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Biology and Biochemistry

D-Index
54
Citations
13312
World Ranking
15467
National Ranking
1095

Overview

Koichi Watashi is affiliated with the National Institute of Infectious Diseases in Japan. Their research primarily focuses on infectious diseases, with significant contributions in medicine and molecular biology.

The main fields of study covered by their work include:

  • Medicine

The subfields of study they frequently work in are:

  • Epidemiology
  • Infectious Diseases
  • Hepatology
  • Molecular Biology
  • Virology

The scientist's research topics encompass:

  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • SARS-CoV-2 and COVID-19 Research
  • Liver Disease Diagnosis and Treatment
  • COVID-19 Clinical Research Studies
  • Bacteriophages and microbial interactions
  • Poxvirus research and outbreaks

Frequent co-authors working alongside Koichi Watashi include:

  • Takaji Wakita
  • Masamichi Muramatsu
  • Shingo Iwami
  • Hirofumi Ohashi
  • Yoshimasa Takahashi

The scientist has published extensively in several venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Virology
  • Antiviral Research
  • Nature Communications
  • Scientific Reports

Some recent papers by Koichi Watashi include:

  • "Hepatitis B virus biology and life cycle," 2020, Antiviral Research
  • "Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatment," 2021, iScience
  • "A quantitative model used to compare within-host SARS-CoV-2, MERS-CoV, and SARS-CoV dynamics provides insights into the pathogenesis and treatment of SARS-CoV-2," 2021, PLoS Biology
  • "Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells," 2021, Cell Reports
  • "Structural insights into the HBV receptor and bile acid transporter NTCP," 2022, Nature

Best Publications

  • The lipid droplet is an important organelle for hepatitis C virus production.

    Yusuke Miyanari;Kimie Atsuzawa;Nobuteru Usuda;Koichi Watashi

  • Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes.

    Koichi Watashi;Makoto Hijikata;Masahiro Hosaka;Masashi Yamaji

  • Cyclophilin B Is a Functional Regulator of Hepatitis C Virus RNA Polymerase

    Koichi Watashi;Naoto Ishii;Makoto Hijikata;Daisuke Inoue

  • A global scientific strategy to cure hepatitis B

    Peter A Revill;Francis V Chisari;Joan M Block;Maura Dandri

  • The RNA sensor RIG-I dually functions as an innate sensor and direct antiviral factor for hepatitis B virus

    Seiichi Sato;Kai Li;Takeshi Kameyama;Takaya Hayashi

  • Gut Microbiota Promotes Obesity-Associated Liver Cancer through PGE2-Mediated Suppression of Antitumor Immunity.

    Tze Mun Loo;Fumitaka Kamachi;Yoshihiro Watanabe;Shin Yoshimoto

  • Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP)

    Koichi Watashi;Ann Sluder;Takuji Daito;Takuji Daito;Satoko Matsunaga

  • Pyrosequencing of small non-coding RNAs in HIV-1 infected cells: evidence for the processing of a viral-cellular double-stranded RNA hybrid

    Man Lung Yeung;Yamina Bennasser;Koichi Watashi;Shu-Yun Le

  • Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP.

    Masashi Iwamoto;Koichi Watashi;Koichi Watashi;Senko Tsukuda;Hussein Hassan Aly

  • Epidermal growth factor receptor is a host-entry cofactor triggering hepatitis B virus internalization

    Masashi Iwamoto;Masashi Iwamoto;Wakana Saso;Wakana Saso;Ryuichi Sugiyama;Koji Ishii

  • Hepatitis B virus biology and life cycle.

    Senko Tsukuda;Koichi Watashi

  • Diverse Effects of Cyclosporine on Hepatitis C Virus Strain Replication

    Naoto Ishii;Koichi Watashi;Takayuki Hishiki;Kaku Goto

  • Expression of activation-induced cytidine deaminase in human hepatocytes via NF-κB signaling

    Y. Endo;H. Marusawa;K. Kinoshita;T. Morisawa

  • Evaluation of the anti-hepatitis C virus effects of cyclophilin inhibitors, cyclosporin A, and NIM811

    Kaku Goto;Koichi Watashi;Takayuki Murata;Takayuki Hishiki

  • Interleukin-1 and Tumor Necrosis Factor-α Trigger Restriction of Hepatitis B Virus Infection via a Cytidine Deaminase Activation-induced Cytidine Deaminase (AID)

    Koichi Watashi;Guoxin Liang;Masashi Iwamoto;Hiroyuki Marusawa

  • Potential anti-COVID-19 agents, Cepharanthine and Nelfinavir, and their usage for combination treatment.

    Hirofumi Ohashi;Hirofumi Ohashi;Koichi Watashi;Wakana Saso;Wakana Saso;Kaho Shionoya;Kaho Shionoya

  • NTCP and Beyond: Opening the Door to Unveil Hepatitis B Virus Entry

    Koichi Watashi;Stephan Urban;Wenhui Li;Takaji Wakita

  • Antiviral Activity of Glycyrrhizin against Hepatitis C Virus In Vitro

    Yoshihiro Matsumoto;Tomokazu Matsuura;Haruyo Aoyagi;Mami Matsuda

  • Identification of Small Molecules That Suppress MicroRNA Function and Reverse Tumorigenesis

    Koichi Watashi;Man Lung Yeung;Matthew F. Starost;Ramachandra S. Hosmane

  • Novel robust in vitro hepatitis B virus infection model using fresh human hepatocytes isolated from humanized mice.

    Yuji Ishida;Chihiro Yamasaki;Ami Yanagi;Yasumi Yoshizane

Frequent Co-Authors

Takaji Wakita
Takaji Wakita National Institute of Infectious Diseases
Masamichi Muramatsu
Masamichi Muramatsu National Institutes of Health
Hideki Aizaki
Hideki Aizaki National Institutes of Health
Yasuhito Tanaka
Yasuhito Tanaka Kumamoto University
Masashi Mizokami
Masashi Mizokami National Center For Global Health and Medicine
Tetsuro Suzuki
Tetsuro Suzuki Hamamatsu University
Camille Sureau
Camille Sureau Centre national de la recherche scientifique, CNRS
Akihide Ryo
Akihide Ryo Yokohama City University
Kazuaki Chayama
Kazuaki Chayama Hiroshima University
Tadaki Suzuki
Tadaki Suzuki National Institutes of Health

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