Gerhard Wiche performs integrative study on Cytoskeleton and Actin in his works. In his research, he undertakes multidisciplinary study on Actin and Plectin. His multidisciplinary approach integrates Plectin and Vimentin in his work. In most of his Vimentin studies, his work intersects topics such as Immunology. His study brings together the fields of Neurofilament and Immunology. He applies his multidisciplinary studies on Neurofilament and Keratin in his research. His multidisciplinary approach integrates Keratin and Protein filament in his work. His multidisciplinary approach integrates Protein filament and Cytoskeleton in his work. In his works, he conducts interdisciplinary research on Intermediate filament and Epidermolysis bullosa simplex.
In general Electron microscope, his work in Optics is often linked to Biophysics linking many areas of study. As part of his studies on Optics, Gerhard Wiche frequently links adjacent subjects like Electron microscope. In his works, he conducts interdisciplinary research on Biophysics and Genetics. His Gel electrophoresis research extends to the thematically linked field of Genetics. Gerhard Wiche combines Cell biology and Neuroscience in his research. Borrowing concepts from Cell biology, he weaves in ideas under Neuroscience. As part of his studies on Cell, he often connects relevant areas like Intermediate Filament Protein. His study connects Cytoskeleton and Intermediate Filament Protein. Gerhard Wiche combines Cytoskeleton and Gene in his research.
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Accumulation of abnormally phosphorylated τ precedes the formation of neurofibrillary tangles in Alzheimer's disease
C. Bancher;C. Brunner;H. Lassmann;H. Budka.
Brain Research (1989)
Role of Plectin in Cytoskeleton Organization and Dynamics
Journal of Cell Science (1998)
Plectin deficiency results in muscular dystrophy with epidermolysis bullosa
F.J.D. Smith;R.A.J. Eady;I.M. Leigh;J.R. McMillan.
Nature Genetics (1996)
Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture
Kerstin Andrä;Hans Lassmann;Reginald Bittner;Sigrid Shorny.
Genes & Development (1997)
Defective Expression of Plectin/HD1 in Epidermolysis Bullosa Simplex with Muscular Dystrophy
Yannick Gache;Stéphane Chavanas;Jean Philippe Lacour;Gerhard Wiche.
Journal of Clinical Investigation (1996)
Not just scaffolding: plectin regulates actin dynamics in cultured cells
Kerstin Andrä;Branislav Nikolic;Markus Stöcher;Detlev Drenckhahn.
Genes & Development (1998)
Linking Integrin α6β4-based Cell Adhesion to the Intermediate Filament Cytoskeleton: Direct Interaction between the β4 Subunit and Plectin at Multiple Molecular Sites
Günther A. Rezniczek;José M. de Pereda;Siegfried Reipert;Gerhard Wiche.
Journal of Cell Biology (1998)
MAP1B is required for axon guidance and Is involved in the development of the central and peripheral nervous system.
Arabella Meixner;Silke Haverkamp;Heinz Wässle;Susanne Führer.
Journal of Cell Biology (2000)
Basic amino acid residue cluster within nuclear targeting sequence motif is essential for cytoplasmic plectin-vimentin network junctions
B Nikolic;E Mac Nulty;B Mir;G Wiche.
Journal of Cell Biology (1996)
Cloning and sequencing of rat plectin indicates a 466-kD polypeptide chain with a three-domain structure based on a central alpha-helical coiled coil.
G Wiche;B Becker;K Luber;G Weitzer.
Journal of Cell Biology (1991)
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