World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
60
Citations
13107
World Ranking
1962
National Ranking
976

Overview

Jeffrey J. Hayes is affiliated with the University of Rochester Medical Center in the United States. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with a significant focus on medicine. The main fields of study for Hayes include biochemistry, genetics, and molecular biology, which account for the majority of their publications, alongside medicine.

The subfields of Hayes' research encompass molecular biology, infectious diseases, plant science, epidemiology, and oncology. The scientist's work explores a range of topics, notably genomics and chromatin dynamics, RNA research and splicing, antifungal resistance and susceptibility, fungal infections and studies, peptidase inhibition and analysis, RNA and protein synthesis mechanisms, as well as RNA modifications and cancer.

Recent publications demonstrate Hayes' involvement in diverse biological and medical research areas:

  • Unraveling linker histone interactions in nucleosomes (2021) published in Current Opinion in Structural Biology
  • The role of aneuploidy in the emergence of echinocandin resistance in human fungal pathogen Candida albicans (2021) published in PLoS Pathogens
  • Acetylation-modulated communication between the H3 N-terminal tail domain and the intrinsically disordered H1 C-terminal domain (2020) published in Nucleic Acids Research
  • Global histone protein surface accessibility in yeast indicates a uniformly loosely packed genome with canonical nucleosomes (2021) published in Epigenetics & Chromatin
  • Multiple Genes of Candida albicans Influencing Echinocandin Susceptibility in Caspofungin-Adapted Mutants (2022) published in Antimicrobial Agents and Chemotherapy

Hayes frequently publishes in venues such as Nucleic Acids Research, Current Opinion in Structural Biology, PLoS Pathogens, Epigenetics & Chromatin, and Antimicrobial Agents and Chemotherapy. These journals reflect the scientist's interdisciplinary approach, ranging from molecular biology to infectious disease research.

Collaboration is evident in Hayes' work, with notable frequent co-authors including Fanfan Hao, Sudisht K. Sah, Elena Rustchenko, Anshuman Yadav, and Ashok Kumar. These partnerships have contributed to advancing research in areas like chromatin biology and antifungal resistance, showing a consistent pattern of teamwork in their scientific output.

Best Publications

  • A positive role for histone acetylation in transcription factor access to nucleosomal DNA

    Daniel Y. Lee;Jeffrey J. Hayes;Dmitry Pruss;Alan P. Wolffe

  • Chromatin disruption and modification

    Alan P. Wolffe;Jeffrey J. Hayes

  • Identification of additional genes belonging to the LexA regulon in Escherichia coli

    Antonio R. Fernández de Henestrosa;Tomoo Ogi;Sayura Aoyagi;David Chafin

  • The structure of DNA in a nucleosome.

    Jeffrey J. Hayes;Thomas D. Tullius;Alan P. Wolffe

  • A brief review of nucleosome structure

    Amber R. Cutter;Jeffrey J. Hayes

  • Histone contributions to the structure of DNA in the nucleosome.

    Jeffrey J. Hayes;David J. Clark;Alan P. Wolffe

  • Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1

    Jan Bednar;Isabel Garcia-Saez;Ramachandran Boopathi;Amber R. Cutter

  • Hydroxyl radical footprinting.

    Wendy J. Dixon;Jeffrey J. Hayes;Judith R. Levin;Margaret F. Weidner

  • Chromatin in Need of a Fix: Phosphorylation of H2AX Connects Chromatin to DNA Repair

    Christophe Thiriet;Jeffrey J. Hayes

  • (CAG)(n)-hairpin DNA binds to Msh2-Msh3 and changes properties of mismatch recognition.

    Barbara A L Owen;Zungyoon Yang;Maoyi Lai;Maciez Gajek

  • An Asymmetric Model for the Nucleosome: A Binding Site for Linker Histones Inside the DNA Gyres

    Dmitry Pruss;Blaine Bartholomew;Jim Persinger;Jeffrey Hayes

  • Single-base resolution mapping of H1–nucleosome interactions and 3D organization of the nucleosome

    Sajad Hussain Syed;Damien Goutte-Gattat;Nils Becker;Sam Meyer

  • A positive role for nucleosome mobility in the transcriptional activity of chromatin templates: restriction by linker histones.

    K Ura;J J Hayes;A P Wolffe

  • Preferential and asymmetric interaction of linker histones with 5S DNA in the nucleosome

    Jeffrey J. Hayes;Alan P. Wolffe

  • Acetylation mimics within individual core histone tail domains indicate distinct roles in regulating the stability of higher-order chromatin structure.

    Xiaodong Wang;Jeffrey J. Hayes

  • The H4 tail domain participates in intra- and internucleosome interactions with protein and DNA during folding and oligomerization of nucleosome arrays.

    Pu-Yeh Kan;Tamara L. Caterino;Jeffrey J. Hayes

  • Structures and interactions of the core histone tail domains.

    Chunyang Zheng;Jeffrey J. Hayes

  • Nucleosome structural changes due to acetylation.

    William R. Bauer;Jeffrey J. Hayes;James H. White;Alan P. Wolffe

  • Nucleosomal anatomy – where are the histones?

    Dmitry Pruss;Jeffrey J. Hayes;Alan P. Wolffe

  • Replication-independent core histone dynamics at transcriptionally active loci in vivo

    Christophe Thiriet;Jeffrey J. Hayes

Frequent Co-Authors

Alan P. Wolffe
Alan P. Wolffe Sangamo BioSciences (United States)
Thomas D. Tullius
Thomas D. Tullius Boston University
Jeffrey C. Hansen
Jeffrey C. Hansen Colorado State University
Stefan Dimitrov
Stefan Dimitrov Grenoble Alpes University
Paul A. Wade
Paul A. Wade National Institutes of Health
Hitoshi Kurumizaka
Hitoshi Kurumizaka University of Tokyo
Michael Bustin
Michael Bustin National Institutes of Health
Richard Lavery
Richard Lavery Claude Bernard University Lyon 1
Raju Kucherlapati
Raju Kucherlapati Harvard University
Chunlei Guo
Chunlei Guo University of Rochester

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