D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 113 Citations 42,483 471 World Ranking 2097 National Ranking 1227

Research.com Recognitions

Awards & Achievements

1995 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Enzyme
  • Pharmacology

Frank Porreca mainly focuses on Pharmacology, Neuropathic pain, Anesthesia, Opioid and Neuroscience. Frank Porreca interconnects Agonist, Receptor, Antagonist and Cannabinoid receptor in the investigation of issues within Pharmacology. His Neuropathic pain research incorporates themes from Nerve injury, Sensory system, Dorsal root ganglion and Allodynia.

His Anesthesia research includes elements of Naltrexone, Headaches, Rostral ventromedial medulla and Nociception. His Opioid research entails a greater understanding of Internal medicine. His work investigates the relationship between Neuroscience and topics such as Hyperalgesia that intersect with problems in Cholecystokinin, Inflammation and Capsaicin.

His most cited work include:

  • Chronic pain and medullary descending facilitation (799 citations)
  • Potent and nontoxic antisense oligonucleotides containing locked nucleic acids (656 citations)
  • Central modulation of pain (628 citations)

What are the main themes of his work throughout his whole career to date?

Frank Porreca mainly investigates Pharmacology, Opioid, Receptor, Internal medicine and Endocrinology. The various areas that Frank Porreca examines in his Pharmacology study include Agonist, Antagonist and Nociception. His research on Opioid often connects related areas such as Hyperalgesia.

The Receptor study combines topics in areas such as Structure–activity relationship and Stereochemistry. Frank Porreca is exploring Neuropathic pain as part of his Neuroscience and Anesthesia and Neuropathic pain studies. His Anesthesia study combines topics in areas such as Calcitonin gene-related peptide and Rostral ventromedial medulla.

He most often published in these fields:

  • Pharmacology (39.41%)
  • Opioid (31.26%)
  • Receptor (22.81%)

What were the highlights of his more recent work (between 2013-2021)?

  • Pharmacology (39.41%)
  • Opioid (31.26%)
  • Neuroscience (17.04%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Pharmacology, Opioid, Neuroscience, Chronic pain and Neuropathic pain. His research in Pharmacology intersects with topics in Agonist, Receptor, Antagonist, Dynorphin and Dynorphin A. His biological study spans a wide range of topics, including Morphine, Central nucleus of the amygdala and Hyperalgesia, Rostral ventromedial medulla.

His study in Hyperalgesia is interdisciplinary in nature, drawing from both Endocrinology, Prolactin, Prolactin receptor and Nociceptor. His studies in Neuroscience integrate themes in fields like μ-opioid receptor and Migraine. Frank Porreca works mostly in the field of Neuropathic pain, limiting it down to topics relating to Nociception and, in certain cases, GABAA receptor.

Between 2013 and 2021, his most popular works were:

  • Descending pain modulation and chronification of pain. (298 citations)
  • Reward and motivation in pain and pain relief (248 citations)
  • The ACTTION-American Pain Society Pain Taxonomy (AAPT): An Evidence-Based and Multidimensional Approach to Classifying Chronic Pain Conditions (105 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Enzyme
  • Gene

Frank Porreca mostly deals with Chronic pain, Neuroscience, Neuropathic pain, Anesthesia and Pharmacology. The Chronic pain study combines topics in areas such as Nociception, Analgesic, Brain stimulation reward, Anxiety and Intensive care medicine. His Neuroscience research includes themes of Hyperalgesia and Opioid.

His Neuropathic pain research is multidisciplinary, incorporating elements of Gabapentin, Duloxetine, Threshold of pain and Intrathecal. His Anesthesia study incorporates themes from EGR1, Transcription factor, Gene expression and Calcitonin gene-related peptide. His Pharmacology study frequently draws connections between adjacent fields such as Allodynia.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Central modulation of pain

Michael H. Ossipov;Gregory O. Dussor;Frank Porreca.
Journal of Clinical Investigation (2010)

1024 Citations

Chronic pain and medullary descending facilitation

Frank Porreca;Michael H Ossipov;G.F Gebhart.
Trends in Neurosciences (2002)

1019 Citations

Potent and nontoxic antisense oligonucleotides containing locked nucleic acids

Claes R Wahlestedt;Peter Salmi;Liam Good;Johanna Kela.
Proceedings of the National Academy of Sciences of the United States of America (2000)

773 Citations

CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids.

Mohab M. Ibrahim;Frank Porreca;Josephine Lai;Phillip J. Albrecht.
Proceedings of the National Academy of Sciences of the United States of America (2005)

580 Citations

Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS

Mohab M. Ibrahim;Hongfeng Deng;Alexander Zvonok;Debra A. Cockayne.
Proceedings of the National Academy of Sciences of the United States of America (2003)

555 Citations

Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8.

Josephine Lai;Michael S Gold;Chang Sook Kim;Di Bian.
Pain (2002)

540 Citations

Roles of mu, delta and kappa opioid receptors in spinal and supraspinal mediation of gastrointestinal transit effects and hot-plate analgesia in the mouse.

F Porreca;H I Mosberg;R Hurst;V J Hruby.
Journal of Pharmacology and Experimental Therapeutics (1984)

535 Citations

CB2 cannabinoid receptor-mediated peripheral antinociception.

T.Philip Malan;Mohab M. Ibrahim;Hongfeng Deng;Qian Liu.
Pain (2001)

488 Citations

Unmasking the tonic-aversive state in neuropathic pain.

Tamara King;Louis Vera-Portocarrero;Tannia Gutierrez;Todd W Vanderah.
Nature Neuroscience (2009)

470 Citations

Statistical analysis of drug-drug and site-site interactions with isobolograms.

Ronald J. Tallarida;Frank Porreca;Alan Cowan.
Life Sciences (1989)

456 Citations

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