Gerald Brosch

Overview

Best Publications

• Histone deacetylase 1 can repress transcription by binding to Sp1.

  Angelika Doetzlhofer;Hans Rotheneder;Gerda Lagger;Manfred Koranda

  511
  Citations

• Inhibition of maize histone deacetylases by HC toxin, the host-selective toxin of Cochliobolus carbonum.

  Gerald Brosch;Richard Ransom;Thomas Lechner;Jonathan D. Walton

  289
  Citations

• Identification of Maize Histone Deacetylase HD2 as an Acidic Nucleolar Phosphoprotein

  Alexandra Lusser;Gerald Brosch;Adele Loidl;Hubertus Haas

  286
  Citations

• Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas

  Keith W. Vance;Suzanne Carreira;Gerald Brosch;Colin R. Goding

  279
  Citations

• Amide analogues of trichostatin A as inhibitors of histone deacetylase and inducers of terminal cell differentiation.

  Manfred Jung;Gerald Brosch;Doris Kölle;Hans Scherf

  262
  Citations

• Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides.

  Antonello Mai;Silvio Massa;Riccardo Pezzi;Silvia Simeoni

  242
  Citations

• Histone modifications and chromatin dynamics: a focus on filamentous fungi

  Gerald Brosch;Peter Loidl;Stefan Graessle

  197
  Citations

• Target-Based Approach to Inhibitors of Histone Arginine Methyltransferases

  Astrid Spannhoff;Ralf Heinke;Ingo Bauer;Patrick Trojer

  173
  Citations

• 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-alkylamides as a new class of synthetic histone deacetylase inhibitors. 1. Design, synthesis, biological evaluation, and binding mode studies performed through three different docking procedures

  Antonello Mai;Silvio Massa;Rino Ragno;Ilaria Cerbara

  170
  Citations

• epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors.

  Antonello Mai;Donghang Cheng;Mark T. Bedford;Sergio Valente

  161
  Citations

• Biochemical methods for analysis of histone deacetylases.

  Doris Kölle;Gerald Brosch;Thomas Lechner;Alexandra Lusser

  146
  Citations

• Analogues of trichosтatin a and trapoxin B as histone deacetylase inhibitors

  Manfred Jung;Katharina Hoffmann;Gerald Brosch;Peter Loidl

  137
  Citations

• A non-isotopic assay for histone deacetylase activity

  Katharina Hoffmann;Manfred Jung;Gerald Brosch;Peter Loidl

  132
  Citations

• Small molecule inhibitors of histone arginine methyltransferases: homology modeling, molecular docking, binding mode analysis, and biological evaluations.

  Rino Ragno;Silvia Simeoni;Sabrina Castellano;Caterina Vicidomini

  127
  Citations

• 1,3,4-Oxadiazole-containing histone deacetylase inhibitors: anticancer activities in cancer cells.

  Sergio Valente;Daniela Trisciuoglio;Teresa De Luca;Angela Nebbioso

  126
  Citations

• 3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors.

  Silvio Massa;Antonello Mai;Gianluca Sbardella;Monica Esposito

  126
  Citations

• Sds3 (Suppressor of Defective Silencing 3) Is an Integral Component of the Yeast Sin3·Rpd3 Histone Deacetylase Complex and Is Required for Histone Deacetylase Activity *

  Thomas Lechner;Michael J. Carrozza;Yaxin Yu;Patrick A. Grant

  121
  Citations

• Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans.

  Antonello Mai;Dante Rotili;Silvio Massa;Gerald Brosch

  118
  Citations

• A novel arginine methyltransferase inhibitor with cellular activity.

  Astrid Spannhoff;Rospita Machmur;Ralf Heinke;Patrick Trojer

  115
  Citations

• Histone deacetylase. A key enzyme for the binding of regulatory proteins to chromatin.

  Gerardo López-Rodas;Gerald Brosch;Elena I. Georgieva;Elena I. Georgieva;Ramón Sendra;Ramón Sendra

  94
  Citations