Horst Kessler focuses on Integrin, Stereochemistry, Biochemistry, Peptide and Cyclic peptide. The Integrin study combines topics in areas such as Biophysics, Cancer research, Angiogenesis and Cell adhesion. He does research in Stereochemistry, focusing on Nuclear magnetic resonance spectroscopy specifically.
His Biochemistry study combines topics from a wide range of disciplines, such as Drug and In vivo. His Peptide research incorporates themes from Combinatorial chemistry, Structure–activity relationship and Computational biology. His Cyclic peptide research includes elements of Nuclear Overhauser effect, Crystal structure, Bioavailability, Pentapeptide repeat and Peptide bond.
The scientist’s investigation covers issues in Stereochemistry, Integrin, Peptide, Nuclear magnetic resonance spectroscopy and Biochemistry. The concepts of his Stereochemistry study are interwoven with issues in Cyclic peptide, Amino acid, Peptidomimetic and Side chain. Horst Kessler combines subjects such as Adhesion, Cell adhesion, Biophysics and Cell adhesion molecule, Cell biology with his study of Integrin.
Peptide and Combinatorial chemistry are frequently intertwined in his study. His Nuclear magnetic resonance spectroscopy research incorporates elements of Crystallography, Pulse sequence and Molecular dynamics. His Biochemistry study focuses mostly on Protein structure and Receptor.
Horst Kessler spends much of his time researching Integrin, Stereochemistry, Cell biology, Cell adhesion and Peptide. His research in Integrin intersects with topics in Biophysics, Peptidomimetic, Cell adhesion molecule and Focal adhesion. His Stereochemistry study combines topics in areas such as Amino acid, Ligand and In vivo.
His Cell biology research is multidisciplinary, incorporating elements of Integrin, beta 6, Collagen receptor, In vitro and Ligand. The concepts of his Cell adhesion study are interwoven with issues in Nanotechnology and Click chemistry. His study on Peptide is covered under Biochemistry.
Integrin, Cell adhesion, Stereochemistry, Peptide and Cell adhesion molecule are his primary areas of study. His work deals with themes such as Surface coating, Biophysics, Extracellular matrix, Cell biology and Peptidomimetic, which intersect with Integrin. His Cell adhesion study combines topics from a wide range of disciplines, such as Nanotechnology and Immunology.
His Stereochemistry research is multidisciplinary, incorporating perspectives in Transcellular, In vivo, Biodistribution, Chelation and Conjugated system. His Peptide research is under the purview of Biochemistry. Horst Kessler has researched Cell adhesion molecule in several fields, including Adhesion, Collagen receptor, Plasma protein binding and Focal adhesion.
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RGD modified polymers: biomaterials for stimulated cell adhesion and beyond
Ulrich Hersel;Claudia Dahmen;Horst Kessler.
Biomaterials (2003)
Activation of Integrin Function by Nanopatterned Adhesive Interfaces
Marco Arnold;Elisabetta Ada Cavalcanti‐Adam;Roman Glass;Jacques Blümmel.
ChemPhysChem (2004)
Conformation and Biological Activity of Cyclic Peptides
Horst Kessler.
Angewandte Chemie (1982)
N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists.
Michael A. Dechantsreiter;Eckart Planker;Barbara Mathä;Elisabeth Lohof.
Journal of Medicinal Chemistry (1999)
Cell Spreading and Focal Adhesion Dynamics Are Regulated by Spacing of Integrin Ligands
Elisabetta Ada Cavalcanti-Adam;Tova Volberg;Alexandre Micoulet;Horst Kessler.
Biophysical Journal (2007)
Assignment of carbonyl carbons and sequence analysis in peptides by heteronuclear shift correlation via small coupling constants with broadband decoupling in t1 (COLOC)
H Kessler;C Griesinger;J Zarbock;H.R Loosli.
Journal of Magnetic Resonance (1984)
Noninvasive Imaging of αvβ3 Integrin Expression Using 18F-labeled RGD-containing Glycopeptide and Positron Emission Tomography
Roland Haubner;Hans-Jürgen Wester;Wolfgang A. Weber;Christian Mang.
Cancer Research (2001)
Structural and Functional Aspects of RGD-Containing Cyclic Pentapeptides as Highly Potent and Selective Integrin αVβ3 Antagonists
Roland Haubner;Rainer Gratias;Beate Diefenbach;Simon L. Goodman.
Journal of the American Chemical Society (1996)
Arg‐Gly‐Asp constrained within cyclic pentapoptides Strong and selective inhibitors of cell adhesion to vitronectin and laminin fragment P1
Monique Aumailley;Marion Gurrath;Gerhard Müller;Juan Calvete.
FEBS Letters (1991)
Detection of Hindered Rotation and Inversion by NMR Spectroscopy
Horst Kessler.
Angewandte Chemie (1970)
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