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Teresa Fernandes-Alnemri

Teresa Fernandes-Alnemri

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
32013
World Ranking
9954
National Ranking
4358

Overview

Teresa Fernandes-Alnemri is affiliated with Thomas Jefferson University in the United States. Their research primarily focuses on the biochemical and molecular biological aspects of inflammasomes, ion transport mechanisms, and immune disorders.

Their main fields of study include Biochemistry, Genetics and Molecular Biology, with a specialization in Molecular Biology as a subfield. The central themes of their work cover inflammasome and immune disorders, ion transport and channel regulation, and heme oxygenase-1 and carbon monoxide.

Teresa Fernandes-Alnemri's recent publications include the following:

  • Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis, 2021, published in Nature Communications
  • Pyroptosis modulates multiple immune cell populations in targeted therapy-treated melanoma, 2025, published in Cancer Immunology Research

The scientist frequently collaborates with several researchers, including Lindsey Mayes, A. Enache, Jian Xie, Chou-Long Huang, and Robert Köchl.

Their work is often published in venues such as Nature Communications and Cancer Immunology Research, which are aligned with their fields of biochemical and immunological research interests.

Best Publications

  • Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.

    Franz G. Bauernfeind;Gabor Horvath;Andrea Stutz;Emad S. Alnemri

  • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

    Teresa Fernandes-Alnemri;Je-Wook Yu;Pinaki Datta;Jianghong Wu

  • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme.

    T Fernandes-Alnemri;G Litwack;E S Alnemri

  • Autoactivation of Procaspase-9 by Apaf-1-Mediated Oligomerization

    Srinivasa M. Srinivasula;Manzoor Ahmad;Teresa Fernandes-Alnemri;Emad S. Alnemri

  • A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

    Srinivasa M. Srinivasula;Ramesh Hegde;Ayman Saleh;Pinaki Datta

  • Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.

    Corey Rogers;Teresa Fernandes-Alnemri;Lindsey Mayes;Diana Alnemri

  • The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

    Fernandes-Alnemri T;Wu J;Yu Jw;Datta P

  • In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.

    Teresa Fernandes-Alnemri;Robert C. Armstrong;Joseph Krebs;Srinivasa M. Srinivasula

  • Identification of Omi/HtrA2 as a Mitochondrial Apoptotic Serine Protease That Disrupts Inhibitor of Apoptosis Protein-Caspase Interaction

    Ramesh Hegde;Srinivasa M. Srinivasula;ZhiJia Zhang;Richard Wassell

  • The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

    Teresa Fernandes-Alnemri;Je-Wook Yu;Je-Wook Yu;Christine Juliana;Leobaldo Solorzano

  • Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation

    Christine Juliana;Teresa Fernandes-Alnemri;Seokwon Kang;Andrew Farias

  • Identification and Molecular Cloning of Two Novel Receptors for the Cytotoxic Ligand TRAIL

    Marion MacFarlane;Manzoor Ahmad;Srinivasa M. Srinivasula;Teresa Fernandes-Alnemri

  • Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases

    Srinivasa M. Srinivasula;Manzoor Ahmad;Teresa Fernandes-Alnemri;Gerald Litwack

  • Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria.

    Yin Guo;Srinivasa M. Srinivasula;Anne Druilhe;Teresa Fernandes-Alnemri

  • Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis.

    Atsushi Takahashi;Emad S. Alnemri;Yuri A. Lazebnik;Yuri A. Lazebnik;Teresa Fernandes-Alnemri

  • Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome

    Christine Juliana;Teresa Fernandes-Alnemri;Jianghong Wu;Pinaki Datta

  • Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation.

    Corey Rogers;Dan A. Erkes;Alexandria Nardone;Andrew E. Aplin

  • Mch2, a New Member of the Apoptotic Ced-3/Ice Cysteine Protease Gene Family

    Teresa Fernandes-Alnemri;Gerald Litwack;Emad S. Alnemri

  • Identification of Ipaf, a Human Caspase-1-activating Protein Related to Apaf-1

    Jean-Luc Poyet;Srinivasa M. Srinivasula;Mehdi Tnani;Marjaneh Razmara

  • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

    Teresa Fernandes-Alnemri;Je-Wook Yu;Jianghong Wu;Pinaki Datta

Frequent Co-Authors

Emad S. Alnemri
Emad S. Alnemri Thomas Jefferson University
Srinivasa M. Srinivasula
Srinivasa M. Srinivasula Indian Institute of Science Education and Research, Thiruvananthapuram
Gerald Litwack
Gerald Litwack Texas A&M Health Science Center
Kevin J. Tomaselli
Kevin J. Tomaselli Pfizer (United States)
Yigong Shi
Yigong Shi Westlake University
Eicke Latz
Eicke Latz German Rheumatism Research Centre
William C. Earnshaw
William C. Earnshaw University of Edinburgh
Carlo M. Croce
Carlo M. Croce The Ohio State University
Katherine A. Fitzgerald
Katherine A. Fitzgerald University of Massachusetts Chan Medical School
Joseph A. Trapani
Joseph A. Trapani Peter MacCallum Cancer Centre

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