World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
63
Citations
11797
World Ranking
3435
National Ranking
1588

Biology and Biochemistry

D-Index
63
Citations
11824
World Ranking
10402
National Ranking
4514

Overview

Elias Aizenman is affiliated with the University of Pittsburgh in the United States. Their research focuses on the interplay between trace elements and neural function, with significant contributions in neuroscience and biochemistry.

The scientist's main fields of study include Biochemistry, Genetics and Molecular Biology as well as Neuroscience. Within these areas, their subfields of expertise cover Molecular Biology, Nutrition and Dietetics, Cellular and Molecular Neuroscience, Physiology, and Health, Toxicology and Mutagenesis.

Aizenman's research spans several key topics, with work covering Trace Elements in Health, Neuroscience and Neuropharmacology Research, Ion Channel Regulation and Function, Heavy Metal Exposure and Toxicity, Alzheimer's Disease Research and Treatments, Neuroinflammation and Neurodegeneration Mechanisms, and Aluminum Toxicity and Tolerance in Plants and Animals.

They have published extensively in various scientific venues. The most frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Science Advances, Journal of Neurochemistry, Preprints.org, and Neuroscience Letters.

Recent notable papers by Aizenman encompass the following:

  • The Function and Regulation of Zinc in the Brain, 2021, Neuroscience
  • Synaptic zinc inhibition of NMDA receptors depends on the association of GluN2A with the zinc transporter ZnT1, 2020, Science Advances
  • The physiological and pathophysiological roles of copper in the nervous system, 2024, European Journal of Neuroscience
  • The Multifaceted Roles of Zinc in Neuronal Mitochondrial Dysfunction, 2021, Biomedicines
  • Targeted disruption of Kv2.1-VAPA association provides neuroprotection against ischemic stroke in mice by declustering Kv2.1 channels, 2020, Science Advances

The scientist frequently collaborates with several co-authors. These include Jenna R. Gale, Thanos Tzounopoulos, Karen A. Hartnett-Scott, Rebecca Krall, and Hila Asraf.

Best Publications

  • Selective modulation of NMDA responses by reduction and oxidation.

    Elias Aizenman;Stuart A. Lipton;Ralph H. Loring;Ralph H. Loring

  • Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex.

    Paul A. Rosenberg;Elias Aizenman;Elias Aizenman

  • Induction of neuronal apoptosis by thiol oxidation: putative role of intracellular zinc release.

    Elias Aizenman;Amy K. Stout;Karen A. Hartnett;Kirk E. Dineley

  • Caspase 3 activation is essential for neuroprotection in preconditioning.

    BethAnn McLaughlin;Karen A. Hartnett;Joseph A. Erhardt;Jeffrey J. Legos

  • The neurophysiology and pathology of brain zinc.

    Stefano L. Sensi;Pierre Paoletti;Jae-Young Koh;Elias Aizenman

  • Trapping Channel Block of NMDA-Activated Responses By Amantadine and Memantine

    Thomas A. Blanpied;Faye A. Boeckman;Elias Aizenman;Jon W. Johnson

  • Mediation of Neuronal Apoptosis by Kv2.1-Encoded Potassium Channels

    Sumon Pal;Karen A. Hartnett;Jeanne M. Nerbonne;Edwin S. Levitan

  • Oxygen free radicals regulate NMDA receptor function via a redox modulatory site.

