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Biology and Biochemistry
USA
2026
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Neuroscience
USA
2026

D-Index & Metrics

Neuroscience

D-Index
159
Citations
103379
World Ranking
113
National Ranking
74

Biology and Biochemistry

D-Index
159
Citations
103256
World Ranking
129
National Ranking
95

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2026 - Research.com Neuroscience in United States Leader Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Neuroscience in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Stuart A. Lipton is affiliated with the Scripps Research Institute in the United States. Their research spans several fields including Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience.

The scientist's work frequently appears in notable publication venues such as bioRxiv (Cold Spring Harbor Laboratory), Free Radical Biology and Medicine, Proceedings of the National Academy of Sciences, Neurotherapeutics, and Antioxidants.

Research contributions focus on a range of topics with an emphasis on Alzheimer's disease research and treatments, neuroscience and neuropharmacology research, tryptophan and brain disorders, autophagy in disease and therapy, redox biology and oxidative stress, nitric oxide and endothelin effects, and receptor mechanisms and signaling.

Key recent papers include:

  • Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation, 2021, Immunity
  • Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia, 2021, Proceedings of the National Academy of Sciences
  • Potential Therapeutic Use of the Rosemary Diterpene Carnosic Acid for Alzheimer's Disease, Parkinson's Disease, and Long-COVID through NRF2 Activation to Counteract the NLRP3 Inflammasome, 2022, Antioxidants
  • α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss, 2021, Journal of Neuroscience
  • Noncanonical transnitrosylation network contributes to synapse loss in Alzheimer's disease, 2020, Science

Frequent co-authors collaborating with Stuart A. Lipton include:

  • Tomohiro Nakamura
  • Xu Zhang
  • Dorit Trudler
  • Chang-ki Oh
  • Swagata Ghatak

Stuart A. Lipton has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2011.

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Classification of cell death: recommendations of the Nomenclature Committee on Cell Death

    G. Kroemer;G. Kroemer;G. Kroemer;L. Galluzzi;L. Galluzzi;L. Galluzzi;P. Vandenabeele;J. Abrams

  • Excitatory amino acids as a final common pathway for neurologic disorders.

    Stuart A. Lipton;Paul A. Rosenberg

  • Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

    Galluzzi L;Vitale I;Vitale I;Vitale I;Abrams Jm;Alnemri Es

  • A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

    Stuart A. Lipton;Yun-Beom Choi;Yun-Beom Choi;Zhuo-Hua Pan;Zhuo-Hua Pan;Sizheng Z. Lei;Sizheng Z. Lei

  • Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

    Emanuela Bonfoco;Dimitri Krainc;Maria Ankarcrona;Pierluigi Nicotera

  • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

    Maria Ankarcrona;Jeannette M. Dypbukt;Emanuela Bonfoco;Boris Zhivotovsky

  • Pathways to neuronal injury and apoptosis in HIV-associated dementia

    Marcus Kaul;Gwenn A. Garden;Stuart A. Lipton

  • Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades.

    Murat Digicaylioglu;Stuart A. Lipton;Stuart A. Lipton

  • S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury

    Dong-Hyung Cho;Tomohiro Nakamura;Jianguo Fang;Piotr Cieplak

  • S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death.

    Zezong Gu;Marcus Kaul;Boxu Yan;Steven J. Kridel

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • Neurotoxicity associated with dual actions of homocysteine at the N-methyl-d-aspartate receptor

    Stuart A. Lipton;Won Ki Kim;Yun Beom Choi;Shanta Kumar

  • Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond

    Stuart A. Lipton

  • S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration.

    Takashi Uehara;Tomohiro Nakamura;Dongdong Yao;Zhong Qing Shi

  • Molecular pathways to neurodegeneration

    Ella Bossy-Wetzel;Robert Schwarzenbacher;Stuart A Lipton

  • Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits

    Jon E Chatterton;Marc Awobuluyi;Louis S Premkumar;Hiroto Takahashi

  • Neurotransmitter regulation of neuronal outgrowth, plasticity and survival

    Stuart A. Lipton;Stanley B. Kater

  • Elevated Glutamate Levels in the Vitreous Body of Humans and Monkeys With Glaucoma

    Evan B. Dreyer;David Zurakowski;Robert A. Schumer;Steven M. Podos

  • Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex

    Sizheng Z. Lei;Zhuo Hua Pan;Sanjay K. Aggarwal;Huei Sheng Vincent Chen

Frequent Co-Authors

Igor Grant
Igor Grant University of California, San Diego
Howard E. Gendelman
Howard E. Gendelman University of Nebraska Medical Center
Eliezer Masliah
Eliezer Masliah National Institutes of Health
Jonathan S. Stamler
Jonathan S. Stamler Case Western Reserve University
Pierluigi Nicotera
Pierluigi Nicotera German Center for Neurodegenerative Diseases
Oliver Kepp
Oliver Kepp Institut Gustave Roussy
Ella Bossy-Wetzel
Ella Bossy-Wetzel University of Central Florida
John R. Yates
John R. Yates Scripps Research Institute
Huaxi Xu
Huaxi Xu Xiamen University
Elias Aizenman
Elias Aizenman University of Pittsburgh

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