2019 - Fellow, National Academy of Inventors
1984 - Fellow of John Simon Guggenheim Memorial Foundation
1971 - Fellow of the American Association for the Advancement of Science (AAAS)
Victor J. Hruby spends much of his time researching Stereochemistry, Receptor, Internal medicine, Endocrinology and Enkephalin. Victor J. Hruby has included themes like Amino acid, Ligand, μ-opioid receptor, Side chain and Peptide in his Stereochemistry study. Biochemistry covers he research in Receptor.
His Internal medicine study frequently draws connections to adjacent fields such as Potency. His Enkephalin study combines topics in areas such as -Naloxone, δ-opioid receptor, Opioid peptide and Blood–brain barrier. His biological study spans a wide range of topics, including Glycopeptide, Pharmacology and Nociception.
Stereochemistry, Receptor, Peptide, Internal medicine and Endocrinology are his primary areas of study. Within one scientific family, Victor J. Hruby focuses on topics pertaining to Amino acid under Stereochemistry, and may sometimes address concerns connected to Organic chemistry. His Receptor study contributes to a more complete understanding of Biochemistry.
His Peptide research incorporates elements of Combinatorial chemistry, Side chain, Pharmacophore and Ligand. He focuses mostly in the field of Glucagon, narrowing it down to matters related to Cyclase and, in some cases, Adenylate kinase. Victor J. Hruby combines subjects such as δ-opioid receptor and Opioid peptide with his study of Enkephalin.
His scientific interests lie mostly in Receptor, Pharmacology, Stereochemistry, Opioid and Melanocortin. His study in Receptor is interdisciplinary in nature, drawing from both Pharmacophore and Endocrinology. His Pharmacology research integrates issues from Opioid receptor, Antagonist, κ-opioid receptor, Central nervous system and Dynorphin A.
The study incorporates disciplines such as Amino acid, DAMGO, Molecule, Selectivity and Structure–activity relationship in addition to Stereochemistry. His research integrates issues of Analgesic, Neuropathic pain, Hyperalgesia and Chronic pain in his study of Opioid. In Melanocortin, Victor J. Hruby works on issues like Peptide, which are connected to Combinatorial chemistry.
His primary areas of study are Receptor, Stereochemistry, Pharmacology, Opioid and Melanocortin. His studies link Pharmacophore with Receptor. His Stereochemistry research is multidisciplinary, relying on both Agonist, Amino acid, Structure–activity relationship and Peptide.
His work deals with themes such as Endocrinology, Antagonist, Bradykinin, Dynorphin and Internal medicine, which intersect with Pharmacology. The various areas that Victor J. Hruby examines in his Opioid study include Analgesic, Neuropathic pain and Hyperalgesia. His Melanocortin research is included under the broader classification of Biochemistry.
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A new type of synthetic peptide library for identifying ligand-binding activity
Kit S. Lam;Sydney E. Salmon;Evan M. Hersh;Victor J. Hruby.
Nature (1992)
Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
W. Fan;B. A. Boston;R. A. Kesterson;V. J. Hruby.
Nature (1997)
Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors.
Henry I. Mosberg;Robin Hurst;Victor J. Hruby;Kelvin Gee.
Proceedings of the National Academy of Sciences of the United States of America (1983)
Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
Kit Sang Lam;Sydney E. Salmon;Victor J. Hruby;Evan M. Hersh.
(1991)
Emerging approaches in the molecular design of receptor-selective peptide ligands: conformational, topographical and dynamic considerations.
V J Hruby;F al-Obeidi;W Kazmierski.
Biochemical Journal (1990)
Conformational restrictions of biologically active peptides via amino acid side chain groups
Victor J. Hruby.
Life Sciences (1982)
4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity.
Tomi K. Sawyer;Pauline J. Sanfilippo;Victor J. Hruby;Michael H. Engel.
Proceedings of the National Academy of Sciences of the United States of America (1980)
The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans
Jeffrey S. Mogil;Sonya G. Wilson;Elissa J. Chesler;Andrew L. Rankin.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Roles of mu, delta and kappa opioid receptors in spinal and supraspinal mediation of gastrointestinal transit effects and hot-plate analgesia in the mouse.
F Porreca;H I Mosberg;R Hurst;V J Hruby.
Journal of Pharmacology and Experimental Therapeutics (1984)
Peptidomimetics, a synthetic tool of drug discovery
Josef Vagner;Hongchang Qu;Victor J Hruby.
Current Opinion in Chemical Biology (2008)
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