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Biology and Biochemistry

D-Index
61
Citations
13738
World Ranking
11319
National Ranking
107

Overview

Chaim Gilon is affiliated with the Hebrew University of Jerusalem in Israel and their research primarily spans the fields of Neuroscience and Medicine. Their work includes significant contributions to several subfields, notably Cognitive Neuroscience, Molecular Biology, Cellular and Molecular Neuroscience, Immunology and Allergy, and Organic Chemistry.

The scientist's publication record features frequent appearances in a range of journals. These include:

  • International Journal of Psychiatry Research
  • Acta Scientific Neurology
  • Journal of Psychology and Neuroscience
  • Pharmaceuticals
  • Molecular Cancer Therapeutics

Research topics covered by Gilon encompass:

  • Cell Adhesion Molecules Research
  • Photoreceptor and optogenetics research
  • Neural dynamics and brain function
  • Peptidase Inhibition and Analysis
  • Chemical Synthesis and Analysis
  • Memory and Neural Mechanisms
  • Blood Coagulation and Thrombosis Mechanisms

Key recent publications reflecting the scientist's research include:

  • Novel humanin analogs confer neuroprotection and myoprotection to neuronal and myoblast cell cultures exposed to ischemia-like and doxorubicin-induced cell death insults, 2020, Peptides
  • Cyclizing Painkillers: Development of Backbone-Cyclic TAPS Analogs, 2020, Frontiers in Chemistry
  • Interpreting Neural Morphology, 2020, Acta Scientific Neurology
  • Addressing Searle's "Problem of Consciousness", 2021, International Journal of Psychiatry Research
  • History of Chemical Notations from Alchemy to Psycho-Chemistry, 2022, Israel Journal of Chemistry

Gilon collaborates frequently with several researchers, including Gerard Marx, Amnon Hoffman, Philip Lazarovici, Michal Klazas, and Cezary Marcinkiewicz.

Best Publications

  • Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors.

    Aviv Gazit;Pnina Yaish;Chaim Gilon;Alexander Levitzki

  • Blocking of EGF-Dependent Cell Proliferation by EGF Receptor Kinase Inhibitors

    Pnina Yaish;Aviv Gazit;Chaim Gilon;Alexander Levitzki

  • N-Methylation of Peptides : A New Perspective in Medicinal Chemistry

    Jayanta Chatterjee;Chaim Gilon;Amnon Hoffman;Horst Kessler

  • Attachment of drugs to polyethylene glycols

    S. Zalipsky;C. Gilon;A. Zilkha

  • Improving oral bioavailability of peptides by multiple N-methylation: somatostatin analogues.

    Eric Biron;Jayanta Chatterjee;Oded Ovadia;Daniel Langenegger

  • The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions.

    T Volberg;Y Zick;R Dror;I Sabanay

  • Highly selective agonists for substance P receptor subtypes.

    U. Wormser;R. Laufer;Y. Hart;M. Chorev

  • Tyrphostins inhibit epidermal growth factor (EGF)-receptor tyrosine kinase activity in living cells and EGF-stimulated cell proliferation.

    R M Lyall;A Zilberstein;A Gazit;C Gilon

  • Tyrphostins. 2. Heterocyclic and alpha-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases.

    Aviv Gazit;Nir Osherov;Israel Posner;Pnina Yaish

  • Backbone cyclization: A new method for conferring conformational constraint on peptides

    C Gilon;D Halle;M Chorev;Z Selinger

  • Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin.

    Ralph Laufer;Uri Wormser;Zeev Y. Friedman;Chaim Gilon

  • Styryl compounds which inhibit EGF receptor protein tyrosine kinase

    Alexander Levitzki;Chaim Gilon;Michael Chorev;Aviv Gazit

  • Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins

    N Osherov;A Gazit;C Gilon;A Levitzki

  • In situ generation of Fmoc-amino acid chlorides using bis-(trichloromethyl)carbonate and its utilization for difficult couplings in solid-phase peptide synthesis

    E Falb;T Yechezkel;Y Salitra;C Gilon

  • Intestinal permeability of cyclic peptides: common key backbone motifs identified.

    Johannes G. Beck;Jayanta Chatterjee;Burkhardt Laufer;Marelli Udaya Kiran

  • The effect of multiple N-methylation on intestinal permeability of cyclic hexapeptides.

    Oded Ovadia;Sarit Greenberg;Jayanta Chatterjee;Burkhardt Laufer

  • Tyrphostins as molecular tools and potential antiproliferative drugs

    Alexander Levitzki;Chaim Gilon

  • Characterization of a neurokinin B receptor site in rat brain using a highly selective radioligand.

    R Laufer;C Gilon;M Chorev;Z Selinger

  • Orally Active Peptides: Is There a Magic Bullet?

    Andreas F. B. Räder;Michael Weinmüller;Florian Reichart;Adi Schumacher-Klinger

  • Tyrphostins inhibit PDGF-induced DNA synthesis and associated early events in smooth muscle cells.

    G. E. Bilder;J. A. Krawiec;K. McVety;A. Gazit

Frequent Co-Authors

Michael Chorev
Michael Chorev Harvard University
Zvi Selinger
Zvi Selinger Hebrew University of Jerusalem
Alexander Levitzki
Alexander Levitzki Hebrew University of Jerusalem
Horst Kessler
Horst Kessler Technical University of Munich
Abraham Loyter
Abraham Loyter Hebrew University of Jerusalem
Menachem Hanani
Menachem Hanani Hebrew University of Jerusalem
Gal Bitan
Gal Bitan University of California, Los Angeles
Daniel Hoyer
Daniel Hoyer University of Melbourne
Marshall Devor
Marshall Devor Hebrew University of Jerusalem
Raz Jelinek
Raz Jelinek Ben-Gurion University of the Negev

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