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Biology and Biochemistry

D-Index
64
Citations
12993
World Ranking
9791
National Ranking
4296

Overview

Ambra Pozzi is affiliated with Vanderbilt University Medical Center in the United States. Their research spans medicine, biochemistry, genetics, and molecular biology, with significant contributions in molecular biology, immunology and allergy, nephrology, genetics, and pharmacology.

Their work covers several main topics, including:

  • Cell Adhesion Molecules Research
  • Renal and related cancers
  • Renal Diseases and Glomerulopathies
  • Eicosanoids and Hypertension Pharmacology
  • Inflammatory mediators and NSAID effects
  • Genetic and Kidney Cyst Diseases
  • Chronic Kidney Disease and Diabetes

Ambra Pozzi has published extensively in notable venues such as:

  • Journal of the American Society of Nephrology (7 publications)
  • Diabetes (4 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)
  • JCI Insight (2 publications)
  • Journal of Clinical Investigation (2 publications)

Frequent co-authors with whom Pozzi has collaborated include:

  • Roy Zent
  • Fabian Bock
  • Xinyu Dong
  • Olga M. Viquez
  • Agnes B. Fogo

Several recent papers authored or co-authored by Ambra Pozzi illustrate the breadth of their research:

  • "DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3," 2021, JCI Insight
  • "Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation," 2022, Journal of Clinical Investigation
  • "Diabetic hyperglycemia promotes primary tumor progression through glycation-induced tumor extracellular matrix stiffening," 2022, Science Advances
  • "International Society of Nephrology first consensus guidance for preclinical animal studies in translational nephrology," 2023, Kidney International
  • "EGF receptor-mediated FUS phosphorylation promotes its nuclear translocation and fibrotic signaling," 2020, The Journal of Cell Biology

Best Publications

  • Elevated matrix metalloprotease and angiostatin levels in integrin α1 knockout mice cause reduced tumor vascularization

    Ambra Pozzi;Philip E. Moberg;Lindsey A. Miles;Simone Wagner

  • The nature and biology of basement membranes.

    Ambra Pozzi;Ambra Pozzi;Peter D. Yurchenco;Renato V. Iozzo

  • The juxtamembrane region of the EGF receptor functions as an activation domain.

    Monica Red Brewer;Sung Hee Choi;Diego Alvarado;Katarina Moravcevic

  • Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo.

    Dana M Brantley;Nikki Cheng;Erin J Thompson;Qing Lin

  • Integrin α1β1 Mediates a Unique Collagen-dependent Proliferation Pathway In Vivo

    Ambra Pozzi;Kishore K. Wary;Filippo G. Giancotti;Humphrey A. Gardner

  • EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation.

    Dana M. Brantley-Sieders;Justin Caughron;Donna Hicks;Ambra Pozzi

  • Discoidin domain receptors in disease.

    Corina M. Borza;Ambra Pozzi;Ambra Pozzi

  • Absence of integrin alpha1beta1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis.

    Humphrey Gardner;Arsi Broberg;Ambra Pozzi;Mattie Laato

  • Transforming Growth Factor β Receptor Type II Inactivation Induces the Malignant Transformation of Intestinal Neoplasms Initiated by Apc Mutation

    Nina M. Muñoz;Melissa Upton;Andres Rojas;Andres Rojas;M. Kay Washington

  • Characterization of 5,6- and 8,9-Epoxyeicosatrienoic Acids (5,6- and 8,9-EET) as Potent in Vivo Angiogenic Lipids

    Ambra Pozzi;Ines Macias-Perez;Tristin Abair;Shouzuo Wei

  • β1 integrin expression by podocytes is required to maintain glomerular structural integrity

    Ambra Pozzi;George Jarad;Gilbert W. Moeckel;Sergio Coffa

  • Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin alpha2beta1 in mice.

    Li Kang;Julio E. Ayala;Robert S. Lee-Young;Zhonghua Zhang

  • Cyclooxygenases and lipoxygenases in cancer.

    Claus Schneider;Ambra Pozzi

  • Low plasma levels of matrix metalloproteinase 9 permit increased tumor angiogenesis.

    Ambra Pozzi;Wendy F LeVine;Humphrey A Gardner

  • Bone morphogenetic protein 4 promotes pulmonary vascular remodeling in hypoxic pulmonary hypertension

    David B. Frank;Amir Abtahi;D.J. Yamaguchi;Suzanne Manning

  • Colon Carcinoma Cell Growth Is Associated with Prostaglandin E2/EP4 Receptor-evoked ERK Activation

    Ambra Pozzi;Xuexian Yan;Ines Macias-Perez;Shouzuo Wei

  • Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel

    Kiyoshi Nakagawa;Vijaykumar R. Holla;Yuan Wei;Wen-Hui Wang

  • EET signaling in cancer

    Dipak Panigrahy;Emily R. Greene;Ambra Pozzi;Dao Wen Wang

  • PPAR-γ agonist protects podocytes from injury

    T. Kanjanabuch;L.-J. Ma;J. Chen;A. Pozzi

  • Transforming Growth Factor β Induces Clustering of HER2 and Integrins by Activating Src-Focal Adhesion Kinase and Receptor Association to the Cytoskeleton

    Shizhen Emily Wang;Bin Xiang;Roy Zent;Vito Quaranta

Frequent Co-Authors

Roy Zent
Roy Zent Vanderbilt University Medical Center
Raymond C. Harris
Raymond C. Harris Vanderbilt University Medical Center
Billy G. Hudson
Billy G. Hudson Vanderbilt University Medical Center
Reinhard Fässler
Reinhard Fässler Max Planck Society
Charles R. Sanders
Charles R. Sanders Vanderbilt University
David H. Wasserman
David H. Wasserman Vanderbilt University
Timothy S. Blackwell
Timothy S. Blackwell University of Michigan–Ann Arbor
Vito Quaranta
Vito Quaranta Vanderbilt University
Jorge H. Capdevila
Jorge H. Capdevila Vanderbilt University
Agnes B. Fogo
Agnes B. Fogo Vanderbilt University Medical Center

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