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Noboru Mizushima

Noboru Mizushima

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
152
Citations
191189
World Ranking
164
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2022 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Noboru Mizushima is affiliated with the University of Tokyo in Japan. Their research primarily focuses on the intersection of biochemistry, genetics, and molecular biology, with significant contributions also in medical studies. Their scientific work is notably concentrated in the subfields of epidemiology, molecular biology, cell biology, parasitology, and physiology.

The core topics addressed in their research include autophagy in disease and therapy, cellular transport and secretion, endoplasmic reticulum stress and disease, Toxoplasma gondii research studies, calcium signaling and nucleotide metabolism, ubiquitin and proteasome pathways, as well as mosquito-borne diseases and control.

Mizushima's frequent publication venues highlight a strong presence in both specialized and broad-scope journals. These include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Autophagy
  • eLife
  • The EMBO Journal
  • Nature

They have several recent scholarly articles which provide insights into their areas of expertise and research focus. Notable recent publications include:

  • Autophagy in Human Diseases, 2020, New England Journal of Medicine
  • Autophagy in major human diseases, 2021, The EMBO Journal
  • Lysosome biology in autophagy, 2020, Cell Discovery
  • Autophagy genes in biology and disease, 2023, Nature Reviews Genetics
  • Structure, lipid scrambling activity and role in autophagosome formation of ATG9A, 2020, Nature Structural & Molecular Biology

Mizushima has collaborated extensively with other researchers, contributing to a network of frequent co-authors. These collaborators include:

  • Hayashi Yamamoto
  • Ikuko Koyama-Honda
  • Chieko Saito
  • Haruka Chino
  • Jun-Ichi Sakamaki

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

    Yukiko Kabeya;Noboru Mizushima;Noboru Mizushima;Takashi Ueno;Akitsugu Yamamoto

  • Autophagy fights disease through cellular self-digestion

    Noboru Mizushima;Beth Levine;Ana Maria Cuervo;Daniel J. Klionsky

  • Autophagy: Renovation of Cells and Tissues

    Noboru Mizushima;Masaaki Komatsu

  • Methods in Mammalian Autophagy Research

    Noboru Mizushima;Tamotsu Yoshimori;Beth Levine

  • Autophagy: process and function

    Noboru Mizushima

  • Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

    Taichi Hara;Kenji Nakamura;Makoto Matsui;Makoto Matsui;Makoto Matsui;Akitsugu Yamamoto

  • Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy.

    Sophie Pattingre;Sophie Pattingre;Amina Tassa;Xueping Qu;Xueping Qu;Rita Garuti

  • Autophagy in immunity and inflammation

    Beth Levine;Noboru Mizushima;Herbert W. Virgin

  • Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

    Alexei Degterev;Zhihong Huang;Michael Boyce;Yaqiao Li

  • The role of autophagy during the early neonatal starvation period

    Akiko Kuma;Masahiko Hatano;Makoto Matsui;Makoto Matsui;Akitsugu Yamamoto

  • The Role of Atg Proteins in Autophagosome Formation

    Noboru Mizushima;Tamotsu Yoshimori;Yoshinori Ohsumi

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • How to Interpret LC3 Immunoblotting

    Noboru Mizushima;Tamotsu Yoshimori

  • In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker

    Noboru Mizushima;Akitsugu Yamamoto;Makoto Matsui;Makoto Matsui;Tamotsu Yoshimori

  • Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

    Xueping Qu;Jie Yu;Govind Bhagat;Norihiko Furuya

  • Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

    Masaaki Komatsu;Satoshi Waguri;Takashi Ueno;Junichi Iwata

  • Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

    Nao Hosokawa;Taichi Hara;Takeshi Kaizuka;Chieko Kishi

Frequent Co-Authors

Yoshinori Ohsumi
Yoshinori Ohsumi Tokyo Institute of Technology
Tamotsu Yoshimori
Tamotsu Yoshimori Osaka University
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Masaaki Komatsu
Masaaki Komatsu Juntendo University
Takeshi Noda
Takeshi Noda Osaka University
Akitsugu Yamamoto
Akitsugu Yamamoto Nagahama Institute of Bio-Science and Technology
Daniel J. Klionsky
Daniel J. Klionsky University of Michigan–Ann Arbor
Yasuo Uchiyama
Yasuo Uchiyama Juntendo University
Vojo Deretic
Vojo Deretic University of New Mexico
Eiki Kominami
Eiki Kominami Juntendo University

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