D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 105 Citations 46,216 655 World Ranking 364 National Ranking 30

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Organic chemistry

Horst Kessler focuses on Integrin, Stereochemistry, Biochemistry, Peptide and Cyclic peptide. The Integrin study combines topics in areas such as Biophysics, Cancer research, Angiogenesis and Cell adhesion. He does research in Stereochemistry, focusing on Nuclear magnetic resonance spectroscopy specifically.

His Biochemistry study combines topics from a wide range of disciplines, such as Drug and In vivo. His Peptide research incorporates themes from Combinatorial chemistry, Structure–activity relationship and Computational biology. His Cyclic peptide research includes elements of Nuclear Overhauser effect, Crystal structure, Bioavailability, Pentapeptide repeat and Peptide bond.

His most cited work include:

  • RGD modified polymers: biomaterials for stimulated cell adhesion and beyond (1999 citations)
  • Activation of Integrin Function by Nanopatterned Adhesive Interfaces (954 citations)
  • Cell Spreading and Focal Adhesion Dynamics Are Regulated by Spacing of Integrin Ligands (697 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Stereochemistry, Integrin, Peptide, Nuclear magnetic resonance spectroscopy and Biochemistry. The concepts of his Stereochemistry study are interwoven with issues in Cyclic peptide, Amino acid, Peptidomimetic and Side chain. Horst Kessler combines subjects such as Adhesion, Cell adhesion, Biophysics and Cell adhesion molecule, Cell biology with his study of Integrin.

Peptide and Combinatorial chemistry are frequently intertwined in his study. His Nuclear magnetic resonance spectroscopy research incorporates elements of Crystallography, Pulse sequence and Molecular dynamics. His Biochemistry study focuses mostly on Protein structure and Receptor.

He most often published in these fields:

  • Stereochemistry (38.32%)
  • Integrin (20.94%)
  • Peptide (16.13%)

What were the highlights of his more recent work (between 2012-2021)?

  • Integrin (20.94%)
  • Stereochemistry (38.32%)
  • Cell biology (7.85%)

In recent papers he was focusing on the following fields of study:

Horst Kessler spends much of his time researching Integrin, Stereochemistry, Cell biology, Cell adhesion and Peptide. His research in Integrin intersects with topics in Biophysics, Peptidomimetic, Cell adhesion molecule and Focal adhesion. His Stereochemistry study combines topics in areas such as Amino acid, Ligand and In vivo.

His Cell biology research is multidisciplinary, incorporating elements of Integrin, beta 6, Collagen receptor, In vitro and Ligand. The concepts of his Cell adhesion study are interwoven with issues in Nanotechnology and Click chemistry. His study on Peptide is covered under Biochemistry.

Between 2012 and 2021, his most popular works were:

  • N-methylation of peptides and proteins: an important element for modulating biological functions. (234 citations)
  • N-methylation of peptides and proteins: an important element for modulating biological functions. (234 citations)
  • A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins. (183 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Organic chemistry

Integrin, Cell adhesion, Stereochemistry, Peptide and Cell adhesion molecule are his primary areas of study. His work deals with themes such as Surface coating, Biophysics, Extracellular matrix, Cell biology and Peptidomimetic, which intersect with Integrin. His Cell adhesion study combines topics from a wide range of disciplines, such as Nanotechnology and Immunology.

His Stereochemistry research is multidisciplinary, incorporating perspectives in Transcellular, In vivo, Biodistribution, Chelation and Conjugated system. His Peptide research is under the purview of Biochemistry. Horst Kessler has researched Cell adhesion molecule in several fields, including Adhesion, Collagen receptor, Plasma protein binding and Focal adhesion.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

RGD modified polymers: biomaterials for stimulated cell adhesion and beyond

Ulrich Hersel;Claudia Dahmen;Horst Kessler.
Biomaterials (2003)

2745 Citations

Activation of Integrin Function by Nanopatterned Adhesive Interfaces

Marco Arnold;Elisabetta Ada Cavalcanti‐Adam;Roman Glass;Jacques Blümmel.
ChemPhysChem (2004)

1156 Citations

Conformation and Biological Activity of Cyclic Peptides

Horst Kessler.
Angewandte Chemie (1982)

1076 Citations

N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists.

Michael A. Dechantsreiter;Eckart Planker;Barbara Mathä;Elisabeth Lohof.
Journal of Medicinal Chemistry (1999)

1074 Citations

Cell Spreading and Focal Adhesion Dynamics Are Regulated by Spacing of Integrin Ligands

Elisabetta Ada Cavalcanti-Adam;Tova Volberg;Alexandre Micoulet;Horst Kessler.
Biophysical Journal (2007)

876 Citations

Assignment of carbonyl carbons and sequence analysis in peptides by heteronuclear shift correlation via small coupling constants with broadband decoupling in t1 (COLOC)

H Kessler;C Griesinger;J Zarbock;H.R Loosli.
Journal of Magnetic Resonance (1984)

806 Citations

Noninvasive Imaging of αvβ3 Integrin Expression Using 18F-labeled RGD-containing Glycopeptide and Positron Emission Tomography

Roland Haubner;Hans-Jürgen Wester;Wolfgang A. Weber;Christian Mang.
Cancer Research (2001)

771 Citations

Structural and Functional Aspects of RGD-Containing Cyclic Pentapeptides as Highly Potent and Selective Integrin αVβ3 Antagonists

Roland Haubner;Rainer Gratias;Beate Diefenbach;Simon L. Goodman.
Journal of the American Chemical Society (1996)

754 Citations

Arg‐Gly‐Asp constrained within cyclic pentapoptides Strong and selective inhibitors of cell adhesion to vitronectin and laminin fragment P1

Monique Aumailley;Marion Gurrath;Gerhard Müller;Juan Calvete.
FEBS Letters (1991)

710 Citations

Detection of Hindered Rotation and Inversion by NMR Spectroscopy

Horst Kessler.
Angewandte Chemie (1970)

687 Citations

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