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Biology and Biochemistry

D-Index
72
Citations
17222
World Ranking
6358
National Ranking
54

Overview

Jin Won Hyun is affiliated with Jeju National University in South Korea and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research emphasizes molecular biology, health, toxicology, mutagenesis, dermatology, cell biology, and biochemistry.

The scientist's work engages with several key topics, including:

  • Air Quality and Health Impacts
  • Genomics, phytochemicals, and oxidative stress
  • Skin Protection and Aging
  • Antioxidant Activity and Oxidative Stress
  • Heme Oxygenase-1 and Carbon Monoxide
  • Hair Growth and Disorders
  • Autophagy in Disease and Therapy

Jin Won Hyun has coauthored frequently with a number of researchers, among them:

  • Mei Jing Piao
  • Pincha Devage Sameera Madushan Fernando
  • Herath Mudiyanselage Udari Lakmini Herath
  • Kyoung Ah Kang
  • Yung Hyun Choi

Their work appears in several recurring publication venues, predominantly in journals such as:

  • Biomolecules & Therapeutics
  • Antioxidants
  • International Journal of Medical Sciences
  • Nutrients
  • Anticancer Research

Recent publications illustrate the breadth of their research interests and include:

  • Diesel particulate matter2.5 promotes epithelial-mesenchymal transition of human retinal pigment epithelial cells via generation of reactive oxygen species, 2020, Environmental Pollution
  • Auranofin Enhances Sulforaphane-Mediated Apoptosis in Hepatocellular Carcinoma Hep3B Cells through Inactivation of the PI3K/Akt Signaling Pathway, 2020, Biomolecules & Therapeutics
  • Hesperidin Exhibits Protective Effects against PM2.5-Mediated Mitochondrial Damage, Cell Cycle Arrest, and Cellular Senescence in Human HaCaT Keratinocytes, 2022, Molecules
  • Extract of Cornus officinalis Protects Keratinocytes from Particulate Matter-induced Oxidative Stress, 2020, International Journal of Medical Sciences
  • Vanillic Acid Stimulates Anagen Signaling via the PI3K/Akt/ β-Catenin Pathway in Dermal Papilla Cells, 2020, Biomolecules & Therapeutics

Best Publications

  • Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis

    Mei Jing Piao;Kyoung Ah Kang;In Kyung Lee;Hye Sun Kim

  • (-)-Epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PI3K and ERK in human mammary epithelial cells.

    Hye-Kyung Na;Eun-Hee Kim;Joo-Hee Jung;Hyun-Hee Lee

  • Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis.

    Mei Jing Piao;Mee Jung Ahn;Kyoung Ah Kang;Yea Seong Ryu

  • Curcumin suppresses phorbol ester-induced matrix metalloproteinase-9 expression by inhibiting the PKC to MAPK signaling pathways in human astroglioma cells.

    Moon Sook Woo;Soo Hyun Jung;So Young Kim;Jin Won Hyun

  • Cytoprotective effect of phloroglucinol on oxidative stress induced cell damage via catalase activation.

    Kyoung Ah Kang;Kyoung Hwa Lee;Sungwook Chae;Rui Zhang

  • Eckol isolated from Ecklonia cava attenuates oxidative stress induced cell damage in lung fibroblast cells.

    Kyoung Ah Kang;Kyoung Hwa Lee;Sungwook Chae;Rui Zhang

  • Up-regulation of Nrf2-mediated heme oxygenase-1 expression by eckol, a phlorotannin compound, through activation of Erk and PI3K/Akt.

    Ki Cheon Kim;Kyoung Ah Kang;Rui Zhang;Mei Jing Piao

  • Anti-inflammatory mechanism of ginseng saponins in activated microglia

    Jin Sun Park;Eun Mi Park;Dong Hyun Kim;Kangsik Jung

  • Endoplasmic reticulum stress signaling is involved in silver nanoparticles-induced apoptosis.

    Rui Zhang;Mei Jing Piao;Ki Cheon Kim;Areum Daseul Kim

  • Butein induces G2/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation

    Dong-Oh Moon;Mun-Ock Kim;Yung Hyun Choi;Jin Won Hyun

  • Luteolin promotes apoptotic cell death via upregulation of Nrf2 expression by DNA demethylase and the interaction of Nrf2 with p53 in human colon cancer cells

    Kyoung Ah Kang;Mei Jing Piao;Yu Jae Hyun;Ao Xuan Zhen

  • Anti-Inflammatory Mechanism of Compound K in Activated Microglia and Its Neuroprotective Effect on Experimental Stroke in Mice

    Jin Sun Park;Jin A. Shin;Ji Sun Jung;Jin Won Hyun

  • Anti-Inflammatory Mechanisms of Isoflavone Metabolites in Lipopolysaccharide-Stimulated Microglial Cells

    Jin Sun Park;Moon Sook Woo;Dong Hyun Kim;Jin Won Hyun

  • Effect of Compound K, a Metabolite of Ginseng Saponin, Combined with γ-Ray Radiation in Human Lung Cancer Cells in Vitro and in Vivo

    Sungwook Chae;Kyoung Ah Kang;Weon Young Chang;Min Jung Kim

  • Luteolin induces apoptotic cell death via antioxidant activity in human colon cancer cells

    Kyoung Ah Kang;Mei Jing Piao;Yea Seong Ryu;Yu Jae Hyun

  • Hyperoside prevents oxidative damage induced by hydrogen peroxide in lung fibroblast cells via an antioxidant effect.

    Mei Jing Piao;Kyoung Ah Kang;Rui Zhang;Dong Ok Ko

  • Ginseng saponin metabolite suppresses phorbol ester-induced matrix metalloproteinase-9 expression through inhibition of activator protein-1 and mitogen-activated protein kinase signaling pathways in human astroglioma cells.

    Soo Hyun Jung;Moon Sook Woo;So Young Kim;Won Ki Kim

  • Epigenetic changes induced by oxidative stress in colorectal cancer cells: methylation of tumor suppressor RUNX3

    Kyoung Ah Kang;Rui Zhang;Gi Young Kim;Suk Chul Bae

  • Particulate matter induces inflammatory cytokine production via activation of NFκB by TLR5-NOX4-ROS signaling in human skin keratinocyte and mouse skin.

    Yea Seong Ryu;Kyoung Ah Kang;Mei Jing Piao;Mee Jung Ahn

  • Myricetin protects cells against oxidative stress-induced apoptosis via regulation of PI3K/Akt and MAPK signaling pathways.

    Kyoung Ah Kang;Zhi Hong Wang;Rui Zhang;Mei Jing Piao

Frequent Co-Authors

Gi-Young Kim
Gi-Young Kim Jeju National University
Dong-Hyun Kim
Dong-Hyun Kim Kyung Hee University
Yung Hyun Choi
Yung Hyun Choi Dong-Eui University
Hee-Sun Kim
Hee-Sun Kim Ewha Womans University
Sam Sik Kang
Sam Sik Kang Seoul National University
Su Jae Lee
Su Jae Lee Hanyang University
Changjong Moon
Changjong Moon Chonnam National University
Yun-Sil Lee
Yun-Sil Lee Ewha Womans University
Wun-Jae Kim
Wun-Jae Kim Chungbuk National University
Jinhee Choi
Jinhee Choi University of Seoul

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