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D-Index & Metrics

Biology and Biochemistry

D-Index
122
Citations
101899
World Ranking
568
National Ranking
360

Research.com Recognitions

  • 2018 - Fellow, National Academy of Inventors

Overview

Emad S. Alnemri is affiliated with Thomas Jefferson University in the United States and conducts research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several key subfields, including Molecular Biology, Immunology, Pathology and Forensic Medicine, Epidemiology, and Parasitology.

The main topics addressed in their research include:

  • Inflammasome and immune disorders
  • Cell death mechanisms and regulation
  • Phagocytosis and Immune Regulation
  • Chemotherapy-induced organ toxicity mitigation
  • Ion Transport and Channel Regulation
  • Heme Oxygenase-1 and Carbon Monoxide
  • Interferon and immune responses

Alnemri has contributed to scientific literature through various papers published in multiple venues. Notable recent publications include:

  • "Apoptotic cell death in disease-Current understanding of the NCCD 2023," 2023, Cell Death and Differentiation
  • "Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis," 2021, Nature Communications
  • "Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)," 2021, Americanae (AECID Library)
  • "Raptinal Induces Gasdermin E-Dependent Pyroptosis in Naïve and Therapy-Resistant Melanoma," 2022, Molecular Cancer Research
  • "Multiple Autonomous Cell Death Suppression Strategies Ensure Cytomegalovirus Fitness," 2021, Viruses

Frequent publication venues where Alnemri's work appears include:

  • Molecular Cancer Research
  • Cell Death and Differentiation
  • Nature Communications
  • Americanae (AECID Library)
  • Viruses

The scientist collaborates regularly with several researchers, including:

  • Patrizia Agostinis
  • Ivano Amelio
  • Eli Arama
  • Eric H. Baehrecke
  • Douglas R. Green

Emad S. Alnemri received recognition as a Fellow of the National Academy of Inventors in 2018.

Best Publications

  • Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

    Peng Li;Deepak Nijhawan;Imawati Budihardjo;Srinivasa M Srinivasula

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Classification of cell death: recommendations of the Nomenclature Committee on Cell Death

    G. Kroemer;G. Kroemer;G. Kroemer;L. Galluzzi;L. Galluzzi;L. Galluzzi;P. Vandenabeele;J. Abrams

  • Human ICE/CED-3 Protease Nomenclature

    Emad S Alnemri;David J Livingston;Donald W Nicholson;Guy Salvesen

  • Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.

    Franz G. Bauernfeind;Gabor Horvath;Andrea Stutz;Emad S. Alnemri

  • Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

    Galluzzi L;Vitale I;Vitale I;Vitale I;Abrams Jm;Alnemri Es

  • Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner.

    Elizabeth A. Slee;Mary T. Harte;Ruth M. Kluck;Beni B. Wolf

  • The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease

    Yun-Hee Youm;Kim Y. Nguyen;Ryan W Grant;Emily L Goldberg

  • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

    Teresa Fernandes-Alnemri;Je-Wook Yu;Pinaki Datta;Jianghong Wu

  • IAPs block apoptotic events induced by caspase‐8 and cytochrome c by direct inhibition of distinct caspases

    Quinn L. Deveraux;Natalie Roy;Henning R. Stennicke;Todd Van Arsdale

  • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme.

    T Fernandes-Alnemri;G Litwack;E S Alnemri

  • Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

    Jia-Lun Wang;Dongxiang Liu;Zhi-Jia Zhang;Simei Shan

  • Autoactivation of Procaspase-9 by Apaf-1-Mediated Oligomerization

    Srinivasa M. Srinivasula;Manzoor Ahmad;Teresa Fernandes-Alnemri;Emad S. Alnemri

  • A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

    Srinivasa M. Srinivasula;Ramesh Hegde;Ayman Saleh;Pinaki Datta

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.

    Corey Rogers;Teresa Fernandes-Alnemri;Lindsey Mayes;Diana Alnemri

  • The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

    Fernandes-Alnemri T;Wu J;Yu Jw;Datta P

  • Negative regulation of the Apaf-1 apoptosome by Hsp70.

    Ayman Saleh;Srinivasa M. Srinivasula;Levent Balkir;Paul D. Robbins

  • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

    Teresa Fernandes-Alnemri;Je-Wook Yu;Jianghong Wu;Pinaki Datta

Frequent Co-Authors

Teresa Fernandes-Alnemri
Teresa Fernandes-Alnemri Thomas Jefferson University
Srinivasa M. Srinivasula
Srinivasa M. Srinivasula Indian Institute of Science Education and Research, Thiruvananthapuram
Gerald Litwack
Gerald Litwack Texas A&M Health Science Center
Sharad Kumar
Sharad Kumar University of Adelaide
Oliver Kepp
Oliver Kepp Institut Gustave Roussy
Kevin J. Tomaselli
Kevin J. Tomaselli Pfizer (United States)
Lorenzo Galluzzi
Lorenzo Galluzzi Cornell University
Gabriel Núñez
Gabriel Núñez University of Michigan–Ann Arbor
Peter Vandenabeele
Peter Vandenabeele Ghent University
Gerry Melino
Gerry Melino University of Rome Tor Vergata

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