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Massimo Levrero

Massimo Levrero

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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
29397
World Ranking
3282
National Ranking
78

Medicine

D-Index
83
Citations
29280
World Ranking
15485
National Ranking
502

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Massimo Levrero is affiliated with Inserm in France and specializes primarily in the field of Medicine, with a strong focus on Epidemiology, Hepatology, Molecular Biology, Immunology, and Oncology. Their body of work spans various subfields, emphasizing clinical and molecular aspects of liver diseases and viral infections.

The main topics of their research include:

  • Hepatitis B Virus Studies
  • Liver Disease Diagnosis and Treatment
  • Hepatitis C virus research
  • Hepatitis Viruses Studies and Epidemiology
  • Epigenetics and DNA Methylation
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Immunotherapy and Immune Responses

Massimo Levrero has published extensively, with key contributions appearing in prominent journals. Frequent publication venues for their work include:

  • Journal of Hepatology (27 publications)
  • Gut (5 publications)
  • JHEP Reports (5 publications)
  • Digestive and Liver Disease (4 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)

Selected recent papers authored or co-authored by Levrero encompass:

  • "Hepatitis B protein HBx binds the DLEU2 lncRNA to sustain cccDNA and host cancer-related gene transcription," 2020, Gut
  • "The scientific basis of combination therapy for chronic hepatitis B functional cure," 2023, Nature Reviews Gastroenterology & Hepatology
  • "Structural Variations of Vaginal and Endometrial Microbiota: Hints on Female Infertility," 2020, Frontiers in Cellular and Infection Microbiology
  • "Targeting p53 and histone methyltransferases restores exhausted CD8+ T cells in HCV infection," 2020, Nature Communications
  • "Quantification of the hepatitis B virus cccDNA: evidence-based guidelines for monitoring the key obstacle of HBV cure," 2023, Gut

Collaboration constitutes a significant aspect of Levrero's research activities. Frequent co-authors include Fabien Zoulim, Marie-Laure Plissonnier, Barbara Testoni, Francesca Guerrieri, and Marintha Heil, demonstrating active participation in multidisciplinary teams focused on liver disease and virology research.

Best Publications

  • The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

    JianGen Gong;Antonio Costanzo;Hong-Qiong Yang;Gerry Melino

  • Statements from the Taormina expert meeting on occult hepatitis B virus infection.

    Giovanni Raimondo;Jean Pierre Allain;Maurizia R. Brunetto;Marie Annick Buendia

  • Mechanisms of HBV-induced hepatocellular carcinoma

    Massimo Levrero;Massimo Levrero;Massimo Levrero;Jessica Zucman-Rossi

  • The Human Toll Signaling Pathway: Divergence of Nuclear Factor κB and JNK/SAPK Activation Upstream of Tumor Necrosis Factor Receptor–associated Factor 6 (TRAF6)

    Marta Muzio;Gioacchino Natoli;Simona Saccani;Massimo Levrero

  • The p53/p63/p73 family of transcription factors: overlapping and distinct functions

    M. Levrero;V. De Laurenzi;A. Costanzo;J. Gong

  • Control of cccDNA function in hepatitis B virus infection

    Massimo Levrero;Teresa Pollicino;Jorg Petersen;Laura Belloni

  • Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

    Antonio Bertoletti;Alessandro Sette;Francis V. Chisari;Amalia Penna

  • IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome

    Laura Belloni;Lena Allweiss;Francesca Guerrieri;Natalia Pediconi

  • Hepatitis B Virus Replication Is Regulated by the Acetylation Status of Hepatitis B Virus cccDNA-Bound H3 and H4 Histones

    Teresa Pollicino;Laura Belloni;Giuseppina Raffa;Natalia Pediconi

  • Activation of SAPK/JNK by TNF Receptor 1 Through a Noncytotoxic TRAF2-Dependent Pathway

    Gioacchino Natoli;Antonio Costanzo;Angelo Ianni;Dennis J. Templeton

  • Viral hepatitis and liver cancer: the case of hepatitis C.

    Massimo Levrero

  • Two new p73 splice variants, gamma and delta, with different transcriptional activity.

    Vincenzo De Laurenzi;Antonio Costanzo;Daniela Barcaroli;Alessandro Terrinoni

  • Evaluation of the transfer and expression in mice of an enzyme-encoding gene using a human adenovirus vector.

    Leslie D. Stratford-Perricaudet;Massimo Levrero;Jean-François Chasse;Michel Perricaudet

  • Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection

    Julie Lucifora;Silke Arzberger;David Durantel;David Durantel;David Durantel;Laura Belloni;Laura Belloni

  • Update of the statements on biology and clinical impact of occult hepatitis B virus infection

    Giovanni Raimondo;Stephen Locarnini;Teresa Pollicino;Massimo Levrero

  • Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function

    Laura Belloni;Teresa Pollicino;Francesca De Nicola;Francesca Guerrieri

  • Differential roles of p300 and PCAF acetyltransferases in muscle differentiation

    Pier Lorenzo Puri;Pier Lorenzo Puri;Vittorio Sartorelli;Vittorio Sartorelli;Xiang Jiao Yang;Yasuo Hamamori

  • Regulation of the p300 HAT domain via a novel activation loop

    Paul R Thompson;Paul R Thompson;Dongxia Wang;Ling Wang;Marcella Fulco

  • A global scientific strategy to cure hepatitis B

    Peter A Revill;Francis V Chisari;Joan M Block;Maura Dandri

  • The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage.

    Sabrina Strano;Olimpia Monti;Natalia Pediconi;Alessia Baccarini

Frequent Co-Authors

Gioacchino Natoli
Gioacchino Natoli European Institute of Oncology
Vincenzo Barnaba
Vincenzo Barnaba Sapienza University of Rome
Giovanni Blandino
Giovanni Blandino McMaster University
Antonio Craxì
Antonio Craxì University of Palermo
Carlo Ferrari
Carlo Ferrari University of Parma
Pier Lorenzo Puri
Pier Lorenzo Puri Discovery Institute
Pietro Lampertico
Pietro Lampertico University of Milan
Alfredo Alberti
Alfredo Alberti University of Padua

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