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Molecular Biology

D-Index
105
Citations
34592
World Ranking
451
National Ranking
253

Overview

Ze'ev Ronai is primarily affiliated with the Sanford Burnham Prebys Medical Discovery Institute in the United States. Their research spans key areas of biochemistry, genetics, and molecular biology, with a significant focus on medicine. Their publication record highlights contributions predominantly in molecular biology, oncology, immunology, cancer research, and hematology.

The main research topics covered across their work include:

  • Epigenetics and DNA Methylation
  • Ubiquitin and Proteasome Pathways
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Protein Degradation and Inhibitors
  • Melanoma and MAPK Pathways
  • Immune Cell Function and Interaction

Ronai has co-authored extensively with several researchers, with the most frequent collaborators being Hyungsoo Kim, Yongmei Feng, Rabi Murad, Eytan Ruppin, and Joo Sang Lee.

Their recent publications reflect a focus on cancer biology and immunology, with notable papers including:

  • "Melanoma models for the next generation of therapies" (2021) published in Cancer Cell
  • "PRMT5 function and targeting in cancer" (2020) published in Cell Stress
  • "PRMT5 control of cGAS/STING and NLRC5 pathways defines melanoma response to antitumor immunity" (2020) published in Science Translational Medicine
  • "Prebiotic-Induced Anti-tumor Immunity Attenuates Tumor Growth" (2020) published in Cell Reports
  • "Synthetic lethality-mediated precision oncology via the tumor transcriptome" (2021) published in Cell

Ronai's research has appeared repeatedly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Nature Communications, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, and Cancer Cell, indicating their engagement with a variety of peer-reviewed platforms that cover biomedical science and cancer research.

Best Publications

  • Regulation of JNK signaling by GSTp

    Victor Adler;Zhimin Yin;Serge Y. Fuchs;Miriam Benezra

  • UPR, autophagy, and mitochondria crosstalk underlies the ER stress response

    Daniela Senft;Ze’ev A. Ronai

  • ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.

    Ruth Maya;Moshe Balass;Seong-Tae Kim;Dganit Shkedy

  • Role of redox potential and reactive oxygen species in stress signaling.

    Victor Adler;Zhimin Yin;Kenneth D Tew;Ze'ev Ronai

  • MEKK1/JNK signaling stabilizes and activates p53.

    Serge Y. Fuchs;Victor Adler;Matthew R. Pincus;Ze’ev Ronai

  • The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

    Paola Zacchi;Paola Zacchi;Monica Gostissa;Takafumi Uchida;Clio Salvagno;Clio Salvagno

  • Siah2 Regulates Stability of Prolyl-Hydroxylases, Controls HIF1α Abundance, and Modulates Physiological Responses to Hypoxia

    Koh Nakayama;Ian J Frew;Mette Hagensen;Marianne Gerberg Skals

  • Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation

    Hui Xiong;Danling Wang;Linan Chen;Yeun Su Choo

  • JNK targets p53 ubiquitination and degradation in nonstressed cells

    Serge Y. Fuchs;Victor Adler;Thomas Buschmann;Zhimin Yin

  • Ubiquitin ligases in oncogenic transformation and cancer therapy

    Daniela Senft;Jianfei Qi;Ze'ev A. Ronai;Ze'ev A. Ronai

  • Cellular Thiols and Reactive Oxygen Species in Drug-Induced Apoptosis

    Warren Davis;Ze'ev Ronai;Kenneth D. Tew

  • Recruitment of a ROC1–CUL1 Ubiquitin Ligase by Skp1 and HOS to Catalyze the Ubiquitination of IκBα

    Peilin Tan;Serge Y. Fuchs;Angus Chen;Kenneth Wu

  • Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.

    Thomas Buschmann;Olga Potapova;Anat Bar-Shira;Vladimir N. Ivanov

  • BRAF Oncogenic Mutations Correlate with Progression rather than Initiation of Human Melanoma

    Jianli Dong;Robert G. Phelps;Rui Qiao;Shen Yao

  • Glutathione S-transferase P1–1 (GSTP1–1) Inhibits c-Jun N-terminal Kinase (JNK1) Signaling through Interaction with the C Terminus

    Tieli Wang;Pinar Arifoglu;Ze'ev Ronai;Kenneth D. Tew

  • Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect.

    David A. Scott;Adam D. Richardson;Fabian V. Filipp;Christine A. Knutzen

  • p53–Mdm2—the affair that never ends

    Dania Alarcon-Vargas;Ze'ev Ronai

  • SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.

    Thomas Buschmann;Serge Y Fuchs;Chee-Gun Lee;Zhen-Qiang Pan

  • Structural Mechanism of the Bromodomain of the Coactivator CBP in p53 Transcriptional Activation

    Shiraz Mujtaba;Yan He;Lei Zeng;Sherry Yan

  • ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation

    Hasem Habelhah;Kavita Shah;Lan Huang;Antje Ostareck-Lederer

Frequent Co-Authors

David D.L. Bowtell
David D.L. Bowtell Peter MacCallum Cancer Centre
Eytan Ruppin
Eytan Ruppin National Institutes of Health
Maurizio Pellecchia
Maurizio Pellecchia University of California, Riverside
Marcus Bosenberg
Marcus Bosenberg Yale University
Harriet M. Kluger
Harriet M. Kluger Yale University
Meenhard Herlyn
Meenhard Herlyn The Wistar Institute
Ivan Topisirovic
Ivan Topisirovic McGill University
Kevin K. Brown
Kevin K. Brown National Jewish Health
Andrei L. Osterman
Andrei L. Osterman Discovery Institute
Kenneth D. Tew
Kenneth D. Tew Medical University of South Carolina

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