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Reinhard Fässler

Reinhard Fässler

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Biology and Biochemistry
Germany
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
143
Citations
65191
World Ranking
241
National Ranking
17

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2025 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2023 - Research.com Biology and Biochemistry in Germany Leader Award

Overview

Reinhard Fässler is affiliated with the Max Planck Society in Germany and has a research focus spanning biochemistry, genetics, and molecular biology, as well as medicine. Their work prominently intersects the fields of molecular biology, immunology and allergy, cell biology, hematology, and immunology.

The scientist's research topics cover a range of areas including cell adhesion molecules, cellular mechanics and interactions, cellular transport and secretion, biochemical and structural characterization, lipid membrane structure and behavior, force microscopy techniques and applications, and platelet disorders and treatments.

Frequent coauthors associated with Reinhard Fässler include Jonas Aretz, Ralph T. Böttcher, Nico Strohmeyer, Peter W. Krenn, and Mercedes Costell. Their collaborative efforts have resulted in multiple publications across several scientific venues.

  • Nature Communications
  • The Journal of Cell Biology
  • Journal of Cell Science
  • Biophysical Journal
  • Proceedings of the National Academy of Sciences

Recent significant publications by Fässler's team demonstrate a focus on cellular adhesion, integrins, and tissue repair mechanisms:

  • Neutrophils direct preexisting matrix to initiate repair in damaged tissues, 2022, Nature Immunology
  • Molecular motion and tridimensional nanoscale localization of kindlin control integrin activation in focal adhesions, 2021, Nature Communications
  • Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure, 2020, Developmental Cell
  • mTORC1 activity is supported by spatial association with focal adhesions, 2021, The Journal of Cell Biology
  • Quantitative single-protein imaging reveals molecular complex formation of integrin, talin, and kindlin during cell adhesion, 2021, Nature Communications

Best Publications

  • Rapid leukocyte migration by integrin-independent flowing and squeezing

    Tim Lämmermann;Bernhard L. Bader;Susan J. Monkley;Tim Worbs

  • Consequences of lack of beta 1 integrin gene expression in mice.

    R Fässler;M Meyer

  • ILK, PINCH and parvin: the tIPP of integrin signalling.

    Kyle R Legate;Eloi Montañez;Oliver Kudlacek;Reinhard Fässler

  • Genetic and cell biological analysis of integrin outside-in signaling.

    Kyle R. Legate;Sara A. Wickström;Reinhard Fässler

  • The Tail of Integrins, Talin, and Kindlins

    Markus Moser;Kyle R. Legate;Roy Zent;Reinhard Fässler

  • Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene

    Alison J. Coffey;Robert A. Brooksbank;Oliver Brandau;Toshitaka Oohashi

  • Integrin-mediated mechanotransduction.

    Zhiqi Sun;Shengzhen S. Guo;Reinhard Fässler

  • SILAC Mouse for Quantitative Proteomics Uncovers Kindlin-3 as an Essential Factor for Red Blood Cell Function

    Marcus Krüger;Markus Moser;Siegfried Ussar;Ingo Thievessen

  • Kindlin-3 is essential for integrin activation and platelet aggregation

    Markus Moser;Bernhard Nieswandt;Siegfried Ussar;Miroslava Pozgajova

  • Perlecan Maintains the Integrity of Cartilage and Some Basement Membranes

    Mercedes Costell;Erika Gustafsson;Attila Aszódi;Matthias Mörgelin

  • The integrin adhesome: from genes and proteins to human disease.

    Sabina E. Winograd-Katz;Reinhard Fässler;Benjamin Geiger;Kyle R. Legate

  • The integrin-actin connection, an eternal love affair

    Cord Brakebusch;Reinhard Fässler

  • The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation.

    Ganka Nikolova;Normund Jabs;Irena Konstantinova;Anna Domogatskaya

  • Glycoprotein VI but not α2β1 integrin is essential for platelet interaction with collagen

    Bernhard Nieswandt;Cord Brakebusch;Wolfgang Bergmeier;Valerie Schulte

  • DIFFERENTIAL REGULATION OF PRO-INFLAMMATORY CYTOKINES DURING WOUND HEALING IN NORMAL AND GLUCOCORTICOID-TREATED MICE

    Griseldis Hübner;Maria Brauchle;Hans Smola;Marianne Madlener

  • Defective smooth muscle regulation in cGMP kinase I‐deficient mice

    Alexander Pfeifer;Peter Klatt;Steffen Massberg;Lars Ny

  • Absence of integrin alpha 7 causes a novel form of muscular dystrophy.

    Mayer U;Saher G;Fässler R;Bornemann A

  • Negative Regulation of Fibroblast Motility by Ena/VASP Proteins

    James E Bear;Joseph J Loureiro;Irina Libova;Reinhard Fässler

  • Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-κB signaling

    Ramin Massoumi;Katarzyna Chmielarska;Katharina Hennecke;Alexander Pfeifer

  • Fibromodulin-null mice have abnormal collagen fibrils, tissue organization, and altered lumican deposition in tendon.

    Liz Svensson;Attila Aszódi;Finn P. Reinholt;Reinhard Fässler

Frequent Co-Authors

Markus Moser
Markus Moser Technical University of Munich
Cord Brakebusch
Cord Brakebusch University of Copenhagen
Roy Zent
Roy Zent Vanderbilt University Medical Center
Attila Aszódi
Attila Aszódi Ludwig-Maximilians-Universität München
Ambra Pozzi
Ambra Pozzi Vanderbilt University Medical Center
Alexander Pfeifer
Alexander Pfeifer University of Bonn
Matthias Mann
Matthias Mann Max Planck Institute of Biochemistry
Joachim P. Spatz
Joachim P. Spatz Max Planck Society
Leena Bruckner-Tuderman
Leena Bruckner-Tuderman University of Freiburg
Markus Sperandio
Markus Sperandio Ludwig-Maximilians-Universität München

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