World's Best Scientists 2026 revealed!
Yung Hyun Choi

Yung Hyun Choi

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Biology and Biochemistry
Korea
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
95
Citations
34729
World Ranking
1895
National Ranking
9

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Korea Leader Award
  • 2025 - Research.com Biology and Biochemistry in Korea Leader Award

Overview

Yung Hyun Choi is affiliated with Dong-Eui University in South Korea and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research primarily focuses on molecular biology, pharmacology, immunology, oncology, and plant science. Choi's work frequently centers on topics such as genomics, phytochemicals, oxidative stress, natural product bioactivities and synthesis, pharmacological effects of natural compounds, phytochemicals and antioxidant activities, heme oxygenase-1 and carbon monoxide, autophagy in disease and therapy, and immune response and inflammation.

The following recent publications exemplify their research contributions:

  • The regulation of the TLR4/NF-κB and Nrf2/HO-1 signaling pathways is involved in the inhibition of lipopolysaccharide-induced inflammation and oxidative reactions by morroniside in RAW 264.7 macrophages (2021, Archives of Biochemistry and Biophysics)
  • Diesel particulate matter2.5 promotes epithelial-mesenchymal transition of human retinal pigment epithelial cells via generation of reactive oxygen species (2020, Environmental Pollution)
  • Attenuation of Lipopolysaccharide-Induced Inflammatory Responses through Inhibition of the NF-κB Pathway and the Increased NRF2 Level by a Flavonol-Enriched n-Butanol Fraction from Uvaria alba (2023, ACS Omega)
  • Coptisine induces autophagic cell death through down-regulation of PI3K/Akt/mTOR signaling pathway and up-regulation of ROS-mediated mitochondrial dysfunction in hepatocellular carcinoma Hep3B cells (2020, Archives of Biochemistry and Biophysics)
  • Anthocyanins isolated from Hibiscus syriacus L. attenuate lipopolysaccharide-induced inflammation and endotoxic shock by inhibiting the TLR4/MD2-mediated NF-κB signaling pathway (2020, Phytomedicine)

The primary venues in which Choi frequently publishes include:

  • International Journal of Molecular Sciences
  • Biomolecules & Therapeutics
  • Antioxidants
  • Genes & Genomics
  • Biotechnology and Bioprocess Engineering

Collaborative efforts have seen repeated partnerships with several co-authors, including:

  • Gi-Young Kim
  • Hyesook Lee
  • Cheol Park
  • Hyun Hwangbo
  • Su Hyun Hong

Choi's scientific work integrates biochemical pathways and molecular mechanisms, especially focusing on signaling pathways like NF-κB, Nrf2/HO-1, and PI3K/Akt/mTOR. The investigations often explore the anti-inflammatory, antioxidant, and autophagic effects of natural compounds and phytochemicals, contributing to the understanding of disease mechanisms and potential therapeutic approaches.

Best Publications

  • Anti-inflammatory effects of fucoidan through inhibition of NF-κB, MAPK and Akt activation in lipopolysaccharide-induced BV2 microglia cells

    Hye Young Park;Min Ho Han;Cheol Park;Cheng-Yun Jin

  • Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis.

    Mei Jing Piao;Mee Jung Ahn;Kyoung Ah Kang;Yea Seong Ryu

  • Five-lipoxygenase inhibitors can mediate apoptosis in human breast cancer cell lines through complex eicosanoid interactions.

    Ingalill Avis;Sung H. Hong;Alfredo Martínez;Terry Moody

  • Involvement of Autophagy in Oncogenic K-Ras-induced Malignant Cell Transformation

    Min Jung Kim;Soo Jung Woo;Chang-Hwan Yoon;Jae Seong Lee

  • Anti-inflammatory effects of β-lapachone in lipopolysaccharide-stimulated BV2 microglia

    Dong-Oh Moon;Yung Hyun Choi;Nam-Duk Kim;Yeong-Min Park

  • Regulation of Cyclin D1 by Calpain Protease

    Yung Hyun Choi;Su Jae Lee;PhuongMai Nguyen;Joung Soon Jang

  • Rosmarinic acid sensitizes cell death through suppression of TNF-α-induced NF-κB activation and ROS generation in human leukemia U937 cells

    Dong-Oh Moon;Mun-Ock Kim;Jae-Dong Lee;Yung Hyun Choi

  • Induction of Bax and activation of caspases during beta-sitosterol-mediated apoptosis in human colon cancer cells.

