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Neuroscience

D-Index
34
Citations
5282
World Ranking
9311
National Ranking
3933

Research.com Recognitions

  • 1999 - Fellow of Alfred P. Sloan Foundation

Overview

Karl Kandler is affiliated with the University of Pittsburgh in the United States and is an active contributor to the field of neuroscience. Their research primarily focuses on sensory systems, cognitive neuroscience, and cellular and molecular neuroscience, with additional work in biomedical engineering and endocrine and autonomic systems.

The main topics of Kandler's research include:

  • Hearing, Cochlea, Tinnitus, Genetics
  • Hearing Loss and Rehabilitation
  • Acoustic Wave Phenomena Research
  • Neural dynamics and brain function
  • Neuroscience and Neuropharmacology Research
  • Photoreceptor and optogenetics research
  • Neuroscience and Neural Engineering

Kandler has published extensively in several prominent journals. Frequent venues include:

  • Journal of Neuroscience
  • Scientific Reports
  • Hearing Research

Some of the recent papers authored or co-authored by Kandler include:

  • Outer Hair Cell Glutamate Signaling through Type II Spiral Ganglion Afferents Activates Neurons in the Cochlear Nucleus in Response to Nondamaging Sounds (2021, Journal of Neuroscience)
  • Role of GluA3 AMPA Receptor Subunits in the Presynaptic and Postsynaptic Maturation of Synaptic Transmission and Plasticity of Endbulb−Bushy Cell Synapses in the Cochlear Nucleus (2020, Journal of Neuroscience)
  • Long-term potentiation of glycinergic synapses by semi-natural stimulation patterns during tonotopic map refinement (2020, Scientific Reports)
  • Embryonic medial ganglionic eminence cells survive and integrate into the inferior colliculus of adult mice (2022, Hearing Research)
  • Author Correction: Long-term potentiation of glycinergic synapses by semi-natural stimulation patterns during tonotopic map refinement (2021, Scientific Reports)

Kandler frequently collaborates with several researchers, including:

  • María E. Rubio
  • Eva C. Bach
  • Catherine J.C. Weisz
  • Sean-Paul G. Williams
  • Chad S. Eckard

Kandler's contributions are situated mainly within neuroscientific investigations of auditory processing and neural plasticity, exploring cellular mechanisms associated with hearing and synaptic transmission.

In 1999, Kandler was recognized as a Fellow of the Alfred P. Sloan Foundation.

Best Publications

  • Sensorineural Deafness and Seizures in Mice Lacking Vesicular Glutamate Transporter 3

    Rebecca P. Seal;Omar Akil;Eunyoung Yi;Christopher M. Weber

  • Pre- and postnatal development of efferent connections of the cochlear nucleus in the rat.

    Karl Kandler;Eckhard Friauf

  • Tonotopic reorganization of developing auditory brainstem circuits.

    Karl Kandler;Amanda Clause;Amanda Clause;Jihyun Noh

  • Patterns of excitation and inhibition evoked by horizontal connections in visual cortex share a common relationship to orientation columns

    Michael Weliky;Karl Kandler;David Fitzpatrick;Lawrence C. Katz

  • Development of glycinergic and glutamatergic synaptic transmission in the auditory brainstem of perinatal rats

    Karl Kandler;Eckhard Friauf

  • Elimination and strengthening of glycinergic/GABAergic connections during tonotopic map formation.

    Gunsoo Kim;Karl Kandler

  • Inhibitory synapses in the developing auditory system are glutamatergic.

    Deda C Gillespie;Gunsoo Kim;Karl Kandler

  • Neuronal coupling and uncoupling in the developing nervous system.

    Karl Kandler;Lawrence C Katz

  • The precise temporal pattern of prehearing spontaneous activity is necessary for tonotopic map refinement.

    Amanda Clause;Gunsoo Kim;Mandy Sonntag;Catherine J.C. Weisz

  • Coordination of Neuronal Activity in Developing Visual Cortex by Gap Junction-Mediated Biochemical Communication

    Karl Kandler;Lawrence C. Katz

  • Glutamate co-release at GABA/glycinergic synapses is crucial for the refinement of an inhibitory map

    Jihyun Noh;Rebecca P Seal;Jessica A Garver;Robert H Edwards

  • KCC2 expression in immature rat cortical neurons is sufficient to switch the polarity of GABA responses

    Hanmi Lee;Carol Xiu-Qing Chen;Yong-Jian Liu;Elias Aizenman

  • Focal photolysis of caged glutamate produces long-term depression of hippocampal glutamate receptors

    Karl Kandler;Lawrence C. Katz;Lawrence C. Katz;Julie A. Kauer

  • Activity-dependent organization of inhibitory circuits: lessons from the auditory system.

    Karl Kandler

  • Developmental refinement of inhibitory sound-localization circuits

    Karl Kandler;Deda C. Gillespie

  • Auditory projections from the cochlear nucleus to pontine and mesencephalic reticular nuclei in the rat

    Karl Kandler;Horst Herbert

  • Noise Trauma-Induced Behavioral Gap Detection Deficits Correlate with Reorganization of Excitatory and Inhibitory Local Circuits in the Inferior Colliculus and Are Prevented by Acoustic Enrichment.

    Joshua J. Sturm;Ying-Xin Zhang-Hooks;Hannah Roos;Tuan Nguyen

  • Intracellular zinc inhibits KCC2 transporter activity.

    Michal Hershfinkel;Karl Kandler;Megan E Knoch;Megan E Knoch;Michal Dagan-Rabin

  • Microglia induce neurotoxicity via intraneuronal Zn2+ release and a K+ current surge

    Megan E. Knoch;Karen A. Hartnett;Hirokazu Hara;Karl Kandler

  • Glycinergic and GABAergic calcium responses in the developing lateral superior olive.

    Paul H. M. Kullmann;F. Aura Ene;Karl Kandler

  • Development of Electrical Membrane Properties and Discharge Characteristics of Superior Olivary Complex Neurons in Fetal and Postnatal Rats

    Karl Kandler;Eckhard Friauf

Frequent Co-Authors

Elias Aizenman
Elias Aizenman University of Pittsburgh
Eckhard Friauf
Eckhard Friauf Technical University of Kaiserslautern
Rebecca P. Seal
Rebecca P. Seal University of Pittsburgh
Robert H. Edwards
Robert H. Edwards University of California, San Francisco
Peter L. Strick
Peter L. Strick University of Pittsburgh
Elisabeth Glowatzki
Elisabeth Glowatzki Johns Hopkins University School of Medicine
Jeffrey L. Noebels
Jeffrey L. Noebels Baylor College of Medicine
Julie A. Kauer
Julie A. Kauer Stanford University
Lawrence C. Katz
Lawrence C. Katz Howard Hughes Medical Institute

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