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Neuroscience

D-Index
42
Citations
8630
World Ranking
7578
National Ranking
3266

Overview

Rebecca P. Seal is affiliated with the University of Pittsburgh in the United States, with a research focus spanning multiple areas within neuroscience and medicine. Their scholarly contributions cover Neuroscience, Medicine, and Biochemistry, Genetics and Molecular Biology, emphasizing cellular and molecular aspects of neurological function and pathology.

Seal's work explores several subfields including Cellular and Molecular Neuroscience, Physiology, Molecular Biology, Neurology, and Cognitive Neuroscience. Their main research topics encompass Pain Mechanisms and Treatments, Neuroscience and Neuropharmacology Research, Hearing, Cochlea, Tinnitus, Genetics, Ion Channel Regulation and Function, RNA Research and Splicing, Neurological Disorders and Treatments, and Neurobiology and Insect Physiology Research.

Frequent collaborators in their research include Cynthia M. Arokiaraj, Myung-chul Noh, Theodore J. Price, Michael J. Leone, and Kelly A. Corrigan.

Rebecca P. Seal has published notably in venues such as bioRxiv (Cold Spring Harbor Laboratory), Neuron, Journal of Neuroscience, Nature Reviews Disease Primers, and JCI Insight. The bulk of their publications appear in bioRxiv with eight contributions, followed by three articles in Neuron.

Selected recent papers by Seal demonstrate a focus on neural mechanisms related to pain and sensory processing:

  • "Mechanical Allodynia Circuitry in the Dorsal Horn Is Defined by the Nature of the Injury," 2020, Neuron
  • "Central Neuropathic Pain," 2023, Nature Reviews Disease Primers
  • "A Functional Topographic Map for Spinal Sensorimotor Reflexes," 2020, Neuron
  • "Human Cells and Networks of Pain: Transforming Pain Target Identification and Therapeutic Development," 2021, Neuron
  • "Outer Hair Cell Glutamate Signaling through Type II Spiral Ganglion Afferents Activates Neurons in the Cochlear Nucleus in Response to Nondamaging Sounds," 2021, Journal of Neuroscience

Best Publications

  • VGLUTs define subsets of excitatory neurons and suggest novel roles for glutamate

    Robert T. Fremeau;Susan M. Voglmaier;Rebecca P. Seal;Robert H. Edwards

  • Molecular pharmacology of glutamate transporters, EAATs and VGLUTs.

    Yasushi Shigeri;Rebecca P Seal;Keiko Shimamoto

  • Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors

    Rebecca P. Seal;Xingmei Wang;Yabo Guan;Srinivasa N. Raja

  • Neural circuits for pain: Recent advances and current views.

    Cedric Peirs;Rebecca P. Seal

  • Sensorineural Deafness and Seizures in Mice Lacking Vesicular Glutamate Transporter 3

    Rebecca P. Seal;Omar Akil;Eunyoung Yi;Christopher M. Weber

  • Restoration of hearing in the VGLUT3 knockout mouse using virally mediated gene therapy.

    Omar Akil;Rebecca P. Seal;Kevin Burke;Chuansong Wang

  • Excitatory amino acid transporters: a family in flux.

    R. P. Seal;S. G. Amara

  • Dorsal Horn Circuits for Persistent Mechanical Pain.

    Cedric Peirs;Sean-Paul G. Williams;Xinyi Zhao;Claire E. Walsh

  • Expression of the vesicular glutamate transporters during development indicates the widespread corelease of multiple neurotransmitters

    Jean‐Luc Boulland;Tayyaba Qureshi;Rebecca P. Seal;Amina Rafiki

  • Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system.

    Shannon D. Shields;Hye-Sook Ahn;Yang Yang;Chongyang Han

  • A glutamatergic reward input from the dorsal raphe to ventral tegmental area dopamine neurons.

    Jia Qi;Shiliang Zhang;Hui-Ling Wang;Huikun Wang

  • Glutamate co-release at GABA/glycinergic synapses is crucial for the refinement of an inhibitory map

    Jihyun Noh;Rebecca P Seal;Jessica A Garver;Robert H Edwards

  • Making sense out of spinal cord somatosensory development.

    Helen C. Lai;Rebecca P. Seal;Jane E. Johnson

  • Cholinergic Interneurons Mediate Fast VGluT3-Dependent Glutamatergic Transmission in the Striatum

    Michael J. Higley;Aryn H. Gittis;Ian Anton Oldenburg;Nina Balthasar

  • Striatal Cholinergic Interneurons Drive GABA Release from Dopamine Terminals

    Alexandra B. Nelson;Nora Hammack;Cindy F. Yang;Nirao M. Shah

  • Mechanical Allodynia Circuitry in the Dorsal Horn Is Defined by the Nature of the Injury.

    Cedric Peirs;Sean-Paul G. Williams;Xinyi Zhao;Cynthia M. Arokiaraj

  • A Model for the Topology of Excitatory Amino Acid Transporters Determined by the Extracellular Accessibility of Substituted Cysteines

    Rebecca P. Seal;Barbara H. Leighton;Susan G. Amara

  • A non-canonical pathway from cochlea to brain signals tissue-damaging noise.

    Emma N. Flores;Anne Duggan;Thomas Madathany;Ann K. Hogan

  • TAFA4, a Chemokine-like Protein, Modulates Injury-Induced Mechanical and Chemical Pain Hypersensitivity in Mice

    Marie-Claire Delfini;Annabelle Mantilleri;Stéphane Gaillard;Jizhe Hao

  • Uncovering the Cells and Circuits of Touch in Normal and Pathological Settings.

    Francie Moehring;Priyabrata Halder;Rebecca P. Seal;Cheryl L. Stucky

  • A reentrant loop domain in the glutamate carrier EAAT1 participates in substrate binding and translocation.

    Rebecca P Seal;Susan G Amara

Frequent Co-Authors

Robert H. Edwards
Robert H. Edwards University of California, San Francisco
Anatol C. Kreitzer
Anatol C. Kreitzer University of California, San Francisco
Kim B. Seroogy
Kim B. Seroogy University of Cincinnati
Karl Kandler
Karl Kandler University of Pittsburgh
David R. Copenhagen
David R. Copenhagen University of California, San Francisco
Theodore J. Price
Theodore J. Price The University of Texas at Dallas
Gerald F. Gebhart
Gerald F. Gebhart University of Pittsburgh
Sulayman D. Dib-Hajj
Sulayman D. Dib-Hajj Yale University
John F. Smiley
John F. Smiley Nathan Kline Institute for Psychiatric Research
Allan I. Basbaum
Allan I. Basbaum University of California, San Francisco

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