What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Apoptosis, Cell biology, Biochemistry, Cancer research and Molecular biology.
His Cell biology study incorporates themes from Cancer cell, Fas receptor, Jurkat cells and Fas ligand.
In his research on the topic of Biochemistry, Topoisomerase is strongly related with Etoposide.
His Cancer research research includes elements of Protein kinase B, Immunology, Bone marrow, Kinase activity and PI3K/AKT/mTOR pathway.
The Molecular biology study combines topics in areas such as Camptothecin, Cell culture, Daunorubicin and Blot.
The various areas that he examines in his Programmed cell death study include Proteases and Carcinogenesis.
His most cited work include:
- Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis (2532 citations)
- Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE (2366 citations)
- Specific Proteolytic Cleavage of Poly(ADP-ribose) Polymerase: An Early Marker of Chemotherapy-induced Apoptosis (1659 citations)
What are the main themes of his work throughout his whole career to date?
Scott H. Kaufmann mostly deals with Cancer research, Apoptosis, Molecular biology, Internal medicine and Cell biology.
Scott H. Kaufmann has researched Cancer research in several fields, including Cancer, Ovarian cancer, PARP inhibitor and Leukemia, Immunology.
Apoptosis is frequently linked to Jurkat cells in his study.
Scott H. Kaufmann combines subjects such as Cell culture, Topoisomerase, Biochemistry and Poly ADP ribose polymerase with his study of Molecular biology.
His research integrates issues of Gastroenterology, Surgery and Oncology in his study of Internal medicine.
He has included themes like Proteases, Cancer cell, DNA damage and Inhibitor of apoptosis in his Cell biology study.
He most often published in these fields:
- Cancer research (40.19%)
- Apoptosis (28.19%)
- Molecular biology (23.24%)
What were the highlights of his more recent work (between 2014-2021)?
- Cancer research (40.19%)
- Ovarian cancer (8.76%)
- Internal medicine (18.29%)
In recent papers he was focusing on the following fields of study:
His main research concerns Cancer research, Ovarian cancer, Internal medicine, PARP inhibitor and Oncology.
His Cancer research research is multidisciplinary, relying on both Ovarian carcinoma, RAD51C, Leukemia and DNA repair.
His research in Leukemia intersects with topics in Apoptosis and Refractory.
His Apoptosis research incorporates elements of Venetoclax, Jurkat cells and Cell biology.
His work focuses on many connections between Internal medicine and other disciplines, such as Veliparib, that overlap with his field of interest in Mucositis and Chronic myelomonocytic leukemia.
His studies deal with areas such as Molecular biology and Germline as well as Germline mutation.
Between 2014 and 2021, his most popular works were:
- Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial (538 citations)
- Poly (ADP-Ribose) Polymerase Inhibitors: Recent Advances and Future Development (220 citations)
- Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma. (139 citations)
In his most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Cancer research, PARP inhibitor, Apoptosis, Ovarian cancer and Cell biology.
His Cancer research study combines topics in areas such as Mutation, Carboplatin, PARP1, Molecular biology and Leukemia.
The concepts of his Molecular biology study are interwoven with issues in Carcinogenesis, Phenotype, Genome instability, Topoisomerase and Progeria.
The study incorporates disciplines such as Germline mutation, RAD51C, Olaparib, Poly Polymerase Inhibitor and Rucaparib in addition to PARP inhibitor.
His Apoptosis study combines topics from a wide range of disciplines, such as Venetoclax and Jurkat cells.
His Cell biology research includes themes of Tyrosine, Ubiquitin ligase, Programmed cell death and Puma.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