    Elias Aizenman;Karen A. Hartnett;Ian J. Reynoldst

  • Nicotinic Antagonists Enhance Process Outgrowth by Rat Retinal Ganglion Cells in Culture

    Stuart A. Lipton;Matthew P. Frosch;Micheal D. Phillips;David L. Tauck

  • Central mammalian neurons normally resistant to glutamate toxicity are made sensitive by elevated extracellular Ca2+: toxicity is blocked by the N-methyl-D-aspartate antagonist MK-801

    Jin S. Hahn;Elias Aizenman;Stuart A. Lipton

  • Peroxynitrite-Induced Neuronal Apoptosis Is Mediated by Intracellular Zinc Release and 12-Lipoxygenase Activation

    Yumin Zhang;Hong Wang;Jianrong Li;Daniel A. Jimenez

  • p38 Activation Is Required Upstream of Potassium Current Enhancement and Caspase Cleavage in Thiol Oxidant-Induced Neuronal Apoptosis

    BethAnn McLaughlin;Sumon Pal;Minhnga P. Tran;Andrew A. Parsons

  • Nitric oxide modulates NMDA-induced increases in intracellular Ca2+ in cultured rat forebrain neurons.

    Kari R. Hoyt;Liang-Hong Tang;Elias Aizenman;Ian J. Reynolds

  • Voltage-gated potassium channels at the crossroads of neuronal function, ischemic tolerance, and neurodegeneration.

    Niyathi Hegde Shah;Elias Aizenman

  • GRIN2D Recurrent De Novo Dominant Mutation Causes a Severe Epileptic Encephalopathy Treatable with NMDA Receptor Channel Blockers

    Dong Li;Hongjie Yuan;Xilma R. Ortiz-Gonzalez;Xilma R. Ortiz-Gonzalez;Eric D. Marsh;Eric D. Marsh

  • Responses mediated by excitatory amino acid receptors in solitary retinal ganglion cells from rat.

    E Aizenman;M P Frosch;S A Lipton

  • Upregulation of KCC2 Activity by Zinc-Mediated Neurotransmission via the mZnR/GPR39 Receptor

    Ehud Chorin;Ofir Vinograd;Ilya Fleidervish;David Gilad

  • The role of intracellular zinc release in aging, oxidative stress, and Alzheimer’s disease

    Meghan C. McCord;Elias Aizenman

  • The modulation of N‐methyl‐D‐aspartate receptors by redox and alkylating reagents in rat cortical neurones in vitro.

    Lian-Hong Tang;E. Aizenman

  • Reverse Na+/Ca2+ exchange contributes to glutamate-induced intracellular Ca2+ concentration increases in cultured rat forebrain neurons

    Kari R. Hoyt;Stuart R. Arden;Elias Aizenman;Ian J. Reynolds

Frequent Co-Authors

Paul A. Rosenberg
Paul A. Rosenberg Boston Children's Hospital
Ian J. Reynolds
Ian J. Reynolds United States Military Academy
Stuart A. Lipton
Stuart A. Lipton Scripps Research Institute
Karl Kandler
Karl Kandler University of Pittsburgh
Edwin S. Levitan
Edwin S. Levitan University of Pittsburgh
Israel Sekler
Israel Sekler Ben-Gurion University of the Negev
Rajesh Khanna
Rajesh Khanna University of Florida
Stephen F. Traynelis
Stephen F. Traynelis Emory University
Frances E. Jensen
Frances E. Jensen University of Pennsylvania
Hongjie Yuan
Hongjie Yuan Emory University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a Neuroscience degree opens the door to various interdisciplinary career paths in healthcare, research, and mental health services. Many students interested in brain science also look to related online programs to expand their opportunities and advance their qualifications.

For those looking toward clinical social work, an accelerated masters in social work can provide practical skills for supporting individuals and families with neurological and psychological challenges. Similarly, an online psychology degree is a popular pathway for neuroscience graduates to delve deeper into human behavior, mental processes, and therapeutic techniques.

If your goal is counseling or therapy, programs recognized for quality and affordability are vital. Choosing a cacrep accredited counseling program ensures a curriculum that meets rigorous national standards. Cost-conscious students may also want to explore the cheapest mental health counseling degree options available online to earn credentials without incurring excessive debt.

Combining a neuroscience background with these related degrees can create a flexible, in-demand skillset for careers in brain research, clinical practice, education, and beyond.

Best Scientists Citing Elias Aizenman

Trending Scientists

Recently Published Articles