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Wolfram S. Kunz

Wolfram S. Kunz

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
20780
World Ranking
4356
National Ranking
323

Overview

Wolfram S. Kunz is affiliated with the University of Bonn in Germany and has a substantial body of research focusing on biochemistry, genetics, and molecular biology, as well as medicine. Their work spans various subfields including molecular biology, genetics, psychiatry and mental health, clinical biochemistry, and neurology.

Their research topics cover a range of areas with particular emphasis on mitochondrial function and pathology, genomics and rare diseases, genetics and neurodevelopmental disorders, epilepsy research and treatment, metabolism and genetic disorders, ATP synthase and ATPases research, and genomic variations and chromosomal abnormalities.

Recent published papers include:

  • Impaired complex I repair causes recessive Leber's hereditary optic neuropathy (2021) in Journal of Clinical Investigation
  • Epilepsy subtype-specific copy number burden observed in a genome-wide study of 17,458 subjects (2020) in Brain
  • Mitochondrial Retinopathy (2021) in Ophthalmology Retina
  • Cytosolic, but not matrix, calcium is essential for adjustment of mitochondrial pyruvate supply (2020) in Journal of Biological Chemistry
  • Sub-genic intolerance, ClinVar, and the epilepsies: A whole-exome sequencing study of 29,165 individuals (2021) in The American Journal of Human Genetics

Frequent collaborators in their research include Holger Lerche, Chantal Depondt, Pasquale Striano, Roland Krause, and Gianpiero L. Cavalleri.

Common venues for publishing their work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Brain
  • The American Journal of Human Genetics
  • Nucleic Acids Research

Best Publications

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells

    Andrey V Kuznetsov;Vladimir Veksler;Vladimir Veksler;Frank N Gellerich;Valdur Saks

  • Characterization of Superoxide-producing Sites in Isolated Brain Mitochondria

    Alexei P. Kudin;Nana Yaw B. Bimpong-Buta;Stefan Vielhaber;Christian E. Elger

  • Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

    Bassel Abou-Khalil;Pauls Auce;Andreja Avbersek;Melanie Bahlo

  • Permeabilized cell and skinned fiber techniques in studies of mitochondrial function in vivo

    Valdur A. Saks;Vladimir I. Veksler;Andrei V. Kuznetsov;Laurence Kay

  • Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration.

    Suzana Gispert;Filomena Ricciardi;Alexander Kurz;Mekhman Azizov

  • Recombination of Human Mitochondrial DNA

    Yevgenya Kraytsberg;Marianne Schwartz;Timothy A. Brown;Konstantin Ebralidse

  • Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis.

    Stefan Vielhaber;Dagmar Kunz;Kirstin Winkler;Falk R. Wiedemann

  • Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis

    Falk R Wiedemann;Kirstin Winkler;Andrey V Kuznetsov;Claudius Bartels

  • Neurobehavioral Outcome Prediction After Cardiac Surgery Role of Neurobiochemical Markers of Damage to Neuronal and Glial Brain Tissue

    Manfred Herrmann;Anne D. Ebert;Imke Galazky;Michael T. Wunderlich

  • Control of mitochondrial respiration

    J.M. Tager;R.J.A Wanders;A.K. Groen;W. Kunz

  • Mitochondrial complex I deficiency in the epileptic focus of patients with temporal lobe epilepsy.

    Wolfram S. Kunz;Alexei P. Kudin;Stefan Vielhaber;T. Ingmar Blümcke

  • Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies

    Richard Anney;A. Avbersek;D. Balding;L. Baum

  • Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease

    Cornelia Kornblum;Thomas J Nicholls;Tobias B Haack;Susanne Schöler

  • Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6

    Hans-Hermann Hoepken;Suzana Gispert;Blas Morales;Oliver Wingerter

  • Impaired mitochondrial oxidative phosphorylation in skeletal muscle of the dystrophin-deficient mdx mouse

    A V Kuznetsov;K Winkler;F R Wiedemann;P von Bossanyi

  • Mitochondrial dysfunction and seizures: the neuronal energy crisis

    Gábor Zsurka;Wolfram S Kunz

  • Mitochondrial potassium channels

    Adam Szewczyk;Wieslawa Jarmuszkiewicz;Wolfram S. Kunz

  • Seizure-dependent modulation of mitochondrial oxidative phosphorylation in rat hippocampus.

    Alexei P. Kudin;Tatiana A. Kudina;Jan Seyfried;Stefan Vielhaber

  • The mechanism of neuroprotection by topiramate in an animal model of epilepsy.

    Alexei P. Kudin;Grazyna Debska-Vielhaber;Stefan Vielhaber;Christian E. Elger

Frequent Co-Authors

Christian E. Elger
Christian E. Elger University Hospital Bonn
Yvonne G. Weber
Yvonne G. Weber University of Tübingen
Federico Zara
Federico Zara University of Genoa
Pasquale Striano
Pasquale Striano University of Genoa
Thomas Sander
Thomas Sander University of Cologne
Norman Delanty
Norman Delanty Beaumont Hospital
Gianpiero L. Cavalleri
Gianpiero L. Cavalleri Royal College of Surgeons in Ireland
Chantal Depondt
Chantal Depondt Université Libre de Bruxelles
Bobby P.C. Koeleman
Bobby P.C. Koeleman Utrecht University
Anthony G Marson
Anthony G Marson University of Liverpool

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