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William D. Lubell

William D. Lubell

D-Index & Metrics

Chemistry

D-Index
59
Citations
11282
World Ranking
10248
National Ranking
275

Overview

William D. Lubell is affiliated with the University of Montreal in Canada. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a strong focus on molecular biology and organic chemistry. Additional subfields in their work include materials chemistry, oncology, and epidemiology.

The scientist's research topics cover diverse areas, reflecting a multidisciplinary approach. Key themes in their work include:

  • Chemical Synthesis and Analysis
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Peptidase Inhibition and Analysis
  • Click Chemistry and Applications
  • Preterm Birth and Chorioamnionitis
  • Computational Drug Discovery Methods

The publication record of William D. Lubell features research articles in various well-known scientific venues. Frequent publication outlets include:

  • The Cambridge Structural Database
  • Journal of Medicinal Chemistry
  • Chemical Biology & Drug Design
  • Biomedicines
  • Journal of Peptide Science

Among recent papers authored or coauthored by the scientist are:

  • "Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aβ oligomers," 2022, Proceedings of the National Academy of Sciences
  • "An allosteric interleukin-1 receptor modulator mitigates inflammation and photoreceptor toxicity in a model of retinal degeneration," 2020, Journal of Neuroinflammation
  • "Synthesis and Biomedical Potential of Azapeptide Modulators of the Cluster of Differentiation 36 Receptor (CD36)," 2020, Biomedicines
  • "Diversity-Oriented A3-Macrocyclization for Studying Influences of Ring-Size and Shape of Cyclic Peptides: CD36 Receptor Modulators," 2021, Journal of Medicinal Chemistry
  • "Peptide-Based Drug Development," 2022, Biomedicines

The scientist collaborates frequently with several coauthors, including:

  • Sylvain Chemtob
  • Huy Ong
  • N. D. Prasad Atmuri
  • Sylvie Marleau
  • Ramakotaiah Mulamreddy

Best Publications

  • Design and synthesis of conformationally constrained amino acids as versatile scaffolds and peptide mimetics

    Stephen Hanessian;Grant McNaughton-Smith;Henry-Georges Lombart;William D. Lubell

  • Rho Signaling Pathway Targeted to Promote Spinal Cord Repair

    Pauline Dergham;Benjamin Ellezam;Charles Essagian;Hovsep Avedissian

  • Enantioselective synthesis of β-amino acids based on BINAP—ruthenium(II) catalyzed hydrogenation

    William D. Lubell;Masato Kitamura;Ryoji Noyori

  • Configurational stability of N-protected .alpha.-amino aldehydes

    William D. Lubell;Henry Rapoport

  • Azapeptides and their therapeutic potential.

    Caroline Proulx;David Sabatino;David Sabatino;Robert Hopewell;Jochen Spiegel;Jochen Spiegel

  • Steric Effects on the Amide Isomer Equilibrium of Prolyl Peptides. Synthesis and Conformational Analysis of N-Acetyl-5-tert-butylproline N‘-Methylamides

    Eric Beausoleil;William D. Lubell

  • Synthesis and reactivity of cyclic sulfamidites and sulfamidates

    Rosa E. Meléndez;William D. Lubell

  • Microglia and Interleukin-1β in Ischemic Retinopathy Elicit Microvascular Degeneration Through Neuronal Semaphorin-3A

    José Carlos Rivera;Nicholas Sitaras;Baraa Noueihed;David Hamel

  • Design, synthesis, and conformational analysis of azacycloalkane amino acids as conformationally constrained probes for mimicry of peptide secondary structures

    Liliane Halab;Francis Gosselin;William D. Lubell

  • Use of Steric Interactions To Control Peptide Turn Geometry. Synthesis of Type VI β-Turn Mimics with 5-tert-Butylproline

    Liliane Halab;William D. Lubell

  • Novel Noncompetitive IL-1 Receptor–Biased Ligand Prevents Infection- and Inflammation-Induced Preterm Birth

    Mathieu Nadeau-Vallée;Christiane Quiniou;Julia Palacios;Xin Hou

  • Cinnamoyl inhibitors of tissue transglutaminase.

    Christophe Pardin;Joelle N Pelletier;William D Lubell;Jeffrey W Keillor

  • A critical role of interleukin-1 in preterm labor.

    Mathieu Nadeau-Vallée;Dima Obari;Christiane Quiniou;William D. Lubell

  • Effect of Sequence on Peptide Geometry in 5-tert-Butylprolyl Type VI β-Turn Mimics

    Liliane Halab;William D. Lubell

  • A Novel Biased Allosteric Compound Inhibitor of Parturition Selectively Impedes the Prostaglandin F2α-mediated Rho/ROCK Signaling Pathway *

    Eugénie Goupil;Danaë Tassy;Carine Bourguet;Christiane Quiniou

  • Tetrahedron report number 776Pyrrole protection

    Benoit Jolicoeur;Erin E. Chapman;Alison Thompson;William D. Lubell

  • Antenatal Suppression of IL-1 Protects against Inflammation-Induced Fetal Injury and Improves Neonatal and Developmental Outcomes in Mice

    Mathieu Nadeau-Vallée;Peck-Yin Chin;Lydia Belarbi;Marie-Ève Brien

  • Aza-amino acid scanning of secondary structure suited for solid-phase peptide synthesis with fmoc chemistry and aza-amino acids with heteroatomic side chains.

    Damien Boeglin;William D Lubell

  • Design, synthesis, and application of azabicyclo[X.Y.0]alkanone amino acids as constrained dipeptide surrogates and peptide mimics.

    Jérôme Cluzeau;William D. Lubell

  • Systematic Study of the Synthesis of Macrocyclic Dipeptide β-Turn Mimics Possessing 8-, 9-, and 10-Membered Rings by Ring-Closing Metathesis.

    Ramesh Kaul;Simon Surprenant;William D Lubell

  • Aza-Amino Acid Scan for Rapid Identification of Secondary Structure Based on the Application of N-Boc-Aza1-Dipeptides in Peptide Synthesis

    Rosa E. Melendez;William D. Lubell

  • Analysis of N‐amino‐imidazolin‐2‐one peptide turn mimic 4‐position substituent effects on conformation by X‐ray crystallography

    Caroline Proulx;William D. Lubell

Frequent Co-Authors

Sylvain Chemtob
Sylvain Chemtob University of Montreal
Florian Sennlaub
Florian Sennlaub Institut de la Vision
X. X. Zhu
X. X. Zhu University of Montreal
Lisa McKerracher
Lisa McKerracher BioAxone BioSciences Inc.
Terence E. Hébert
Terence E. Hébert McGill University
Sarah A. Robertson
Sarah A. Robertson University of Adelaide
Henry Rapoport
Henry Rapoport University of California, Berkeley
Michel Bouvier
Michel Bouvier University of Montreal
Masato Kitamura
Masato Kitamura Nagoya University
Dirk Tourwé
Dirk Tourwé Vrije Universiteit Brussel

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