World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
75
Citations
17052
World Ranking
1206
National Ranking
93

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Colin R. Goding is affiliated with the University of Oxford in the United Kingdom. Their research spans multiple fields with a strong emphasis on Biochemistry, Genetics and Molecular Biology, alongside Medicine. Within these broad areas, their work focuses notably on Molecular Biology, Oncology, Immunology, Cancer Research, and Cell Biology.

The scientist has contributed to a range of topics, including:

  • Melanin and skin pigmentation
  • Genomics and Chromatin Dynamics
  • Melanoma and MAPK Pathways
  • Cancer, Hypoxia, and Metabolism
  • Protein Degradation and Inhibitors
  • CRISPR and Genetic Engineering
  • Autophagy in Disease and Therapy

Their recent published papers demonstrate a focus on cancer biology, molecular mechanisms of drug tolerance, and melanoma malignancy. Selected papers include:

  • Sublethal cytochrome c release generates drug-tolerant persister cells, 2022, Cell
  • The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression, 2020, Oncogene
  • The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2, 2023, Cell Reports
  • MC1R Functions, Expression, and Implications for Targeted Therapy, 2021, Journal of Investigative Dermatology
  • Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution, 2020, Molecular Cell

Frequent co-authors collaborating with Goding include:

  • Pakavarin Louphrasitthiphol
  • Jagat Chauhan
  • Jean-Philippe Lambert
  • Laura Mosteo
  • José Manuel García-Martínez

The scientist publishes regularly in several venues, with the most frequent including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Investigative Dermatology
  • Pigment Cell & Melanoma Research
  • Nature Communications
  • Cell

Among the distinctions they have received is membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage

    Colin R. Goding

  • Melanocyte-specific expression of the human tyrosinase promoter: activation by the microphthalmia gene product and role of the initiator.

    N J Bentley;T Eisen;C R Goding

  • Cancer stem cells versus phenotype-switching in melanoma.

    Keith S. Hoek;Colin R. Goding

  • Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation

    P. O'Hare;C.R. Goding

  • Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression

    Suzanne Carreira;Jane Goodall;Isil Aksan;S. Anna La Rocca

  • MITF—the first 25 years

    Colin R. Goding;Heinz Arnheiter

  • Melanoma plasticity and phenotypic diversity: therapeutic barriers and opportunities.

    Florian Rambow;Jean-Christophe Marine;Jean-Christophe Marine;Colin R. Goding

  • Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas

    Keith W. Vance;Suzanne Carreira;Gerald Brosch;Colin R. Goding

  • Targeting the Microphthalmia Basic Helix-Loop-Helix-Leucine Zipper Transcription Factor to a Subset of E-Box Elements In Vitro and In Vivo

    I. Aksan;C. R. Goding

  • Mutational analysis of the adenovirus E1a gene: the role of transcriptional regulation in transformation.

    J. F. Schneider;F. Fisher;C. R. Goding;N. C. Jones

  • Afamelanotide for Erythropoietic Protoporphyria

    J. G. Langendonk;M. Balwani;Karl Anderson;H. L. Bonkovsky

  • Single amino acid substitutions alter helix-loop-helix protein specificity for bases flanking the core CANNTG motif.

    F Fisher;C R Goding

  • The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression.

    Marie-Dominique Galibert;Suzanne Carreira;Colin R. Goding

  • The Transcription Network Regulating Melanocyte Development and Melanoma

    Keith W Vance;Colin R Goding

  • Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia- Associated Transcription Factor-Negative Melanoma Cells

    Jane Goodall;Suzanne Carreira;Laurence Denat;Dominique Kobi

  • Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination

    Sophie Pinner;Peter Jordan;Kirsty Sharrock;Laura Bazley

  • CBP/p300 as a co-factor for the Microphthalmia transcription factor

    S Sato;K Roberts;G Gambino;A Cook

  • Direct Regulation of the Microphthalmia Promoter by Sox10 Links Waardenburg-Shah Syndrome (WS4)-associated Hypopigmentation and Deafness to WS2

    Melanie Lee;Jane Goodall;Carole Verastegui;Robert Ballotti

  • Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.

    Paola Falletta;Luis Sanchez-del-Campo;Jagat Chauhan;Maike Effern

  • The Microphthalmia-Associated Transcription Factor Mitf Interacts with β-Catenin To Determine Target Gene Expression

    Alexander Schepsky;Katja Bruser;Gunnar J. Gunnarsson;Jane Goodall

Frequent Co-Authors

Lionel Larue
Lionel Larue University of Paris-Saclay
Eirikur Steingrimsson
Eirikur Steingrimsson University of Iceland
Panagis Filippakopoulos
Panagis Filippakopoulos Structural Genomics Consortium
Irwin Davidson
Irwin Davidson Institute of Genetics and Molecular and Cellular Biology
Wenyi Wei
Wenyi Wei Beth Israel Deaconess Medical Center
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Göran Jönsson
Göran Jönsson Lund University
Xin Lu
Xin Lu University of Oxford
Dorothy C. Bennett
Dorothy C. Bennett St George's, University of London
Ze'ev Ronai
Ze'ev Ronai Cedars-Sinai Medical Center

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