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Biology and Biochemistry
Taiwan
2025

D-Index & Metrics

Biology and Biochemistry

D-Index
86
Citations
25562
World Ranking
2984
National Ranking
11

Medicine

D-Index
86
Citations
25709
World Ranking
14187
National Ranking
31

Research.com Recognitions

  • 2025 - Research.com Biology and Biochemistry in Taiwan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Taiwan Leader Award
  • 2022 - Research.com Biology and Biochemistry in Taiwan Leader Award

Overview

Jing Gung Chung is affiliated with China Medical University in Taiwan and has contributed to fields primarily within Biochemistry, Genetics and Molecular Biology as well as Medicine. Their research encompasses significant subfields including Molecular Biology, Pharmacology, Organic Chemistry, Immunology, and Complementary and Alternative Medicine.

The scientist's work frequently appears in publication venues such as Environmental Toxicology, In Vivo, Anticancer Research, Antioxidants, and The American Journal of Chinese Medicine.

Key research topics addressed by Jing Gung Chung include:

  • Genomics, phytochemicals, and oxidative stress
  • Pharmacological Effects of Natural Compounds
  • Synthesis and biological activity
  • Immune Response and Inflammation
  • Natural product bioactivities and synthesis
  • Phytochemistry and biological activity of medicinal plants
  • Bioactive Compounds and Antitumor Agents

Frequent collaborators in Jing Gung Chung's research efforts are:

  • Fei-Ting Hsu
  • Shu-Fen Peng
  • Yi-Ping Huang
  • Wen-Tsong Hsieh
  • Fu-Shin Chueh

Recent papers authored by or involving Jing Gung Chung illustrate a range of biomedical topics, including cardiomyocyte apoptosis, antioxidative pathways, cancer cell apoptosis, and metastasis inhibition:

  • Tetramethylpyrazine reverses high-glucose induced hypoxic effects by negatively regulating HIF-1α induced BNIP3 expression to ameliorate H9c2 cardiomyoblast apoptosis, 2020, Nutrition & Metabolism
  • Imperatorin Interferes with LPS Binding to the TLR4 Co-Receptor and Activates the Nrf2 Antioxidative Pathway in RAW264.7 Murine Macrophage Cells, 2021, Antioxidants
  • Astragaloside IV Induces Apoptosis, G1-Phase Arrest and Inhibits Anti-apoptotic Signaling in Hepatocellular Carcinoma, 2020, In Vivo
  • Glycyrrhizic Acid Modulates Apoptosis through Extrinsic/Intrinsic Pathways and Inhibits Protein Kinase B- and Extracellular Signal-Regulated Kinase-Mediated Metastatic Potential in Hepatocellular Carcinoma In Vitro and In Vivo, 2020, The American Journal of Chinese Medicine
  • Melittin suppresses epithelial-mesenchymal transition and metastasis in human gastric cancer AGS cells via regulating Wnt/BMP associated pathway, 2021, Bioscience Biotechnology and Biochemistry

Best Publications

  • Quercetin-mediated Cell Cycle Arrest and Apoptosis Involving Activation of a Caspase Cascade through the Mitochondrial Pathway in Human Breast Cancer MCF-7 Cells

    Chu Chung Chou;Jai Sing Yang;Hsu Feng Lu;Siu Wan Ip

  • Quercetin-induced apoptosis acts through mitochondrial- and caspase-3-dependent pathways in human breast cancer MDA-MB-231 cells.

    Su Yu Chien;Yao Chung Wu;Jing Gung Chung;Jai Sing Yang

  • Curcumin Induces Apoptosis in Human Non-small Cell Lung Cancer NCI-H460 Cells through ER Stress and Caspase Cascade- and Mitochondria-dependent Pathways

    Shin Hwar Wu;Liang Wen Hang;Jai Sing Yang;Hung Yi Chen

  • Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF)

    Song Shei Lin;Kuang Chi Lai;Shu Chun Hsu;Jai Sing Yang

  • Gallic acid induces apoptosis via caspase-3 and mitochondrion-dependent pathways in vitro and suppresses lung xenograft tumor growth in vivo.

