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D-Index & Metrics

Neuroscience

D-Index
133
Citations
80593
World Ranking
247
National Ranking
153

Medicine

D-Index
133
Citations
80638
World Ranking
2196
National Ranking
1241

Research.com Recognitions

  • 2019 - Member of the National Academy of Sciences
  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2006 - Fellow of the Royal Society, United Kingdom
  • 2005 - Member of the National Academy of Medicine (NAM)
  • 2003 - Fellow of the American Academy of Arts and Sciences
  • 1979 - Fellow of Alfred P. Sloan Foundation

Overview

Allan I. Basbaum is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology, with a notable focus on several specialized subfields including Molecular Biology, Physiology, Cellular and Molecular Neuroscience, Pharmacology, and Cognitive Neuroscience.

The main topics of Allan I. Basbaum's work include:

  • Pain Mechanisms and Treatments
  • Receptor Mechanisms and Signaling
  • Pharmacological Receptor Mechanisms and Effects
  • Neuropeptides and Animal Physiology
  • Pain Management and Placebo Effect
  • Dermatology and Skin Diseases
  • Neurotransmitter Receptor Influence on Behavior

They have authored several papers, including recent publications such as:

  • "Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain," 2020, Nature Communications
  • "Structures of the σ2 receptor enable docking for bioactive ligand discovery," 2021, Nature
  • "Structure-based discovery of nonopioid analgesics acting through the α 2A -adrenergic receptor," 2022, Science
  • "Convergent neural representations of experimentally-induced acute pain in healthy volunteers: A large-scale fMRI meta-analysis," 2020, Neuroscience & Biobehavioral Reviews
  • "Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice," 2021, eLife

Frequent co-authors collaborating with Allan I. Basbaum include:

  • João M. Bráz
  • Veronica Craik
  • Brian K. Shoichet
  • João Braz
  • Bryan L. Roth

Their work has been published in multiple venues numerous times, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Pain
  • Proceedings of the National Academy of Sciences
  • UNC Libraries
  • Nature Communications

Allan I. Basbaum's career has been recognized through various fellowships and memberships in prestigious organizations, including membership in the National Academy of Sciences since 2019, the National Academy of Medicine since 2005, and fellowships with the American Association for the Advancement of Science (2010), the Royal Society of the United Kingdom (2006), the American Academy of Arts and Sciences (2003), and the Alfred P. Sloan Foundation (1979).

Best Publications

  • Cellular and Molecular Mechanisms of Pain

    Allan I. Basbaum;Diana M. Bautista;Grégory Scherrer;David Julius

  • Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor

    M. J. Caterina;A. Leffler;A. B. Malmberg;W. J. Martin

  • Molecular mechanisms of nociception

    David Julius;Allan I. Basbaum

  • The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli

    Makoto Tominaga;Michael J Caterina;Annika B Malmberg;Tobias A Rosen

  • Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry.

    Allan I. Basbaum;Howard L. Fields

  • TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents.

    Diana M. Bautista;Sven Eric Jordt;Tetsuro Nikai;Pamela R. Tsuruda

  • Endogenous pain control mechanisms: review and hypothesis.

    Allan I. Basbaum;Howard L. Fields

  • The menthol receptor TRPM8 is the principal detector of environmental cold

    Diana M. Bautista;Jan Siemens;Joshua M. Glazer;Pamela R. Tsuruda

  • Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition.

    Huai-hu Chuang;Elizabeth D. Prescott;Haeyoung Kong;Shannon Shields

  • Brainstem Control of Spinal Pain-Transmission Neurons

    Howard L. Fields;Allan I Basbaum

  • Central nervous system mechanisms of pain modulation

    Howard L. Fields;Allan I. Basbaum;Mary M. Heinricher

  • 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

    Marcello Trevisani;Jan Siemens;Serena Materazzi;Diana M. Bautista

  • Three bulbospinal pathways from the rostral medulla of the cat: an autoradiographic study of pain modulating systems

    A. I. Basbaum;C. H. Clanton;H. L. Fields

  • Preserved Acute Pain and Reduced Neuropathic Pain in Mice Lacking PKCγ

    Annika B. Malmberg;Chong Chen;Chong Chen;Susumu Tonegawa;Susumu Tonegawa;Allan I. Basbaum;Allan I. Basbaum

  • Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

    Daniel J. Cavanaugh;Hyosang Lee;Liching Lo;Shannon D. Shields

  • The origin of descending pathways in the dorsolateral funiculus of the spinal cord of the cat and rat: further studies on the anatomy of pain modulation.

    Allan I. Basbaum;Howard L. Fields

  • A sensory neuron–expressed IL-31 receptor mediates T helper cell–dependent itch: Involvement of TRPV1 and TRPA1

    Ferda Cevikbas;Xidao Wang;Tasuku Akiyama;Cordula Kempkes

  • Primary afferent tachykinins are required to experience moderate to intense pain

    Yu Qing Cao;Patrick W. Mantyh;Elaine J. Carlson;Anne Marie Gillespie

  • Regeneration of Sensory Axons within the Injured Spinal Cord Induced by Intraganglionic cAMP Elevation

    Simona Neumann;Frank Bradke;Marc Tessier-Lavigne;Allan I. Basbaum

  • Expression of c‐fos protein in interneurons and projection neurons of the rat spinal cord in response to noxious somatic, articular, and visceral stimulation

    D. Menétrey;A. Gannon;J. D. Levine;Allan I. Basbaum

  • Nucleus raphe magnus inhibition of spinal cord dorsal horn neurons.

    Howard L. Fields;Allan I. Basbaum;Charles H. Clanton;Stuart D. Anderson

Frequent Co-Authors

Jon D. Levine
Jon D. Levine University of California, San Francisco
David Julius
David Julius University of California, San Francisco
Howard L. Fields
Howard L. Fields University of California, San Francisco
Patrick W. Mantyh
Patrick W. Mantyh University of Arizona
William J. Martin
William J. Martin National Institutes of Health
Ida J. Llewellyn-Smith
Ida J. Llewellyn-Smith Flinders University
Scott D. Rogers
Scott D. Rogers University of Minnesota
Clifford J. Woolf
Clifford J. Woolf Boston Children's Hospital
J. Cobb Scott
J. Cobb Scott University of Pennsylvania
Lily Yeh Jan
Lily Yeh Jan University of California, San Francisco

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