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Biology and Biochemistry

D-Index
50
Citations
26356
World Ranking
17387
National Ranking
1365

Overview

Fiona M. Menzies is affiliated with the University of Cambridge in the United Kingdom. Their research spans multiple fields including Medicine and Biochemistry, Genetics and Molecular Biology, with focused subfields in Epidemiology, Cell Biology, Physiology, Geriatrics and Gerontology, and Cellular and Molecular Neuroscience.

The scientist's work addresses several main topics, notably:

  • Autophagy in Disease and Therapy
  • Lysosomal Storage Disorders Research
  • Sirtuins and Resveratrol in Medicine
  • Genetic Neurodegenerative Diseases
  • Endoplasmic Reticulum Stress and Disease
  • Hippo pathway signaling and YAP/TAZ

Among recent publications, the following papers are significant:

  • Leucine regulates autophagy via acetylation of the mTORC1 component raptor (2020, Nature Communications)
  • A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy (2020, Developmental Cell)
  • α-Catenin levels determine direction of YAP/TAZ response to autophagy perturbation (2021, Nature Communications)

Frequent co-authors collaborating with Fiona M. Menzies include David C. Rubinsztein, Sung Min Son, Eleanna Stamatakou, Mariella Vicinanza, and Marco M. Manni.

Their work has been published mainly in venues such as Nature Communications and Developmental Cell.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Regulation of Mammalian Autophagy in Physiology and Pathophysiology

    Brinda Ravikumar;Sovan Sarkar;Janet E. Davies;Marie Futter

  • Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

    Fiona M. Menzies;Angeleen Fleming;Andrea Caricasole;Carla F. Bento

  • Lysosomal positioning coordinates cellular nutrient responses

    Viktor I. Korolchuk;Shinji Saiki;Maike Lichtenberg;Farah H. Siddiqi

  • Compromised autophagy and neurodegenerative diseases

    Fiona M. Menzies;Angeleen Fleming;David C. Rubinsztein

  • α-Synuclein impairs macroautophagy: implications for Parkinson’s disease

    Ashley R. Winslow;Chien-Wen Chen;Silvia Corrochano;Abraham Acevedo-Arozena

  • Rapamycin alleviates toxicity of different aggregate-prone proteins.

    Zdenek Berger;Brinda Ravikumar;Fiona M. Menzies;Lourdes Garcia Oroz

  • Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

    Viktor I. Korolchuk;Alicia Mansilla;Fiona M. Menzies;David C. Rubinsztein

  • Mammalian Autophagy: How Does It Work?

    Carla F. Bento;Maurizio Renna;Ghita Ghislat;Claudia Puri

  • Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems

    Viktor I. Korolchuk;Fiona M. Menzies;David C. Rubinsztein

  • The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes.

    Luca Jahreiss;Fiona M Menzies;David C Rubinsztein

  • Autophagy and neurodegeneration.

    Rebecca A. Frake;Thomas Ricketts;Fiona M. Menzies;David C. Rubinsztein

  • The poly(A)-binding protein nuclear 1 suppresses alternative cleavage and polyadenylation sites

    Mathias Jenal;Ran Elkon;Fabricio Loayza-Puch;Gijs van Haaften

  • Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis.

    Fiona M Menzies;Mark R Cookson;Robert W Taylor;Douglass M Turnbull

  • Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications.

    Andrea Williams;Luca Jahreiss;Sovan Sarkar;Shinji Saiki

  • Polyglutamine tracts regulate beclin 1-dependent autophagy

    Avraham Ashkenazi;Carla F. Bento;Thomas Ricketts;Mariella Vicinanza

  • Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3

    Fiona M. Menzies;Jeannette Huebener;Maurizio Renna;Michael Bonin

  • PI(5)P regulates autophagosome biogenesis

    Mariella Vicinanza;Viktor I. Korolchuk;Avraham Ashkenazi;Claudia Puri

  • Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis

    Mariana Pavel;Maurizio Renna;Maurizio Renna;So Jung Park;Fiona M. Menzies

  • Mammalian macroautophagy at a glance.

    Brinda Ravikumar;Marie Futter;Luca Jahreiss;Viktor I. Korolchuk

Frequent Co-Authors

David C. Rubinsztein
David C. Rubinsztein University of Cambridge
Viktor I. Korolchuk
Viktor I. Korolchuk Newcastle University
Cahir J. O'Kane
Cahir J. O'Kane University of Cambridge
Pamela J. Shaw
Pamela J. Shaw University of Sheffield
Sovan Sarkar
Sovan Sarkar University of Birmingham
Mark R. Cookson
Mark R. Cookson National Institutes of Health
Steve D.M. Brown
Steve D.M. Brown Medical Research Council
Pascale Cossart
Pascale Cossart Institut Pasteur
Andrea Ballabio
Andrea Ballabio Baylor College of Medicine
Enza Maria Valente
Enza Maria Valente University of Pavia

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