D-Index & Metrics Best Publications
Research.com 2022 Best Female Scientist Award Badge

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Best female scientists D-index 133 Citations 116,131 382 World Ranking 187 National Ranking 122
Biology and Biochemistry D-index 133 Citations 117,236 357 World Ranking 247 National Ranking 176

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Female Scientist Award

2017 - Member of the National Academy of Sciences

2009 - Fellow of the American Association for the Advancement of Science (AAAS)

2007 - Fellow of the American Academy of Arts and Sciences

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • Apoptosis

The scientist’s investigation covers issues in Cell biology, Programmed cell death, Apoptosis, Caspase and Molecular biology. Her Cell biology research is multidisciplinary, incorporating elements of Autophagy and Necroptosis. Her study on Caspase 1 is often connected to Mechanism as part of broader study in Programmed cell death.

Her study focuses on the intersection of Apoptosis and fields such as Necrosis with connections in the field of Signal transducing adaptor protein, Cellular mechanism and Biological evolution. The various areas that Junying Yuan examines in her Caspase study include Proteases, Messenger RNA, Immunology and Intracellular. Junying Yuan combines subjects such as Homologous chromosome, Caspase 12, Oncogene, Mutant and Caspase 8 with her study of Molecular biology.

Her most cited work include:

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4475 citations)
  • Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis (4014 citations)
  • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. (2946 citations)

What are the main themes of her work throughout her whole career to date?

Her primary scientific interests are in Cell biology, Programmed cell death, Apoptosis, Necroptosis and Caspase. Her Cell biology research includes elements of Autophagy and Ubiquitin, Gene. Her research integrates issues of Cell, Cancer research, Immunology, Necrosis and Neuroscience in her study of Programmed cell death.

Her Apoptosis research is multidisciplinary, incorporating perspectives in Molecular biology and Endoplasmic reticulum. The concepts of her Necroptosis study are interwoven with issues in Tumor necrosis factor alpha, Structure–activity relationship, Stereochemistry and Kinase activity. The Caspase study combines topics in areas such as Caspase 3 and Proteases.

She most often published in these fields:

  • Cell biology (64.82%)
  • Programmed cell death (44.47%)
  • Apoptosis (33.67%)

What were the highlights of her more recent work (between 2014-2021)?

  • Cell biology (64.82%)
  • Necroptosis (28.39%)
  • RIPK1 (18.59%)

In recent papers she was focusing on the following fields of study:

Junying Yuan spends much of her time researching Cell biology, Necroptosis, RIPK1, Programmed cell death and Autophagy. Her Cell biology research integrates issues from Ubiquitin and FADD. Necroptosis is a subfield of Apoptosis that Junying Yuan tackles.

Her research in RIPK1 intersects with topics in Tumor necrosis factor alpha, Kinase activity, HEK 293 cells, Neuroinflammation and Proinflammatory cytokine. Her research in Programmed cell death is mostly focused on Intrinsic apoptosis. Her study on Autophagy also encompasses disciplines like

  • Fms-Like Tyrosine Kinase 3 most often made with reference to Cancer cell,
  • Computational biology which intersects with area such as Cell and Autolysosome.

Between 2014 and 2021, her most popular works were:

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4475 citations)
  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1747 citations)
  • Molecular definitions of autophagy and related processes (743 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Apoptosis

Junying Yuan mainly investigates Cell biology, RIPK1, Programmed cell death, Necroptosis and Autophagy. Her research on Cell biology often connects related areas such as Genetically modified mouse. Her studies deal with areas such as Signal transduction and Neuroscience as well as Programmed cell death.

Her Necroptosis study is concerned with Apoptosis in general. In her research on the topic of Apoptosis, Alzheimer's disease is strongly related with Protein kinase A. Her Autophagy study integrates concerns from other disciplines, such as Computational biology and Intracellular.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif.
Autophagy (2021)

8964 Citations

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Autophagy (2016)

7788 Citations

Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

Honglin Li;Hong Zhu;Chi Jie Xu;Junying Yuan.
Cell (1998)

5734 Citations

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta.

Toshiyuki Nakagawa;Hong Zhu;Nobuhiro Morishima;En Li.
Nature (2000)

4182 Citations

Human ICE/CED-3 Protease Nomenclature

Emad S Alnemri;David J Livingston;Donald W Nicholson;Guy Salvesen.
Cell (1996)

3369 Citations

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme

Junying Yuan;Junying Yuan;Shai Shaham;Stephane Ledoux;Hilary M. Ellis.
Cell (1993)

3340 Citations

Mechanisms and Functions of Cell Death

Ellis Re;Yuan Jy;Horvitz Hr.
Annual Review of Cell Biology (1991)

2856 Citations

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

Galluzzi L;Vitale I;Vitale I;Vitale I;Abrams Jm;Alnemri Es.
Cell Death & Differentiation (2012)

2840 Citations

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

Alexei Degterev;Zhihong Huang;Michael Boyce;Yaqiao Li.
Nature Chemical Biology (2005)

2739 Citations

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

Gilad Twig;Alvaro Elorza;Anthony J A Molina;Anthony J A Molina;Hibo Mohamed.
The EMBO Journal (2008)

2627 Citations

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