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Giannino Del Sal

Giannino Del Sal

D-Index & Metrics

Molecular Biology

D-Index
66
Citations
19117
World Ranking
1610
National Ranking
32

Overview

Giannino Del Sal is affiliated with the University of Trieste in Italy. Their research predominantly spans the fields of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Oncology, Cell Biology, Cancer Research, and Immunology.

The scientist's work covers several main topics, including:

  • Cancer Cells and Metastasis
  • Hippo pathway signaling and YAP/TAZ
  • Epigenetics and DNA Methylation
  • Cancer-related Molecular Pathways
  • Nuclear Structure and Function
  • MicroRNA in disease regulation
  • RNA Research and Splicing

Del Sal has published numerous papers in well-known venues such as Nature Communications, Cell Death and Differentiation, Experimental & Molecular Medicine, Cancers, and Cell Reports. Frequent publication venues with multiple contributions include:

  • Nature Communications
  • Cell Death and Differentiation
  • Experimental & Molecular Medicine
  • Cancers
  • Cell Reports

Notable recent papers include:

  • "Apoptotic cell death in disease-Current understanding of the NCCD 2023," published in 2023 in Cell Death and Differentiation
  • "Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome," published in 2020 in Nature Communications
  • "Breast Cancer Organoids Model Patient-Specific Response to Drug Treatment," published in 2020 in Cancers
  • "The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress," published in 2021 in Cell Reports
  • "Mutant p53 sustains serine-glycine synthesis and essential amino acids intake promoting breast cancer growth," published in 2023 in Nature Communications

Throughout their career, Del Sal has collaborated frequently with several coauthors, among them:

  • Claudio Tripodo
  • Fiamma Mantovani
  • Valeria Cancila
  • Silvano Piazza
  • Silvio Bicciato

Their research contributions emphasize molecular pathways involved in cancer progression, nuclear structure and function, and mechanisms underlying disease regulation at the molecular level.

Best Publications

  • Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

    Michele Pagano;Sun W. Tam;Anne M. Theodoras;Peggy Beer-Romero

  • Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis

    Gabriella D'Orazi;Barbara Cecchinelli;Tiziana Bruno;Isabella Manni

  • Metabolic control of YAP and TAZ by the mevalonate pathway

    Giovanni Sorrentino;Naomi Ruggeri;Valeria Specchia;Michelangelo Cordenonsi

  • Activation of p53 by conjugation to the ubiquitin‐like protein SUMO‐1

    Monica Gostissa;Arnd Hengstermann;Valentina Fogal;Peter Sandy

  • Mutant p53 as a guardian of the cancer cell

    Fiamma Mantovani;Fiamma Mantovani;Licio Collavin;Licio Collavin;Giannino Del Sal;Giannino Del Sal

  • Dynamic landscape and regulation of RNA editing in mammals

    Meng How Tan;Qin Li;Raghuvaran Shanmugam;Robert Piskol

  • Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc.

    Paolo Pinton;Alessandro Rimessi;Saverio Marchi;Francesca Orsini

  • The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

    Paola Zacchi;Paola Zacchi;Monica Gostissa;Takafumi Uchida;Clio Salvagno;Clio Salvagno

  • Regulation of p53 activity in nuclear bodies by a specific PML isoform

    Valentina Fogal;Monica Gostissa;Peter Sandy;Paola Zacchi

  • The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage.

    Sabrina Strano;Olimpia Monti;Natalia Pediconi;Alessia Baccarini

  • A one-tube plasmid DNA mini-preparation suitable for sequencing

    Giannino Del Sal;Guidalberto Manfioletti;Claudio Schneider

  • The rebel angel: mutant p53 as the driving oncogene in breast cancer

    Dawid Walerych;Marco Napoli;Marco Napoli;Licio Collavin;Giannino Del Sal

  • A Pin1/mutant p53 axis promotes aggressiveness in breast cancer.

    Javier E. Girardini;Javier E. Girardini;Marco Napoli;Marco Napoli;Silvano Piazza;Alessandra Rustighi;Alessandra Rustighi

  • iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53.

    Daniele Bergamaschi;Yardena Samuels;Yardena Samuels;Yardena Samuels;Alexandra Sullivan;Marketa Zvelebil

  • p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner.

    Carlotta Giorgi;Massimo Bonora;Giovanni Sorrentino;Sonia Missiroli

  • Physical interaction with human tumor-derived p53 mutants inhibits p63 activities

    Sabrina Strano;Giulia Fontemaggi;Antonio Costanzo;Maria Giulia Rizzo

  • Direct p53 Transcriptional Repression: In Vivo Analysis of CCAAT-Containing G2/M Promoters

    Carol Imbriano;Aymone Gurtner;Fabienne Cocchiarella;Silvia Di Agostino

  • Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.

    Dawid Walerych;Kamil Lisek;Kamil Lisek;Roberta Sommaggio;Silvano Piazza

  • BRD7 is a candidate tumour suppressor gene required for p53 function.

    Jarno Drost;Fiamma Mantovani;Fiamma Mantovani;Francesca Tocco;Francesca Tocco;Ran Elkon

  • Pin1 Links the Activities of c-Abl and p300 in Regulating p73 Function

    Fiamma Mantovani;Fiamma Mantovani;Silvano Piazza;Monica Gostissa;Sabrina Strano

Frequent Co-Authors

Claudio Schneider
Claudio Schneider University of Udine
Silvio Bicciato
Silvio Bicciato University of Modena and Reggio Emilia
Giovanni Blandino
Giovanni Blandino McMaster University
Stefano Gustincich
Stefano Gustincich Italian Institute of Technology
Sabrina Strano
Sabrina Strano McMaster University
Claudio Brancolini
Claudio Brancolini University of Udine
Reuven Agami
Reuven Agami Antoni van Leeuwenhoek Hospital
Guidalberto Manfioletti
Guidalberto Manfioletti University of Trieste
Roberto Mantovani
Roberto Mantovani University of Milan

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