    Yung Hyun Choi;Kyu Ri Kong;Young Ae Kim;Keun Ok Jung

  • Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells

    Su Jae Lee;Mahn Joon Ha;Jeen Lee;PhuongMai Nguyen

  • Inhibitory effects of eicosapentaenoic acid on lipopolysaccharide-induced activation in BV2 microglia

    Dong-Oh Moon;Ki-Cheon Kim;Cheng-Yun Jin;Min-Ho Han

  • Resveratrol inhibits cell proliferation and induces apoptosis of human breast carcinoma MCF-7 cells.

    Young-Ae Kim;Byung Tae Choi;Yong Tae Lee;Dong Il Park

  • Butein induces G2/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation

    Dong-Oh Moon;Mun-Ock Kim;Yung Hyun Choi;Jin Won Hyun

  • Genistein-induced G2/M arrest is associated with the inhibition of cyclin B1 and the induction of p21 in human breast carcinoma cells.

    Yung Hyun Choi;Lijuan Zhang;Won Ho Lee;K.-Y. Park

  • Cell-free microRNAs in urine as diagnostic and prognostic biomarkers of bladder cancer.

    Seok Joong Yun;Pildu Jeong;Won-Tae Kim;Tae Hwan Kim

  • β-Sitosterol Induces Anti-proliferation and Apoptosis in Human Leukemic U937 Cells through Activation of Caspase-3 and Induction of Bax/Bcl-2 Ratio

    Cheol Park;Dong-Oh Moon;Chung-Ho Rhu;Byung Tae Choi

  • Anti-inflammatory effects of cordycepin via suppression of inflammatory mediators in BV2 microglial cells.

    Jin-Woo Jeong;Cheng-Yun Jin;Gi-Young Kim;Jae-Dong Lee

  • Effects of adenovirus-mediated p16INK4A expression on cell cycle arrest are determined by endogenous p16 and Rb status in human cancer cells.

    Caroline Craig;Min Kim;Ekta Ohri;Robert Wersto

  • DIFFERENTIAL INHIBITORY EFFECTS OF BAICALEIN AND BAICALIN ON LPS-INDUCED CYCLOOXYGENASE-2 EXPRESSION THROUGH INHIBITION OF C/EBPBETA DNA-BINDING ACTIVITY

    Kyung Jin Woo;Jun Hee Lim;Seong-Il Suh;Young-Kyu Kwon

  • Curcumin attenuates the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated BV2 microglia.

    Cheng-yun Jin;Jae-dong Lee;Cheol Park;Yung hyun Choi

  • Sulforaphane suppresses TNF-α-mediated activation of NF-κB and induces apoptosis through activation of reactive oxygen species-dependent caspase-3

    Dong-Oh Moon;Mun-Ock Kim;Sang-Hyuck Kang;Yung Hyun Choi

Frequent Co-Authors

Gi-Young Kim
Gi-Young Kim Jeju National University
Wun-Jae Kim
Wun-Jae Kim Chungbuk National University
Il-Whan Choi
Il-Whan Choi Inje University
Taeg Kyu Kwon
Taeg Kyu Kwon Keimyung University
Jin Won Hyun
Jin Won Hyun Jeju National University
Dae Sung Lee
Dae Sung Lee Kyungpook National University
Won-Kyo Jung
Won-Kyo Jung Pukyong National University
You-Jin Jeon
You-Jin Jeon Jeju National University
Hae Young Chung
Hae Young Chung Pusan National University
Jong-Wook Park
Jong-Wook Park Keimyung University

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