appearing in Autophagy, followed by Nature and Nature Cell Biology. The diversity of publication venues reflects a broad engagement with cellular mechanisms and molecular pathways related to autophagy and disease processes.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

    Jayanta Debnath;Senthil K. Muthuswamy;Senthil K. Muthuswamy;Joan S. Brugge

  • Molecular definitions of autophagy and related processes

    Lorenzo Galluzzi;Lorenzo Galluzzi;Eric H. Baehrecke;Andrea Ballabio;Patricia Boya

  • Autophagy in malignant transformation and cancer progression

    Lorenzo Galluzzi;Federico Pietrocola;Federico Pietrocola;José Manuel Bravo-San Pedro;José Manuel Bravo-San Pedro;Ravi K. Amaravadi

  • Modelling glandular epithelial cancers in three-dimensional cultures.

    Jayanta Debnath;Joan S. Brugge

  • Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

    Patricia Spilman;Natalia Podlutskaya;Matthew J. Hart;Jayanta Debnath

  • Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

    Keisuke Yamamoto;Anthony Venida;Julian Yano;Douglas E. Biancur

  • Autophagy at the crossroads of catabolism and anabolism

    Jasvinder Kaur;Jayanta Debnath

  • The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.

    Jayanta Debnath;Kenna R. Mills;Nicole L. Collins;Mauricio J. Reginato

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Targeting Autophagy in Cancer: Recent Advances and Future Directions

    Ravi K. Amaravadi;Alec C. Kimmelman;Jayanta Debnath

  • Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis.

    Mauricio J. Reginato;Kenna R. Mills;Jessica K. Paulus;Danielle K. Lynch

  • Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival

    Christopher Fung;Rebecca Lock;Sizhen Gao;Eduardo Salas

  • FOXO3A directs a protective autophagy program in haematopoietic stem cells

    Matthew R. Warr;Mikhail Binnewies;Johanna Flach;Damien Reynaud

  • Does autophagy contribute to cell death

    Jayanta Debnath;Eric H. Baehrecke;Guido Kroemer

  • Autophagy as a Stress-Response and Quality-Control Mechanism: Implications for Cell Injury and Human Disease

    Lyndsay Murrow;Jayanta Debnath

  • Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation

    Rebecca Lock;Srirupa Roy;Candia M. Kenific;Judy S. Su

Frequent Co-Authors

Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Eric H. Baehrecke
Eric H. Baehrecke University of Massachusetts Chan Medical School
Guido Kroemer
Guido Kroemer Université Paris Cité
Fulvio Reggiori
Fulvio Reggiori University of Groningen
Sergio Lavandero
Sergio Lavandero University of Chile
Alec C. Kimmelman
Alec C. Kimmelman New York University
David A. Gewirtz
David A. Gewirtz Virginia Commonwealth University
Kevin M. Ryan
Kevin M. Ryan University of Glasgow
Joan S. Brugge
Joan S. Brugge Harvard University
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine

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