World's Best Scientists 2026 revealed!
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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
139
Citations
134139
World Ranking
242
National Ranking
154

Biology and Biochemistry

D-Index
141
Citations
140428
World Ranking
252
National Ranking
169

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2017 - Member of the National Academy of Sciences
  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2007 - Fellow of the American Academy of Arts and Sciences

Overview

Junying Yuan is affiliated with Harvard University in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work primarily focuses on molecular biology, immunology, cancer research, epidemiology, and physiology. The main topics of their research include cell death mechanisms and regulation, interferon and immune responses, autophagy in disease and therapy, NF-κB signaling pathways, ubiquitin and proteasome pathways, endoplasmic reticulum stress and disease, and Alzheimer's disease research and treatments.

Their publication record includes numerous articles in prominent scientific venues. Frequent publication outlets for their research comprise Proceedings of the National Academy of Sciences, Nature Communications, Nature Cell Biology, Cell Research, and Molecular Cell.

Junying Yuan has coauthored papers with multiple researchers, including Bing Shan, Daichao Xu, Ying Li, Chengyu Zou, and Lauren Mifflin. The collaboration counts range from seven to seventeen publications per coauthor.

Selected recent papers include:

  • A guide to cell death pathways, 2023, Nature Reviews Molecular Cell Biology
  • Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target, 2020, Nature Reviews Drug Discovery
  • Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke, 2020, Proceedings of the National Academy of Sciences
  • Modulating TRADD to restore cellular homeostasis and inhibit apoptosis, 2020, Nature
  • Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1, 2023, Science

The researcher has been recognized with several honors including membership in the National Academy of Sciences since 2017, fellowship of the American Association for the Advancement of Science (AAAS) since 2009, and fellowship of the American Academy of Arts and Sciences since 2007.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

    Honglin Li;Hong Zhu;Chi Jie Xu;Junying Yuan

  • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta.

    Toshiyuki Nakagawa;Hong Zhu;Nobuhiro Morishima;En Li

  • Classification of cell death: recommendations of the Nomenclature Committee on Cell Death

    G. Kroemer;G. Kroemer;G. Kroemer;L. Galluzzi;L. Galluzzi;L. Galluzzi;P. Vandenabeele;J. Abrams

  • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme

    Junying Yuan;Shai Shaham;S. Ledoux;H. M. Ellis

  • Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

    Gilad Twig;Alvaro Elorza;Anthony J A Molina;Anthony J A Molina;Hibo Mohamed

  • Human ICE/CED-3 Protease Nomenclature

    Emad S Alnemri;David J Livingston;Donald W Nicholson;Guy Salvesen

  • Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

    Alexei Degterev;Zhihong Huang;Michael Boyce;Yaqiao Li

  • Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

    Galluzzi L;Vitale I;Vitale I;Vitale I;Abrams Jm;Alnemri Es

  • Mechanisms and Functions of Cell Death

    R E Ellis;J Y Yuan;H R Horvitz

  • Apoptosis in the nervous system

    Junying Yuan;Bruce A. Yankner

  • Identification of RIP1 kinase as a specific cellular target of necrostatins.

    Alexei Degterev;Junichi Hitomi;Megan Germscheid;Irene L Ch'en

  • Autophagy in cell death: an innocent convict?

    Beth Levine;Junying Yuan

  • Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

    Masayuki Miura;Hong Zhu;Rocco J. Rotello;Erika A. Hartwieg

  • Proteases to die for

    Vincent Cryns;Junying Yuan

  • A Selective Inhibitor of eIF2α Dephosphorylation Protects Cells from ER Stress

    Michael Boyce;Kevin F. Bryant;Céline Jousse;Kai Long

  • A decade of caspases

    Alexei Degterev;Michael Boyce;Junying Yuan

  • Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis.

    Toshiyuki Nakagawa;Junying Yuan

Frequent Co-Authors

Hong Zhu
Hong Zhu Zhejiang University
Dawei Ma
Dawei Ma Chinese Academy of Sciences
Guido Kroemer
Guido Kroemer Université Paris Cité
Oliver Kepp
Oliver Kepp Institut Gustave Roussy
Michael A. Moskowitz
Michael A. Moskowitz Harvard University
Lorenzo Galluzzi
Lorenzo Galluzzi Cornell University
Gregory D. Cuny
Gregory D. Cuny University of Houston
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Gerhard Wagner
Gerhard Wagner Harvard University
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute

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