    Bin-Chuan Ji;Wu-Huei Hsu;Jai-Sing Yang;Te-Chun Hsia

  • Curcumin-induced Apoptosis of Human Colon Cancer Colo 205 Cells through the Production of ROS, Ca2+ and the Activation of Caspase-3

    Chin Cheng Su;Jaung Geng Lin;Te Mao Li;Jing Gung Chung

  • Danthron, an Anthraquinone Derivative, Induces DNA Damage and Caspase Cascades-Mediated Apoptosis in SNU-1 Human Gastric Cancer Cells through Mitochondrial Permeability Transition Pores and Bax-Triggered Pathways

    Jo Hua Chiang;Jai Sing Yang;Chia Yu Ma;Mei Due Yang

  • INHIBITION OF LUNG CANCER CELL GROWTH BY QUERCETIN GLUCURONIDES VIA G2/M ARREST AND INDUCTION OF APOPTOSIS

    Jen Hung Yang;Te Chun Hsia;Hsiu Maan Kuo;Pei Dawn Lee Chao

  • Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells

    Chi Cheng Lu;Jai Sing Yang;An Cheng Huang;Te Chun Hsia

  • DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma A-549 cells through the activation caspases cascade- and mitochondrial-dependent pathway

    Song Shei Lin;Hsuan Pang Huang;Jai Sing Yang;Jeng Yuan Wu

  • Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathway in human osteosarcoma U-2 OS cells.

    Wen Wen Huang;Yu Jen Chiu;Ming Jen Fan;Hsu Feng Lu

  • Benzyl Isothiocyanate (BITC) Inhibits Migration and Invasion of Human Colon Cancer HT29 Cells by Inhibiting Matrix Metalloproteinase-2/-9 and Urokinase Plasminogen (uPA) through PKC and MAPK Signaling Pathway

    Kuang-Chi Lai;An-Cheng Huang;Shu-Chun Hsu;Chao-Lin Kuo

  • Berberine induces cell cycle arrest and apoptosis in human gastric carcinoma SNU-5 cell line.

    Jing Pin Lin;Jai Sing Yang;Jau Hong Lee;Wen Tsong Hsieh

  • Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-κB, u-PA and MMP-2 and -9

    Yung Tsuan Ho;Jai Sing Yang;Tsai Chung Li;Jen Jyh Lin

  • Ellagic acid induced p53/p21 expression, G1 arrest and apoptosis in human bladder cancer T24 cells.

    Te Mao Li;Guang Wei Chen;Chin Cheng Su;Jaung Gung Lin

  • Capsaicin-induced apoptosis in human hepatoma HepG2 cells.

    Shang Pang Huang;Jung Chou Chen;Chih Chung Wu;Chi Tsai Chen

  • Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells through the inhibition of gene expression of matrix metalloproteinase-9

    Ya Yin Chen;Su Yin Chiang;Jaung Geng Lin;Yi Shih Ma

  • Curcumin Inhibits Cell Migration of Human Colon Cancer Colo 205 Cells through the Inhibition of Nuclear Factor kappa B /p65 and Down-regulates Cyclooxygenase-2 and Matrix Metalloproteinase-2 Expressions

    Chin Cheng Su;Guang Wei Chen;Jaung Geng Lin;Lii Tzu Wu

  • Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells

    Yung Tsuan Ho;Chi Cheng Lu;Jai Sing Yang;Jo Hua Chiang

  • Differential effects of allyl sulfides from garlic essential oil on cell cycle regulation in human liver tumor cells

    C. C. Wu;Jing-Gung Chung;S. J. Tsai;J. H. Yang

Frequent Co-Authors

Jai Sing Yang
Jai Sing Yang China Medical University
Sheng-Chu Kuo
Sheng-Chu Kuo China Medical University
W. Gibson Wood
W. Gibson Wood University of Minnesota
Fuu Jen Tsai
Fuu Jen Tsai China Medical University
Chang Hai Tsai
Chang Hai Tsai Asian University
Chih-Hsin Tang
Chih-Hsin Tang China Medical University
Kuo Hsiung Lee
Kuo Hsiung Lee University of Minnesota
Che-Ming Teng
Che-Ming Teng National Taiwan University
Tian Shung Wu
Tian Shung Wu National Cheng Kung University
Yueh-Hsiung Kuo
Yueh-Hsiung Kuo China Medical University

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