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Jong-Wook Park

Jong-Wook Park

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
10070
World Ranking
13378
National Ranking
156

Overview

Jong-Wook Park is affiliated with Keimyung University in South Korea. Their research spans several fields primarily within medicine and biochemistry, genetics, and molecular biology, reflecting a focus on understanding biological mechanisms at the molecular and cellular levels.

The main fields of study associated with their work include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, Jong-Wook Park's subfields of study highlight specialization areas such as:

  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Oncology
  • Radiology, Nuclear Medicine and Imaging
  • Genetics

The topics frequently addressed in their publications provide insight into their research interests and areas of expertise:

  • Cancer-related Molecular Pathways
  • Ubiquitin and proteasome pathways
  • Monetary Policy and Economic Impact
  • Prostate Cancer Treatment and Research
  • Radiopharmaceutical Chemistry and Applications
  • Cell death mechanisms and regulation
  • Genetics and Neurodevelopmental Disorders

Jong-Wook Park has contributed to various scholarly articles, notable recent publications include:

  • Inhibition of USP1 enhances anticancer drugs-induced cancer cell death through downregulation of survivin and miR-216a-5p-mediated upregulation of DR5, 2022, Cell Death and Disease
  • Inhibition of cathepsin K sensitizes oxaliplatin-induced apoptotic cell death by Bax upregulation through OTUB1-mediated p53 stabilization in vitro and in vivo, 2021, Oncogene
  • A microdose clinical trial to evaluate [18F]Florastamin as a positron emission tomography imaging agent in patients with prostate cancer, 2020, European Journal of Nuclear Medicine and Molecular Imaging
  • Identifying monetary policy shocks using economic forecasts in Korea, 2022, Economic Modelling
  • Dexamethasone Inhibits TRAIL-Induced Apoptosis through c-FLIP(L) Upregulation and DR5 Downregulation by GSK3β Activation in Cancer Cells, 2020, Cancers

Their research has been published in various venues with the most frequent being:

  • The Korea Journal of Sport
  • Cell Death and Disease
  • Oncogene
  • International Journal of Molecular Sciences
  • Economic Modelling

Jong-Wook Park frequently collaborates with several co-authors, indicating a network of ongoing research partnerships. The most frequent co-authors are:

  • Shin Kim
  • Taeg Kyu Kwon
  • Seon Min Woo
  • Seung Un Seo
  • Kyoung-jin Min

Best Publications

  • Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt

    Ju Hyung Woo;Young Ho Kim;Yun Jung Choi;Dae Gon Kim

  • Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5)

    Eun Mi Jung;Jun Hee Lim;Tae Jin Lee;Jong-Wook Park

  • Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC δ signal transduction

    Ju Hyung Woo;Jun Hee Lim;Young Ho Kim;Seong Il Suh

  • Chrysin-induced apoptosis is mediated through caspase activation and Akt inactivation in U937 leukemia cells.

    Kyung Jin Woo;Yong-Jin Jeong;Jong-Wook Park;Taeg Kyu Kwon

  • Chrysin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression through the inhibition of nuclear factor for IL-6 (NF-IL6) DNA-binding activity.

    Kyung Jin Woo;Yong-Jin Jeong;Hiroyasu Inoue;Jong-Wook Park

  • Chemopreventive agent resveratrol, a natural product derived from grapes, reversibly inhibits progression through S and G2 phases of the cell cycle in U937 cells

    Jong-Wook Park;Yun-Jung Choi;Min-Ah Jang;Young-Sun Lee

  • Quercetin arrests G2/M phase and induces caspase-dependent cell death in U937 cells

    Tae-Jin Lee;On Hee Kim;Yeoun Hee Kim;Jun Hee Lim

  • Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells.

    Young-Ho Kim;Jong-Wook Park;Jai-Youl Lee;Taeg Kyu Kwon

  • Bcl-2 overexpression attenuates resveratrol-induced apoptosis in U937 cells by inhibition of caspase-3 activity

    Jong Wook Park;Yun Jung Choi;Seong Il Suh;Won Ki Baek

  • DIFFERENTIAL INHIBITORY EFFECTS OF BAICALEIN AND BAICALIN ON LPS-INDUCED CYCLOOXYGENASE-2 EXPRESSION THROUGH INHIBITION OF C/EBPBETA DNA-BINDING ACTIVITY

    Kyung Jin Woo;Jun Hee Lim;Seong-Il Suh;Young-Kyu Kwon

  • Sanguinarine‐induced apoptosis: Generation of ROS, down‐regulation of Bcl‐2, c‐FLIP, and synergy with TRAIL

    Shin Kim;Tae-Jin Lee;Jaechan Leem;Kyeong Sook Choi

  • Triptolide inhibits murine-inducible nitric oxide synthase expression by down-regulating lipopolysaccharide-induced activity of nuclear factor-κB and c-Jun NH2-terminal kinase

    Young-Ho Kim;Sang-Han Lee;Jai-Youl Lee;Sang-Won Choi

  • Significance of 18F‐fluorodeoxyglucose positron‐emission tomography/computed tomography for the postoperative surveillance of advanced renal cell carcinoma

    Jong Wook Park;Moon Ki Jo;Hyun Moo Lee

  • Induction of apoptosis by withaferin A in human leukemia U937 cells through down-regulation of Akt phosphorylation.

    Jung Hwa Oh;Tae-Jin Lee;Sang Hyun Kim;Yung Hyun Choi

  • Prospective evaluation of 3-T MRI performed before initial transrectal ultrasound-guided prostate biopsy in patients with high prostate-specific antigen and no previous biopsy.

    Byung Kwan Park;Jong Wook Park;Seo Yong Park;Chan Kyo Kim

  • Ruthenium red, inhibitor of mitochondrial Ca2+ uniporter, inhibits curcumin-induced apoptosis via the prevention of intracellular Ca2+ depletion and cytochrome c release.

    Jae Hoon Bae;Jong-Wook Park;Taeg Kyu Kwon

  • Desferrioxamine, an iron chelator, enhances HIF-1α accumulation via cyclooxygenase-2 signaling pathway

    Kyung Jin Woo;Tae-Jin Lee;Jong-Wook Park;Taeg Kyu Kwon

  • Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP.

    Tae Jin Lee;Hee Jung Um;Do Sik Min;Jong Wook Park

  • Arsenic trioxide induces G2/M growth arrest and apoptosis after caspase-3 activation and bcl-2 phosphorylation in promonocytic U937 cells.

    Jong-Wook Park;Yun-Jung Choi;Min Ah Jang;Suk-Hwan Baek

  • Withaferin A inhibits iNOS expression and nitric oxide production by Akt inactivation and down-regulating LPS-induced activity of NF-κB in RAW 264.7 cells

    Jung Hwa Oh;Tae-Jin Lee;Jong-Wook Park;Taeg Kyu Kwon

Frequent Co-Authors

Taeg Kyu Kwon
Taeg Kyu Kwon Keimyung University
Young Ho Kim
Young Ho Kim Kyungpook National University
Yung Hyun Choi
Yung Hyun Choi Dong-Eui University
Kyeong Sook Choi
Kyeong Sook Choi Ajou University
Do Sik Min
Do Sik Min Yonsei University
Dong-Eun Kim
Dong-Eun Kim Konkuk University
Jihye Paik
Jihye Paik Cornell University
Edward Gabrielson
Edward Gabrielson Johns Hopkins University School of Medicine
Seung Soon Im
Seung Soon Im Hanyang University
Sung Young Park
Sung Young Park Korea National University of Transportation

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